A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism. (Q37571422)

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9 April 2020

title

A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism (English)

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9 April 2020

3

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9 April 2020

Mark A. Herman

10

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9 April 2020

author name string

Ffolliott M Fisher

1

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MiSung Kim

2

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Jeremy C Cunniff

4

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Thomas S Parker

5

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9 April 2020

Daniel M Levine

6

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Marc K Hellerstein

7

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Lisa C Hudgins

8

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Eleftheria Maratos-Flier

9

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publication date

23 November 2016

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9 April 2020

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volume

6

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page(s)

14-21

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issue

1

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ChREBP regulates fructose-induced glucose production independently of insulin signaling

9 April 2020

cites work

1 reference

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CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis

23 August 2017

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FGF21 Regulates Sweet and Alcohol Preference.

23 August 2017

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FGF21 Mediates Endocrine Control of Simple Sugar Intake and Sweet Taste Preference by the Liver

23 August 2017

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Fructose ingestion acutely stimulates circulating FGF21 levels in humans

23 August 2017

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Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

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Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding.

23 August 2017

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Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21.

23 August 2017

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Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

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Novel locus including FGF21 is associated with dietary macronutrient intake

23 August 2017

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A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

23 August 2017

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A dual sugar challenge test for lipogenic sensitivity to dietary fructose

23 August 2017

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Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease

23 August 2017

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Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes

23 August 2017

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FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

23 August 2017

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Consuming fructose-sweetened, not glucose-sweetened, beverages increases visceral adiposity and lipids and decreases insulin sensitivity in overweight/obese humans

23 August 2017

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Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

23 August 2017

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Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

23 August 2017

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23 August 2017

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Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis

23 August 2017

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1 September 2018

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1 September 2018

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1 September 2018

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1 September 2018

Identifiers

DOI

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