Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma. (Q37509136)

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4 March 2020

title

Functional analysis of the involvement of apurinic/apyrimidinic endonuclease 1 in the resistance to melphalan in multiple myeloma (English)

1 reference

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4 March 2020

2

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4 March 2020

author name string

Jiayin Xie

1

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4 March 2020

Mengxia Li

3

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4 March 2020

Jia Du

4

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4 March 2020

Liwei Zhou

5

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4 March 2020

Senlin Yang

6

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4 March 2020

Linli Zeng

7

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4 March 2020

Zengpeng Li

8

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4 March 2020

Ge Wang

9

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4 March 2020

Dong Wang

10

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4 March 2020

language of work or name

English

0 references

publication date

8 January 2014

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4 March 2020

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4 March 2020

volume

14

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4 March 2020

page(s)

11

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Apurinic/apyrimidinic endonuclease 1 is the essential nuclease during immunoglobulin class switch recombination

4 March 2020

cites work

1 reference

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Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin

23 August 2017

1 reference

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Human AP endonuclease (APE1/Ref-1) and its acetylation regulate YB-1-p300 recruitment and RNA polymerase II loading in the drug-induced activation of multidrug resistance gene MDR1

23 August 2017

1 reference

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Small molecule inhibitors of DNA repair nuclease activities of APE1

23 August 2017

1 reference

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Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions

23 August 2017

1 reference

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Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites

23 August 2017

1 reference

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APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

23 August 2017

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Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.

23 August 2017

1 reference

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APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

23 August 2017

1 reference

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Melphalan and its role in the management of patients with multiple myeloma.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

Mechanism of multidrug recognition by MDR1/ABCB1.

23 August 2017

1 reference

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23 August 2017

Base excision repair.

1 reference

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23 August 2017

Going APE over ref-1.

1 reference

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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

23 August 2017

1 reference

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Drug resistance: challenges to effective therapy

23 August 2017

1 reference

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Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition

6 September 2017

1 reference

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Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

Chimeric adenoviral vector Ad5/F35-mediated APE1 siRNA enhances sensitivity of human colorectal cancer cells to radiotherapy in vitro and in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

Experimental study enhancing the chemosensitivity of multiple myeloma to melphalan by using a tissue-specific APE1-silencing RNA expression vector

14 September 2017

1 reference

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DNA repair: enzymatic mechanisms and relevance to drug response

14 September 2017

1 reference

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Mutagenic damage to mammalian cells by therapeutic alkylating agents

28 September 2017

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Multifactorial resistance to adriamycin: relationship of DNA repair, glutathione transferase activity, drug efflux, and P-glycoprotein in cloned cell lines of adriamycin-sensitive and -resistant P388 leukemia.

28 September 2017

1 reference

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Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) in human ovarian cancer and indentification of the therapeutic potential of APE1/Ref-1 inhibitor.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

Repair of DNA interstrand crosslinks as a mechanism of clinical resistance to melphalan in multiple myeloma.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3900260

Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps

2 September 2018

1 reference

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Targeting truncated APE1 in mitochondria enhances cell survival after oxidative stress

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24400589

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Elevated expression of APE1/Ref-1 and its regulation on IL-6 and IL-8 in bone marrow stromal cells of multiple myeloma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24400589

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2407-14-11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24400589%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 March 2020

0 references

1 reference

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4 March 2020

PubMed publication ID

24400589

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24400589%20AND%20SRC:MED&resulttype=core&format=json