Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling (Q37564301)

21 August 2017

Simvastatin promotes adult hippocampal neurogenesis by enhancing Wnt/β-catenin signaling (English)

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21 August 2017

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6

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4 June 2020

author name string

Nicholas C Robin

1

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4 June 2020

Zsuzsa Agoston

2

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4 June 2020

Travis L Biechele

3

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4 June 2020

Richard G James

4

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4 June 2020

Jason D Berndt

5

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4 June 2020

publication date

26 December 2013

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21 August 2017

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4 June 2020

volume

2

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issue

1

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page(s)

9-17

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describes a project that uses

4 June 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3916759/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Secreted frizzled-related protein 3 regulates activity-dependent adult hippocampal neurogenesis

1 reference

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Targeting Wnt pathways in disease

23 August 2017

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Simvastatin promotes osteogenic differentiation of mouse embryonic stem cells via canonical Wnt/β-catenin signaling

23 August 2017

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In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics

23 August 2017

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Chemical-genetic screen identifies riluzole as an enhancer of Wnt/β-catenin signaling in melanoma

23 August 2017

1 reference

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O2 regulates stem cells through Wnt/β-catenin signalling.

23 August 2017

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Fragile x mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells

23 August 2017

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Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis.

23 August 2017

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Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage

23 August 2017

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Long-term benefits after treatment of traumatic brain injury with simvastatin in rats

23 August 2017

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Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.

23 August 2017

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Endogenous Wnt signaling maintains neural progenitor cell potency

23 August 2017

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

23 August 2017

1 reference

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Wnt signaling pathways meet Rho GTPases.

23 August 2017

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Mecp2 deficiency leads to delayed maturation and altered gene expression in hippocampal neurons

23 August 2017

1 reference

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Lovastatin protects human neurons against Abeta-induced toxicity and causes activation of beta-catenin-TCF/LEF signaling

23 August 2017

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Therapeutic intervention based on protein prenylation and associated modifications

23 August 2017

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Wnt signalling regulates adult hippocampal neurogenesis

23 August 2017

1 reference

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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors

23 August 2017

1 reference

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Transporter-mediated permeation of drugs across the blood-brain barrier

23 August 2017

1 reference

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Fibroblast growth factor-2 activates a latent neurogenic program in neural stem cells from diverse regions of the adult CNS.

23 August 2017

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Protein prenylation: molecular mechanisms and functional consequences

23 August 2017

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The discovery and development of HMG-CoA reductase inhibitors

23 August 2017

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Statins in the prevention of dementia and Alzheimer's disease: a meta-analysis of observational studies and an assessment of confounding

23 August 2017

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The contribution of the cholesterol biosynthetic pathway to intermediary metabolism and cell function

6 September 2017

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The role of isoprenoids in vascular smooth muscle: potential benefits of statins unrelated to cholesterol lowering

14 September 2017

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Brain isoprenoids farnesyl pyrophosphate and geranylgeranyl pyrophosphate are increased in aged mice

28 September 2017

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Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury

25 June 2018

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Loss of Dickkopf-1 restores neurogenesis in old age and counteracts cognitive decline.

25 June 2018

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Age-dependent rescue by simvastatin of Alzheimer's disease cerebrovascular and memory deficits.

1 September 2018

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Investigating tonic Wnt signaling throughout the adult CNS and in the hippocampal neurogenic niche of BatGal and ins-TopGal mice

1 September 2018

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Simvastatin improves cerebrovascular function and counters soluble amyloid-beta, inflammation and oxidative stress in aged APP mice.

1 September 2018

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Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

1 September 2018

1 reference

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Simvastatin reverses high glucose-induced apoptosis of mesangial cells via modulation of Wnt signaling pathway

1 September 2018

1 reference

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Simvastatin enhances learning and memory independent of amyloid load in mice.

1 September 2018

1 reference

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Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

1 September 2018

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10.1016/J.STEMCR.2013.11.002

1 September 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24511465%20AND%20SRC:MED&resulttype=core&format=json

release_6qbwidypcffbzbjblvy7oo6hqa

4 June 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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4 June 2020

PubMed publication ID

24511465

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24511465%20AND%20SRC:MED&resulttype=core&format=json