Novel antigens in type 1 diabetes: the importance of ZnT8. (Q37424279)

20 August 2017

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title

Novel antigens in type 1 diabetes: the importance of ZnT8. (English)

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20 August 2017

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Janet M Wenzlau

1

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20 August 2017

Lisa M Frisch

2

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20 August 2017

Thomas J Gardner

3

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20 August 2017

Suparna Sarkar

4

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20 August 2017

John C Hutton

5

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20 August 2017

Howard W Davidson

6

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20 August 2017

1 April 2009

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20 August 2017

Current diabetes report

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20 August 2017

9

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20 August 2017

2

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20 August 2017

105-112

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https://scigraph.springernature.com/pub.10.1007/s11892-009-0019-4

20 August 2017

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cites work

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

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Slc39a1 to 3 (subfamily II) Zip genes in mice have unique cell-specific functions during adaptation to zinc deficiency.

21 January 2018

1 reference

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Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes

21 January 2018

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Seizures and neuronal damage in mice lacking vesicular zinc.

21 January 2018

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12 December 2020

The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetes

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12 December 2020

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

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12 December 2020

ZnT-8, a pancreatic beta-cell-specific zinc transporter

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12 December 2020

Molecular cloning of a pancreatic islet-specific glucose-6-phosphatase catalytic subunit-related protein

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12 December 2020

Zinc is a novel intracellular second messenger

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12 December 2020

Association between anti-ZnT8 autoantibody specificities and SLC30A8 Arg325Trp variant in Japanese patients with type 1 diabetes

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12 December 2020

Beta-cell secretory products activate alpha-cell ATP-dependent potassium channels to inhibit glucagon release

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12 December 2020

Diabetes Antibody Standardization Program: First Assay Proficiency Evaluation

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12 December 2020

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

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12 December 2020

The cation efflux transporter ZnT8 (Slc30A8) is a major autoantigen in human type 1 diabetes

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12 December 2020

Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus

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12 December 2020

Observations on glucose tolerance and plasma levels of free fatty acids and insulin in the zinc-deficient rat

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12 December 2020

A common nonsynonymous single nucleotide polymorphism in the SLC30A8 gene determines ZnT8 autoantibody specificity in type 1 diabetes

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12 December 2020

Integrative aspects of zinc transporters

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12 December 2020

Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

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12 December 2020

Effects on the endocrine pancreas in Chinese hamsters fed zinc deficient diets

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12 December 2020

Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules

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12 December 2020

A gene atlas of the mouse and human protein-encoding transcriptomes

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12 December 2020

Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells.

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12 December 2020

Autoantibodies to islet antigen-2 are associated with HLA-DRB1*07 and DRB1*09 haplotypes as well as DRB1*04 at onset of type 1 diabetes: the possible role of HLA-DQA in autoimmunity to IA-2.

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12 December 2020

HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families

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12 December 2020

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

1 reference

12 December 2020

Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic alpha-cells.

1 reference

12 December 2020

A novel gene involved in zinc transport is deficient in the lethal milk mouse

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12 December 2020

Identification of pathogenic T cells in patients with beryllium-induced lung disease

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12 December 2020

Identification of protein tyrosine phosphatase-like IA2 (islet cell antigen 512) as the insulin-dependent diabetes-related 37/40K autoantigen and a target of islet-cell antibodies.

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12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

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12 December 2020

Mouse zinc transporter 1 gene provides an essential function during early embryonic development

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T cell recognition in chronic beryllium disease

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12 December 2020

Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1.

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GAD autoantibody affinity and epitope specificity identify distinct immunization profiles in children at risk for type 1 diabetes

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Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy

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Mouse pancreatic endocrine cell transcriptome defined in the embryonic Ngn3-null mouse

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Cloning and Expression of IDDM-Specific Human Autoantigens

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12 December 2020

Zinc, not insulin, regulates the rat alpha-cell response to hypoglycemia in vivo

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Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin Treatment

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Prediction of autoantibody positivity and progression to type 1 diabetes: Diabetes Autoimmunity Study in the Young (DAISY).

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12 December 2020

Regulation and function of Zip4, the acrodermatitis enteropathica gene

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12 December 2020

SLC30A8 (ZnT8) Polymorphism is Associated with Young Age at Type 1 Diabetes Onset

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12 December 2020

Identification of the beta cell antigen targeted by a prevalent population of pathogenic CD8+ T cells in autoimmune diabetes.

1 reference

12 December 2020

The mouse acrodermatitis enteropathica gene Slc39a4 (Zip4) is essential for early development and heterozygosity causes hypersensitivity to zinc deficiency

1 reference

12 December 2020

Structure of the zinc transporter YiiP

1 reference

12 December 2020

Zinc supplementation of young men alters metallothionein, zinc transporter, and cytokine gene expression in leukocyte populations

1 reference

12 December 2020

The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study

1 reference

12 December 2020

Znt7 (Slc30a7)-deficient mice display reduced body zinc status and body fat accumulation

1 reference

12 December 2020

10.1007/S11892-009-0019-4

Identifiers

DOI

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release_ekre65mi2rd4xjrp6qyntjkmmi

20 August 2017

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Fatcat

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24 November 2022

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