Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth (Q37568665)

21 August 2017

Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth (English)

1 reference

21 August 2017

reactive oxygen species

1 reference

0 references

12

Michael J Keating

1 reference

21 August 2017

Shira L Cramer

1

1 reference

21 August 2017

Achinto Saha

2

1 reference

21 August 2017

Jinyun Liu

3

1 reference

21 August 2017

Surendar Tadi

4

1 reference

21 August 2017

Stefano Tiziani

5

1 reference

21 August 2017

Wupeng Yan

6

1 reference

21 August 2017

Kendra Triplett

7

1 reference

21 August 2017

Candice Lamb

8

1 reference

21 August 2017

Susan E Alters

9

1 reference

21 August 2017

Scott Rowlinson

10

1 reference

21 August 2017

Yan Jessie Zhang

11

1 reference

21 August 2017

Peng Huang

13

1 reference

21 August 2017

John DiGiovanni

14

1 reference

21 August 2017

George Georgiou

15

1 reference

21 August 2017

Everett Stone

16

1 reference

21 August 2017

language of work or name

English

0 references

publication date

21 November 2016

1 reference

21 August 2017

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21 August 2017

23

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21 August 2017

1

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21 August 2017

120-127

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describes a project that uses

21 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5218918/fullTextXML

inferred from PubMed Central ID database lookup

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23 August 2017

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23 August 2017

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23 August 2017

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23 August 2017

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Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer

23 August 2017

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De novo engineering of a human cystathionine-γ-lyase for systemic (L)-Methionine depletion cancer therapy

23 August 2017

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23 August 2017

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Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia

23 August 2017

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Regulation of prostate cancer cell invasion by modulation of extra- and intracellular redox balance

23 August 2017

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Expression of cystathionine β-synthase and cystathionine γ-lyase in human pregnant myometrium and their roles in the control of uterine contractility

23 August 2017

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23 August 2017

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Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

23 August 2017

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Phasercrystallographic software

23 August 2017

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Molecular formula and METLIN Personal Metabolite Database matching applied to the identification of compounds generated by LC/TOF-MS

23 August 2017

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Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

23 August 2017

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23 August 2017

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

23 August 2017

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23 August 2017

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Thioredoxin reductase is irreversibly modified by curcumin: a novel molecular mechanism for its anticancer activity

23 August 2017

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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

23 August 2017

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23 August 2017

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Linneg Sca-1high CD49fhigh prostate cancer cells derived from the Hi-Myc mouse model are tumor-initiating cells with basal-epithelial characteristics and differentiation potential in vitro and in vivo

23 August 2017

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6 September 2017

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xCT, component of cysteine/glutamate transporter, as an independent prognostic factor in human esophageal squamous cell carcinoma

6 September 2017

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Redox implications of AMPK-mediated signal transduction beyond energetic clues

6 September 2017

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Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels

6 September 2017

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6 September 2017

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6 September 2017

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14 September 2017

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14 September 2017

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Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells

14 September 2017

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Withdrawal of essential amino acids increases autophagy by a pathway involving Ca2+/calmodulin-dependent kinase kinase-β (CaMKK-β)

14 September 2017

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Guidelines for clinical protocols for chronic lymphocytic leukemia: recommendations of the National Cancer Institute-sponsored working group

28 September 2017

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Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

28 September 2017

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System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency

25 June 2018

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A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients

25 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5218918

Increased xCT expression correlates with tumor invasion and outcome in patients with glioblastomas

1 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5218918

Reactive oxygen species signaling in cancer: comparison with aging

1 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5218918

Curcumin stimulates reactive oxygen species production and potentiates apoptosis induction by the antitumor drugs arsenic trioxide and lonidamine in human myeloid leukemia cell lines.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5218918

Site-directed mutagenesis on human cystathionine-gamma-lyase reveals insights into the modulation of H2S production

1 September 2018

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A functional transsulfuration pathway in the brain links to glutathione homeostasis

1 September 2018

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Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice

1 September 2018

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Myc-driven murine prostate cancer shares molecular features with human prostate tumors

1 September 2018

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Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism

1 September 2018

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Processing of X-ray diffraction data collected in oscillation mode

1 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4232

Optimized metabolite extraction from blood serum for 1H nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNM.4232

Cystine/glutamate antiporter expression in retinal Müller glial cells: implications for DL-alpha-aminoadipate toxicity

21 January 2018

1 reference

12 December 2020

Expression of cystathionine beta-synthase is downregulated in hepatocellular carcinoma and associated with poor prognosis

1 reference

12 December 2020

[Effect of phenethyl isothiocyanate given at different duration of gestation on the outcome of pregnancy in rats]

1 reference

12 December 2020

Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

1 reference

12 December 2020

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.4232

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

27869804

1 reference