Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L. (Q37566215)

21 August 2017

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title

Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L. (English)

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21 August 2017

G W Dorn

1

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21 August 2017

L A Kirshenbaum

series ordinal

2

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21 August 2017

language of work or name

English

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publication date

1 December 2008

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21 August 2017

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21 August 2017

27 Suppl 1

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21 August 2017

S158-67

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https://scigraph.springernature.com/pub.10.1038/onc.2009.53

21 August 2017

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cites work

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Apoptosis control by death and decoy receptors

21 January 2018

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Nuclear factor-kappaB-mediated cell survival involves transcriptional silencing of the mitochondrial death gene BNIP3 in ventricular myocytes

21 January 2018

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Differential profile of Nix upregulation and translocation during hypoxia/ischaemia in vivo versus in vitro

21 January 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

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Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The pro-cell death Bcl-2 family member, BNIP3, is localized to the nucleus of human glial cells: Implications for glioblastoma multiforme tumor cell survival under hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The E1B 19K/Bcl-2-binding protein Nip3 is a dimeric mitochondrial protein that activates apoptosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The C. elegans orthologue ceBNIP3 interacts with CED-9 and CED-3 but kills through a BH3- and caspase-independent mechanism

21 January 2018

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Role of AIF in caspase-dependent and caspase-independent cell death

21 January 2018

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Cell death: critical control points

21 January 2018

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Left ventricular wall stress as a direct correlate of cardiomyocyte apoptosis in patients with severe dilated cardiomyopathy.

21 January 2018

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Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets

21 January 2018

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Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Physiologic growth and pathologic genes in cardiac development and cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Ubiquitination and degradation of the anti-apoptotic protein ARC by MDM2.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

21 January 2018

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Acidosis regulates the stability, hydrophobicity, and activity of the BH3-only protein Bnip3.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Wall stress and patterns of hypertrophy in the human left ventricle

21 January 2018

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Autophagy as a protective response to Bnip3-mediated apoptotic signaling in the heart.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Response to myocardial ischemia/reperfusion injury involves Bnip3 and autophagy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

21 January 2018

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Cell death by necrosis, a regulated way to go.

21 January 2018

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ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the [...]

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Autophagic cell death: the story of a misnomer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

TNF ligands and receptors--a matter of life and death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Apoptosis and the systolic dysfunction in congestive heart failure. Story of apoptosis interruptus and zombie myocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Bad-deficient mice develop diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Cardiac regeneration: repopulating the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Toxic proteins released from mitochondria in cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Essential role for Nix in autophagic maturation of erythroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

NIX is required for programmed mitochondrial clearance during reticulocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Response of XIAP, ARC, and FLIP apoptotic suppressors to 8 wk of treadmill running in rat heart and skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Small molecule inhibition of the Bcl-X(L)-BH3 protein-protein interaction: proof-of-concept of an in vivo chemopotentiator ABT-737.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Apoptosis in pressure overload-induced heart hypertrophy in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

Adenovirus E1B-19K/BCL-2 interacting protein BNIP3 contains a BH3 domain and a mitochondrial targeting sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2009.53

The BCL-2 protein family: opposing activities that mediate cell death

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The cell cycle factor E2F-1 activates Bnip3 and the intrinsic death pathway in ventricular myocytes

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The Ca2+-induced membrane transition in mitochondria

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Molecular and cellular mechanisms of myocardial stunning

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Death begets failure in the heart

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Regulation of Bnip3 death pathways by calcium, phosphorylation, and hypoxia-reoxygenation

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

The polymorphonuclear leukocyte and the abdominal aortic aneurysm: a neglected cell type and a neglected disease

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Upregulation of the Bcl-2 family of proteins in end stage heart failure

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Apoptosis in myocytes in end-stage heart failure

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Apoptosis in the failing human heart

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

Physiological growth synergizes with pathological genes in experimental cardiomyopathy

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2009.53

31 March 2020

Identifiers

DOI

10.1038/ONC.2009.53

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Dimensions Publication ID

21 August 2017

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