Diversity in arrestin function (Q37550019)

21 August 2017

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title

Diversity in arrestin function (English)

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21 August 2017

Louis M Luttrell

2

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author name string

Ryan T Kendall

series ordinal

1

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21 August 2017

12 July 2009

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Cellular and Molecular Life Sciences

21 August 2017

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21 August 2017

66

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21 August 2017

18

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21 August 2017

2953-2973

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https://scigraph.springernature.com/pub.10.1007/s00018-009-0088-1

21 August 2017

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cites work

beta-Arrestin1 knockout mice appear normal but demonstrate altered cardiac responses to beta-adrenergic stimulation

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Crossref

https://api.crossref.org/works/10.1007%2FS00018-009-0088-1

Enhanced morphine analgesia in mice lacking beta-arrestin 2

21 January 2018

1 reference

12 December 2020

Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors

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12 December 2020

c-Src-mediated phosphorylation of AP-2 reveals a general mechanism for receptors internalizing through the clathrin pathway

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12 December 2020

Beta-arrestin-mediated activation of MAPK by inverse agonists reveals distinct active conformations for G protein-coupled receptors

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12 December 2020

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a beta -arrestin-dependent scaffolding complex

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12 December 2020

Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes.

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12 December 2020

beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.

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12 December 2020

Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes

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12 December 2020

Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination

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12 December 2020

The solution structure and activation of visual arrestin studied by small-angle X-ray scattering

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12 December 2020

Src-dependent tyrosine phosphorylation regulates dynamin self-assembly and ligand-induced endocytosis of the epidermal growth factor receptor

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12 December 2020

beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

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12 December 2020

AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs.

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12 December 2020

Identification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3

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12 December 2020

Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy

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12 December 2020

Subcellular localization of beta-arrestins is determined by their intact N domain and the nuclear export signal at the C terminus

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12 December 2020

beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor

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12 December 2020

Morphine activates opioid receptors without causing their rapid internalization

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12 December 2020

Activation of extracellular signal-activated kinase by angiotensin II-induced Gq-independent epidermal growth factor receptor transactivation

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12 December 2020

alpha-Thrombin induces rapid and sustained Akt phosphorylation by beta-arrestin1-dependent and -independent mechanisms, and only the sustained Akt phosphorylation is essential for G1 phase progression

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12 December 2020

Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.

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12 December 2020

Targeting G protein-coupled receptor kinases to their receptor substrates

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12 December 2020

Differential nucleocytoplasmic shuttling of beta-arrestins. Characterization of a leucine-rich nuclear export signal in beta-arrestin2.

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12 December 2020

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

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12 December 2020

'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors

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12 December 2020

The structural basis of arrestin-mediated regulation of G-protein-coupled receptors

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12 December 2020

Phosphorylation of tyrosine 319 of the angiotensin II type 1 receptor mediates angiotensin II-induced trans-activation of the epidermal growth factor receptor

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12 December 2020

Interaction of the calcium-sensing receptor and filamin, a potential scaffolding protein

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12 December 2020

ERK and RhoA differentially regulate pseudopodia growth and retraction during chemotaxis

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12 December 2020

Lithium antagonizes dopamine-dependent behaviors mediated by an AKT/glycogen synthase kinase 3 signaling cascade

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12 December 2020

Essential role of dynamin in internalization of M2 muscarinic acetylcholine and angiotensin AT1A receptors

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12 December 2020

The G protein subunit gene families

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12 December 2020

Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4.

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12 December 2020

Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization

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12 December 2020

Beta-arrestin 2 functions as a G-protein-coupled receptor-activated regulator of oncoprotein Mdm2

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12 December 2020

Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin

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12 December 2020

Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

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12 December 2020

beta-arrestin 2 oligomerization controls the Mdm2-dependent inhibition of p53.

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12 December 2020

Cone arrestin binding to JNK3 and Mdm2: conformational preference and localization of interaction sites

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12 December 2020

Beta-arrestin-dependent mu-opioid receptor-activated extracellular signal-regulated kinases (ERKs) Translocate to Nucleus in Contrast to G protein-dependent ERK activation

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12 December 2020

Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling

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12 December 2020

Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2

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12 December 2020

Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes

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12 December 2020

Differential extracellular signal-regulated kinases 1 and 2 activation by the angiotensin type 1 receptor supports distinct phenotypes of cardiac myocytes.

