Cancer as a metabolic disease: implications for novel therapeutics (Q37616057)

21 August 2017

1 reference

8 February 2021

Cancer as a metabolic disease: implications for novel therapeutics (English)

1 reference

21 August 2017

1 reference

8 February 2021

1 reference

inferred from abstract

author

Thomas N. Seyfried

series ordinal

1

1 reference

21 August 2017

Roberto E Flores

2

1 reference

21 August 2017

Angela M Poff

series ordinal

3

1 reference

21 August 2017

Dominic P D'Agostino

series ordinal

4

1 reference

21 August 2017

language of work or name

English

0 references

publication date

16 December 2013

1 reference

21 August 2017

1 March 2014

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3 April 2019

8 February 2021

3 references

21 August 2017

3 April 2019

8 February 2021

35

1 reference

21 August 2017

3

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21 August 2017

515-527

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Creative Commons Attribution-NonCommercial 3.0 Unported

21 August 2017

2 references

3 April 2019

on focus list of Wikimedia project

8 February 2021

ScienceSource

0 references

cites work

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A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer

23 August 2017

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23 August 2017

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Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts

23 August 2017

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23 August 2017

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Dysfunctional oxidative phosphorylation makes malignant melanoma cells addicted to glycolysis driven by the (V600E)BRAF oncogene.

23 August 2017

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Cancer pharmacogenomics: early promise, but concerted effort needed

23 August 2017

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23 August 2017

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Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF.

23 August 2017

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Role of p90(RSK) in regulating the Crabtree effect: implications for cancer

23 August 2017

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On the origin of cancer metastasis

23 August 2017

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Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.

23 August 2017

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Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy

23 August 2017

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The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma

23 August 2017

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Kinetics, safety and tolerability of (R)-3-hydroxybutyl (R)-3-hydroxybutyrate in healthy adult subjects

23 August 2017

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Patient-derived tumour xenografts as models for oncology drug development

23 August 2017

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

23 August 2017

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Mitochondrial regulation of epigenetics and its role in human diseases

23 August 2017

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Consensus on the role of human cytomegalovirus in glioblastoma

23 August 2017

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The complexity of cardiolipin in health and disease

23 August 2017

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Aerobic glycolysis: meeting the metabolic requirements of cell proliferation

23 August 2017

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K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis

23 August 2017

1 reference

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Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy

23 August 2017

1 reference

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Mitochondrial dysfunction in cancer cells due to aberrant mitochondrial replication

23 August 2017

1 reference

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Otto Warburg's contributions to current concepts of cancer metabolism

23 August 2017

1 reference

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Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.

23 August 2017

1 reference

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Glioma-associated cytomegalovirus mediates subversion of the monocyte lineage to a tumor propagating phenotype

23 August 2017

1 reference

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Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma

23 August 2017

1 reference

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Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

23 August 2017

1 reference

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Hallmarks of Cancer: The Next Generation

23 August 2017

1 reference

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Fusion between Intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming

23 August 2017

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Cancer tumors as Metazoa 1.0: tapping genes of ancient ancestors

23 August 2017

1 reference

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Regulation of cancer cell metabolism

23 August 2017

1 reference

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Mitochondrial respiration protects against oxygen-associated DNA damage

23 August 2017

1 reference

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Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism.

23 August 2017

1 reference

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p53, Aerobic Metabolism, and Cancer

23 August 2017

1 reference

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Perspectives on the mesenchymal origin of metastatic cancer

23 August 2017

1 reference

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The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma

23 August 2017

1 reference

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Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

23 August 2017

1 reference

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The Warburg and Crabtree effects: On the origin of cancer cell energy metabolism and of yeast glucose repression

23 August 2017

1 reference

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Trafficking of UL37 proteins into mitochondrion-associated membranes during permissive human cytomegalovirus infection

23 August 2017

1 reference

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Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model

23 August 2017

1 reference

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Targeting mitochondria for cancer therapy

23 August 2017

1 reference

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Is Lamarckian evolution relevant to medicine?

23 August 2017

1 reference

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Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

23 August 2017

1 reference

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Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report

23 August 2017

1 reference

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What are the hallmarks of cancer?

23 August 2017

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Forward operation of adenine nucleotide translocase during F0F1-ATPase reversal: critical role of matrix substrate-level phosphorylation

23 August 2017

1 reference

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Cancer as a metabolic disease

23 August 2017

1 reference

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Evidence for mitochondrial respiratory deficiency in rat rhabdomyosarcoma cells

23 August 2017

1 reference

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Impairment of mitochondrial respiration in mouse fibroblasts by oncogenic H-RAS(Q61L)

23 August 2017

1 reference

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Is evolution Darwinian or/and Lamarckian?

23 August 2017

1 reference

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Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer

23 August 2017

1 reference

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Oxygen consumption can regulate the growth of tumors, a new perspective on the Warburg effect

23 August 2017

1 reference

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Mutational heterogeneity in human cancers: origin and consequences.

