PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity (Q37485965)

20 August 2017

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title

PGC-1alpha-induced improvements in skeletal muscle metabolism and insulin sensitivity (English)

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20 August 2017

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Arend Bonen

1

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20 August 2017

1 June 2009

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Applied Physiology, Nutrition, and Metabolism

20 August 2017

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20 August 2017

34

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20 August 2017

3

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20 August 2017

307-314

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Exercise stimulates Pgc-1alpha transcription in skeletal muscle through activation of the p38 MAPK pathway

20 August 2017

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Functional interaction of regulatory factors with the Pgc-1alpha promoter in response to exercise by in vivo imaging

21 January 2018

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21 January 2018

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Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1.

21 January 2018

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Inverse relationship between PGC-1alpha protein expression and triacylglycerol accumulation in rodent skeletal muscle

21 January 2018

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Differential effects of contraction and PPAR agonists on the expression of fatty acid transporters in rat skeletal muscle

21 January 2018

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Modest PGC-1alpha overexpression in muscle in vivo is sufficient to increase insulin sensitivity and palmitate oxidation in subsarcolemmal, not intermyofibrillar, mitochondria

21 January 2018

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PGC-1alpha-mediated regulation of gene expression and metabolism: implications for nutrition and exercise prescriptions

21 January 2018

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PGC-1alpha increases skeletal muscle lactate uptake by increasing the expression of MCT1 but not MCT2 or MCT4.

21 January 2018

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Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

21 January 2018

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Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression

21 January 2018

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Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

21 January 2018

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Reduced expression of PGC-1 and insulin-signaling molecules in adipose tissue is associated with insulin resistance

21 January 2018

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Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

21 January 2018

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Abnormal glucose homeostasis in skeletal muscle-specific PGC-1alpha knockout mice reveals skeletal muscle-pancreatic beta cell crosstalk

21 January 2018

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PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein

21 January 2018

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PPARγ coactivator-1α expression during thyroid hormone- and contractile activity-induced mitochondrial adaptations

21 January 2018

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AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha

21 January 2018

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Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone

21 January 2018

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A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen

21 January 2018

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AMPK activation increases fatty acid oxidation in skeletal muscle by activating PPARalpha and PGC-1.

21 January 2018

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Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

21 January 2018

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PGC-1alpha is not mandatory for exercise- and training-induced adaptive gene responses in mouse skeletal muscle.

21 January 2018

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

21 January 2018

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Peroxisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta ), a novel PGC-1-related transcription coactivator associated with host cell factor

21 January 2018

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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

21 January 2018

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Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice

21 January 2018

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Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

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Rapid exercise-induced changes in PGC-1alpha mRNA and protein in human skeletal muscle

21 January 2018

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Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1.

21 January 2018

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Overexpression of peroxisome proliferator-activated receptor gamma coactivator-1alpha down-regulates GLUT4 mRNA in skeletal muscles

21 January 2018

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Overexpression of peroxisome proliferator-activated receptor gamma co-activator-1alpha leads to muscle atrophy with depletion of ATP

21 January 2018

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Raising Ca2+ in L6 myotubes mimics effects of exercise on mitochondrial biogenesis in muscle

21 January 2018

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Cold-induced PGC-1alpha expression modulates muscle glucose uptake through an insulin receptor/Akt-independent, AMPK-dependent pathway.

21 January 2018

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Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1

21 January 2018

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Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

21 January 2018

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Substrate availability and transcriptional regulation of metabolic genes in human skeletal muscle during recovery from exercise

21 January 2018

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An autosomal genomic scan for loci linked to prediabetic phenotypes in Pima Indians

21 January 2018

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

21 January 2018

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

21 January 2018

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Activation of PPARgamma coactivator-1 through transcription factor docking

21 January 2018

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Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARgamma coactivator-1.

21 January 2018

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Endurance training in humans leads to fiber type-specific increases in levels of peroxisome proliferator-activated receptor-gamma coactivator-1 and peroxisome proliferator-activated receptor-alpha in skeletal muscle.

21 January 2018

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PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

21 January 2018

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Nuclear activators and coactivators in mammalian mitochondrial biogenesis

21 January 2018

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A high-fat diet coordinately downregulates genes required for mitochondrial oxidative phosphorylation in skeletal muscle.

21 January 2018

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LKB1-AMPK signaling in muscle from obese insulin-resistant Zucker rats and effects of training

21 January 2018

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Endurance training increases skeletal muscle LKB1 and PGC-1alpha protein abundance: effects of time and intensity

21 January 2018

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Effects of acute bouts of running and swimming exercise on PGC-1α protein expression in rat epitrochlearis and soleus muscle

21 January 2018

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Effects of low-intensity prolonged exercise on PGC-1 mRNA expression in rat epitrochlearis muscle

21 January 2018

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Effects of high-intensity intermittent swimming on PGC-1alpha protein expression in rat skeletal muscle

21 January 2018

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Suppression of plasma free fatty acids upregulates peroxisome proliferator-activated receptor (PPAR) alpha and delta and PPAR coactivator 1alpha in human skeletal muscle, but not lipid regulatory genes

21 January 2018

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A role for the transcriptional coactivator PGC-1alpha in muscle refueling

21 January 2018

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Exercise-induced mitochondrial biogenesis begins before the increase in muscle PGC-1alpha expression

21 January 2018

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

21 January 2018

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Lipid Infusion Decreases the Expression of Nuclear Encoded Mitochondrial Genes and Increases the Expression of Extracellular Matrix Genes in Human Skeletal Muscle

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/H09-008

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20 August 2017

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PubMed ID

19448691