Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-β1 activity (Q37520219)

20 August 2017

Scutellaria extract and wogonin inhibit tumor-mediated induction of T(reg) cells via inhibition of TGF-β1 activity (English)

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20 August 2017

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Sagar Dandawate

1

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20 August 2017

Linford Williams

2

1 reference

20 August 2017

Nirmal Joshee

3

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20 August 2017

Agnes M Rimando

4

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20 August 2017

Sandeep Mittal

5

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20 August 2017

Archana Thakur

6

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20 August 2017

Lawrence G Lum

7

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20 August 2017

Prahlad Parajuli

8

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20 August 2017

language of work or name

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6 November 2011

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Cancer Immunology, Immunotherapy

20 August 2017

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20 August 2017

61

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20 August 2017

5

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20 August 2017

701-711

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describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3903381/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1007/s00262-011-1130-3

0 references

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A phase 1B dose escalation trial of Scutellaria barbata (BZL101) for patients with metastatic breast cancer

23 August 2017

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Glioblastoma-derived mechanisms of systemic immunosuppression

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Selective fraction of Scutellaria baicalensis and its chemopreventive effects on MCF-7 human breast cancer cells

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23 August 2017

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23 August 2017

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Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulation

23 August 2017

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23 August 2017

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TGF-beta 1 inhibition of IFN-gamma-induced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent

23 August 2017

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23 August 2017

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Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination.

23 August 2017

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Phase I trial and antitumor effects of BZL101 for patients with advanced breast cancer

23 August 2017

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Antioxidative and anti-inflammatory activities of polyhydroxyflavonoids of Scutellaria baicalensis GEORGI.

23 August 2017

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

23 August 2017

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23 August 2017

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Anticancer activity of extracts derived from the mature roots of Scutellaria baicalensis on human malignant brain tumor cells

23 August 2017

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Mechanisms of malignant glioma immune resistance and sources of immunosuppression

23 August 2017

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Tumor necrosis factor-producing activity of wogonin in RAW 264.7 murine macrophage cell line

23 August 2017

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Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation

23 August 2017

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Flavonoids: a review of probable mechanisms of action and potential applications

23 August 2017

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IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

23 August 2017

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Modulation of the immune response by transforming growth factor beta

23 August 2017

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Glycogen synthase kinase-3beta negatively regulates TGF-beta1 and Angiotensin II-mediated cellular activity through interaction with Smad3.

23 August 2017

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Naringenin: a potential immunomodulator for inhibiting lung fibrosis and metastasis

14 September 2017

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In vitro antitumor mechanisms of various Scutellaria extracts and constituent flavonoids

14 September 2017

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Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma

14 September 2017

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Chemotherapy enhances CD8(+) T cell-mediated antitumor immunity induced by vaccination with vaccinia virus

14 September 2017

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Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta

14 September 2017

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Beneficial effect of flavonoid baicalein in cisplatin-induced cell death of human glioma cells

14 September 2017

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Akt interacts directly with Smad3 to regulate the sensitivity to TGF-beta induced apoptosis

14 September 2017

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The anti-inflammatory activity of Scutellaria rivularis extracts and its active components, baicalin, baicalein and wogonin

14 September 2017

1 reference

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Transforming growth factor-beta-induced inhibition of T cell function. Susceptibility difference in T cells of various phenotypes and functions and its relevance to immunosuppression in the tumor-bearing state

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Inhibition of tumor-specific cytotoxic T-lymphocyte responses by transforming growth factor beta 1

25 June 2018

1 reference

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Baicalin and baicalein, constituents of an important medicinal plant, inhibit intracellular Ca2+ elevation by reducing phospholipase C activity in C6 rat glioma cells.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Induction of cardiac fibroblast lysyl oxidase by TGF-β1 requires PI3K/Akt, Smad3, and MAPK signaling.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Delayed growth of glioma by Scutellaria flavonoids involve inhibition of Akt, GSK-3 and NF-κB signaling

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Inhibitory effects of citrus extracts on the experimental pulmonary fibrosis.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Immunosuppressive regulatory T cells are associated with aggressive breast cancer phenotypes: a potential therapeutic target

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

The Wilms' tumor antigen is a novel target for human CD4+ regulatory T cells: implications for immunotherapy

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

TGF-beta1 modulates Foxp3 expression and regulatory activity in distinct CD4+ T cell subsets.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Concurrent induction of antitumor immunity and autoimmune thyroiditis in CD4+ CD25+ regulatory T cell-depleted mice.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Epigallocatechin-3-gallate inhibits photocarcinogenesis through inhibition of angiogenic factors and activation of CD8+ T cells in tumors

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3903381

Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma

2 September 2018

1 reference

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Genistein modulates immune responses and increases host resistance to B16F10 tumor in adult female B6C3F1 mice

2 September 2018

1 reference

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Intratumoral Cytokines and Tumor Cell Biology Determine Spontaneous Breast Cancer-Specific Immune Responses and Their Correlation to Prognosis

2 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00262-011-1130-3

Wogonin prevents immunosuppressive action but not anti-inflammatory effect induced by glucocorticoid

21 January 2018

1 reference

12 December 2020

Stress-inducing effect of hypoxia of different origin and its correction with Inula Helenium L. tincture

1 reference

12 December 2020

In vitro generation of CD4+ CD25+ regulatory cells from murine naive T cells

1 reference

12 December 2020

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta

1 reference

12 December 2020

A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

1 reference

12 December 2020

10.1007/S00262-011-1130-3

Identifiers

DOI

1 reference

20 August 2017

1 reference

20 August 2017

PubMed publication ID

22057676

1 reference