In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene (Q37519684)

20 August 2017

In vivo multiplexed interrogation of amplified genes identifies GAB2 as an ovarian cancer oncogene (English)

1 reference

20 August 2017

1 reference

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Francisca Vazquez

14

1 reference

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13 June 2020

Ronny Drapkin

17

1 reference

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13 June 2020

18

William C Hahn

1 reference

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13 June 2020

15

David E Root

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

8

Barbara A Weir

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

16

Rameen Beroukhim

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Gavin P Dunn

1

1 reference

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13 June 2020

Hiu Wing Cheung

2

1 reference

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13 June 2020

Pankaj K Agarwalla

3

1 reference

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13 June 2020

Sapana Thomas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Yulia Zektser

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Alison M Karst

6

1 reference

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13 June 2020

Aaron M Berlin

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Lihua Zou

10

1 reference

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13 June 2020

Joyce F Liu

12

1 reference

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13 June 2020

Michelle Hirsch

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Gad Getz

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

2 January 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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13 June 2020

volume

111

1 reference

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13 June 2020

page(s)

1102-1107

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer.

13 June 2020

cites work

1 reference

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Comprehensive molecular portraits of human breast tumours

23 August 2017

1 reference

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Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4

23 August 2017

1 reference

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Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers

23 August 2017

1 reference

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Dissecting "PI3Kness": the complexity of personalized therapy for ovarian cancer

23 August 2017

1 reference

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

23 August 2017

1 reference

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Genomic complexity and AKT dependence in serous ovarian cancer

23 August 2017

1 reference

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Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer

23 August 2017

1 reference

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PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations

23 August 2017

1 reference

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PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling

23 August 2017

1 reference

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Gab2 regulates the migratory behaviors and E-cadherin expression via activation of the PI3K pathway in ovarian cancer cells

23 August 2017

1 reference

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Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

23 August 2017

1 reference

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Integrated genomic analyses of ovarian carcinoma

23 August 2017

1 reference

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A public genome-scale lentiviral expression library of human ORFs

23 August 2017

1 reference

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GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

23 August 2017

1 reference

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Modeling high-grade serous ovarian carcinogenesis from the fallopian tube

23 August 2017

1 reference

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Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening

23 August 2017

1 reference

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Cooperative epigenetic modulation by cancer amplicon genes

23 August 2017

1 reference

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The biology of ovarian cancer: new opportunities for translation

23 August 2017

1 reference

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Gab2-mediated signaling promotes melanoma metastasis

23 August 2017

1 reference

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An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancer

23 August 2017

1 reference

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Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome

23 August 2017

1 reference

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Histologic subtypes of ovarian carcinoma: an overview.

23 August 2017

1 reference

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Integrative genomic approaches identify IKBKE as a breast cancer oncogene

23 August 2017

1 reference

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Amplification of a chromatin remodeling gene, Rsf-1/HBXAP, in ovarian carcinoma

23 August 2017

1 reference

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Rules for making human tumor cells

23 August 2017

1 reference

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Critical role for Gab2 in transformation by BCR/ABL

23 August 2017

1 reference

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Enumeration of the simian virus 40 early region elements necessary for human cell transformation

23 August 2017

1 reference

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

23 August 2017

1 reference

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Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

23 August 2017

1 reference

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Functional analysis of genes in regions commonly amplified in high-grade serous and endometrioid ovarian cancer

6 September 2017

1 reference

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Focal amplification and oncogene dependency of GAB2 in breast cancer

6 September 2017

1 reference

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Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models

6 September 2017

1 reference

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A role for the scaffolding adapter GAB2 in breast cancer

14 September 2017

1 reference

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Role of Gab2 in mammary tumorigenesis and metastasis.

14 September 2017

1 reference

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Amplification of 11q13 in ovarian carcinoma

2 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24385586

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1311909111

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24385586%20AND%20SRC:MED&resulttype=core&format=json