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12 December 2020

Role of beta-arrestin-mediated desensitization and signaling in the control of angiotensin AT1a receptor-stimulated transcription

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12 December 2020

Dopamine induces a PI3-kinase-independent activation of Akt in striatal neurons: a new route to cAMP response element-binding protein phosphorylation.

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12 December 2020

Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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12 December 2020

Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

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12 December 2020

Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins

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12 December 2020

Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis

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12 December 2020

Activation of Raf as a result of recruitment to the plasma membrane

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12 December 2020

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

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12 December 2020

Seven-transmembrane receptor signaling through beta-arrestin

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12 December 2020

Pharmacological and signaling analysis of human chemokine receptor CCR-7 stably expressed in HEK-293 cells: high-affinity binding of recombinant ligands MIP-3beta and SLC stimulates multiple signaling cascades

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12 December 2020

A critical role of neural-specific JNK3 for ischemic apoptosis

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12 December 2020

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines.

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12 December 2020

Signaling from beta1- and beta2-adrenergic receptors is defined by differential interactions with PDE4

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12 December 2020

Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo

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12 December 2020

Modulation of dopamine D(2) receptor signaling by actin-binding protein (ABP-280)

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12 December 2020

The active conformation of beta-arrestin1: direct evidence for the phosphate sensor in the N-domain and conformational differences in the active states of beta-arrestins1 and -2

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12 December 2020

Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI

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12 December 2020

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

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12 December 2020

Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogen-activated protein kinase reveals the pluridimensionality of efficacy

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12 December 2020

Beta-arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes

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12 December 2020

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling

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12 December 2020

Constitutive activity of receptors coupled to guanine nucleotide regulatory proteins

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12 December 2020

Constitutive activation of phototransduction by K296E opsin is not a cause of photoreceptor degeneration

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12 December 2020

Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7.

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12 December 2020

The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals

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12 December 2020

Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors

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12 December 2020

Morphine-activated opioid receptors elude desensitization by beta-arrestin

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12 December 2020

Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors.

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12 December 2020

Beta-arrestin-mediated signaling regulates protein synthesis.

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12 December 2020

Specific beta(2)AR blocker ICI 118,551 actively decreases contraction through a G(i)-coupled form of the beta(2)AR in myocytes from failing human heart.

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12 December 2020

Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors

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12 December 2020

Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination

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12 December 2020

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

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12 December 2020

The G-protein-coupled receptor phosphatase: a protein phosphatase type 2A with a distinct subcellular distribution and substrate specificity

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12 December 2020

Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus

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12 December 2020

Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.

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12 December 2020

The beta2-adrenergic receptor/betaarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

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12 December 2020

Beta-arrestin-biased ligands at seven-transmembrane receptors

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12 December 2020

Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain

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12 December 2020

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

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12 December 2020

Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation

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12 December 2020

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways

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12 December 2020

Requirement of Gbetagamma and c-Src in D2 dopamine receptor-mediated nuclear factor-kappaB activation

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12 December 2020

Functional specialization of beta-arrestin interactions revealed by proteomic analysis

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12 December 2020

{beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase

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12 December 2020

Cell biology. A matter of life or death

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12 December 2020

c-Src regulates clathrin adapter protein 2 interaction with beta-arrestin and the angiotensin II type 1 receptor during clathrin- mediated internalization

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12 December 2020

Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor

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12 December 2020

beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation

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12 December 2020

Blocking apoptosis prevents blindness in Drosophila retinal degeneration mutants.

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12 December 2020

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

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12 December 2020

Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1

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12 December 2020

An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy

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12 December 2020

Identification of NSF as a beta-arrestin1-binding protein. Implications for beta2-adrenergic receptor regulation

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12 December 2020

Agonist-selective signaling is determined by the receptor location within the membrane domains.

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12 December 2020

Cooperative regulation of extracellular signal-regulated kinase activation and cell shape change by filamin A and beta-arrestins.

