Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP. (Q37406742)

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scientific article published on 09 September 2009

Language	Label	Description	Also known as
English	Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP.	scientific article published on 09 September 2009

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Cdc42 regulates Fc gamma receptor-mediated phagocytosis through the activation and phosphorylation of Wiskott-Aldrich syndrome protein (WASP) and neural-WASP. (English)

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

phosphorylation

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1 reference

based on heuristic

inferred from title

Wiskott-Aldrich syndrome

1 reference

based on heuristic

inferred from title

0 references

author name string

Haein Park

1

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

Dianne Cox

2

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

publication date

9 September 2009

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Europe PubMed Central

PMC publication ID

20 August 2017

number of pages

9

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based on heuristic

inferred from page(s)

Molecular Biology of the Cell

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Europe PubMed Central

PMC publication ID

20 August 2017

20

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

4500-4508

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Europe PubMed Central

PMC publication ID

20 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2770938/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The mechanism of CSF-1-induced Wiskott-Aldrich syndrome protein activation in vivo: a role for phosphatidylinositol 3-kinase and Cdc42.

1 reference

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The WASP-WAVE protein network: connecting the membrane to the cytoskeleton

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Retroviral WASP gene transfer into human hematopoietic stem cells reconstitutes the actin cytoskeleton in myeloid progeny cells differentiated in vitro.

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Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP

1 reference

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The coordination of signaling during Fc receptor-mediated phagocytosis

1 reference

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Cdc42, Rac1, and Rac2 display distinct patterns of activation during phagocytosis.

1 reference

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Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein

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WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

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Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia

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A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis

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Wiskott-Aldrich syndrome protein, WASP

1 reference

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1 reference

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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome

1 reference

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Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

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Fc receptor-mediated phagocytosis requires CDC42 and Rac1.

1 reference

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Rho, Rac and Cdc42 regulate actin organization and cell adhesion in macrophages

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Cell type-specific functions of Rho GTPases revealed by gene targeting in mice.

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Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation

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A role for N-WASP in invasin-promoted internalisation.

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Murine bone marrow-derived macrophages

1 reference

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WASP-related proteins, Abi1 and Ena/VASP are required for Listeria invasion induced by the Met receptor

1 reference

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Cellular localization of activated N-WASP using a conformation-sensitive antibody

1 reference

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Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19741094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wiskott-Aldrich syndrome protein induces actin clustering without direct binding to Cdc42

1 reference

https://pubmed.ncbi.nlm.nih.gov/19741094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/19741094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19741094

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1091/MBC.E09-03-0230

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

20 August 2017

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