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12 December 2020

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

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12 December 2020

Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2

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12 December 2020

beta-arrestin-biased agonism at the beta2-adrenergic receptor

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12 December 2020

Control of rhodopsin activity in vision

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12 December 2020

How does arrestin assemble MAPKs into a signaling complex?

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12 December 2020

The role of sequestration in G protein-coupled receptor resensitization. Regulation of beta2-adrenergic receptor dephosphorylation by vesicular acidification

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12 December 2020

Phosphorylation and desensitization of the human beta 1-adrenergic receptor. Involvement of G protein-coupled receptor kinases and cAMP-dependent protein kinase

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12 December 2020

The origins of diversity and specificity in g protein-coupled receptor signaling

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12 December 2020

A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.

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12 December 2020

Light-dependent association of Src with photoreceptor rod outer segment membrane proteins in vivo

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12 December 2020

The specificity of extracellular signal-regulated kinase 2 dephosphorylation by protein phosphatases

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12 December 2020

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

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12 December 2020

Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.

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12 December 2020

Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor

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12 December 2020

Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2.

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12 December 2020

Arrestin-3 is essential for the activation of Fyn by the luteinizing hormone receptor (LHR) in MA-10 cells.

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12 December 2020

Functional selectivity through protean and biased agonism: who steers the ship?

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12 December 2020

Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.

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12 December 2020

A nuclear function of beta-arrestin1 in GPCR signaling: regulation of histone acetylation and gene transcription

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12 December 2020

Arrestins block G protein-coupled receptor-mediated apoptosis

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12 December 2020

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation

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12 December 2020

Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

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12 December 2020

Visual and both non-visual arrestins in their "inactive" conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm

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12 December 2020

Desensitization of G protein-coupled receptors

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12 December 2020

Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome".

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12 December 2020

Dynamic interaction between the dual specificity phosphatase MKP7 and the JNK3 scaffold protein beta-arrestin 2.

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12 December 2020

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling

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12 December 2020

beta-Arrestin inhibits NF-kappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha.

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12 December 2020

A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

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12 December 2020

The interaction of beta-arrestin with the AP-2 adaptor is required for the clustering of beta 2-adrenergic receptor into clathrin-coated pits

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12 December 2020

Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2.

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12 December 2020

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

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12 December 2020

Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors

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12 December 2020

beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis

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12 December 2020

The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation.

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12 December 2020

Actions of PP2A on the MAP kinase pathway and apoptosis are mediated by distinct regulatory subunits

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12 December 2020

Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor

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12 December 2020

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

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12 December 2020

The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration.

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12 December 2020

Real-time monitoring of ubiquitination in living cells by BRET.

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12 December 2020

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

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12 December 2020

Constitutive activity of the light-sensitive channels TRP and TRPL in the Drosophila diacylglycerol kinase mutant, rdgA.

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12 December 2020

Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor

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12 December 2020

beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport

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12 December 2020

Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins

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12 December 2020

Beta-arrestin signaling and regulation of transcription

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12 December 2020

Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection.

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12 December 2020

Monocyte chemoattractant protein-1-induced CCR2B receptor desensitization mediated by the G protein-coupled receptor kinase 2

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12 December 2020

Feedback regulation of beta-arrestin1 function by extracellular signal-regulated kinases

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12 December 2020

Characterization of the G protein-coupled receptor kinase GRK4. Identification of four splice variants

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12 December 2020

Pleckstrin homology domain-mediated membrane association and activation of the beta-adrenergic receptor kinase requires coordinate interaction with G beta gamma subunits and lipid

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12 December 2020

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

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12 December 2020

A beta-arrestin 2 signaling complex mediates lithium action on behavior

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12 December 2020

A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis

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12 December 2020

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3

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12 December 2020

Cell motility: complex dynamics at the leading edge

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12 December 2020

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

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12 December 2020

Filamin-A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase

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12 December 2020

Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A

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12 December 2020

Src-dependent phosphorylation of beta2-adaptin dissociates the beta-arrestin-AP-2 complex.

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12 December 2020

10.1007/S00018-009-0088-1

Identifiers

DOI

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21 August 2017

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PubMed ID

19597700