23 August 2017

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Electron microscopy morphology of the mitochondrial network in human cancer

23 August 2017

1 reference

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Mitochondrial gateways to cancer

23 August 2017

1 reference

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Increased OXPHOS activity precedes rise in glycolytic rate in H-RasV12/E1A transformed fibroblasts that develop a Warburg phenotype.

23 August 2017

1 reference

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In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours

23 August 2017

1 reference

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Succinyl-CoA synthetase is a phosphate target for the activation of mitochondrial metabolism

23 August 2017

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

23 August 2017

1 reference

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Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression

23 August 2017

1 reference

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Access of viral proteins to mitochondria via mitochondria-associated membranes

23 August 2017

1 reference

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23 August 2017

1 reference

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The story of human cytomegalovirus and cancer: increasing evidence and open questions

23 August 2017

1 reference

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The cancer cell--leukocyte fusion theory of metastasis

23 August 2017

1 reference

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Acidic lipids, H(+)-ATPases, and mechanism of oxidative phosphorylation. Physico-chemical ideas 30 years after P. Mitchell's Nobel Prize award

23 August 2017

1 reference

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Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets

23 August 2017

1 reference

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Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer

23 August 2017

1 reference

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A novel role for mitochondria in regulating epigenetic modification in the nucleus

23 August 2017

1 reference

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Ultrastructure of the mitochondrion and its bearing on function and bioenergetics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Functions and dysfunctions of mitochondrial dynamics

23 August 2017

1 reference

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Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen

23 August 2017

1 reference

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Paradoxes in carcinogenesis: new opportunities for research directions

23 August 2017

1 reference

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Glycolysis in cancer: a potential target for therapy.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Energy metabolism in tumor cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

A mitochondria-K+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cancer as an evolutionary and ecological process

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondria and cancer: is there a morphological connection?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

p53 regulates mitochondrial respiration

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondrial tumour suppressors: a genetic and biochemical update

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Tumour-cell fusion as a source of myeloid traits in cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Reappraisal of the Hansemann-Boveri hypothesis on the origin of tumors

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Targeting energy metabolism in brain cancer: review and hypothesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.

23 August 2017

1 reference

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Human embryonic stem cells express an immunogenic nonhuman sialic acid

23 August 2017

1 reference

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mtDNA mutations increase tumorigenicity in prostate cancer

23 August 2017

1 reference

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A new theory of the origin of cancer: quantum coherent entanglement, centrioles, mitosis, and differentiation

23 August 2017

1 reference

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Why do cancers have high aerobic glycolysis?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The somatic mutation theory of cancer: growing problems with the paradigm?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Reprogramming of a melanoma genome by nuclear transplantation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The therapeutic implications of ketone bodies: the effects of ketone bodies in pathological conditions: ketosis, ketogenic diet, redox states, insulin resistance, and mitochondrial metabolism

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The history of cancer epigenetics

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The TCA cycle and tumorigenesis: the examples of fumarate hydratase and succinate dehydrogenase.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cancer metabolism: facts, fantasy, and fiction

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Ketones: Metabolism's Ugly Duckling

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Role of glucose and ketone bodies in the metabolic control of experimental brain cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

On respiratory impairment in cancer cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

On the Origin of Cancer Cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Untangling the roots of cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Dietary restriction reduces angiogenesis and growth in an orthotopic mouse brain tumour model

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Ketone bodies, potential therapeutic uses

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Why is L-glutamine metabolism important to cells of the immune system in health, postinjury, surgery or infection?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

A mutator phenotype in cancer.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Tumour cell hybridization and metastasis revisited

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Aneuploidy, the somatic mutation that makes cancer a species of its own.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Horizontal transfer of DNA by the uptake of apoptotic bodies.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Anecdotal, historical and critical commentaries on genetics. Rudolph Virchow and the genetic basis of somatic ecology

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The quest by three giants of science for an understanding of cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Effects of a ketogenic diet on tumor metabolism and nutritional status in pediatric oncology patients: two case reports

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Resistance to Symptomatic Insulin Reactions after Fasting

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Nonoxidative glucose consumption during focal physiologic neural activity

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mutations in the p53 gene occur in diverse human tumour types

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

A genetic model for colorectal tumorigenesis

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Lactate rise detected by 1H NMR in human visual cortex during physiologic stimulation

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Normal genetically mosaic mice produced from malignant teratocarcinoma cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The clonal evolution of tumor cell populations

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Tumorigenicity and its suppression in cybrids of mouse and Chinese hamster cell lines

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The living state and cancer

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Tumor Mitochondria and the Bioenergetics of Cancer Cells

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The Warburg hypothesis fifty years later

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells.

23 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Selectively starving cancer cells through dietary manipulation: methods and clinical implications

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Caloric restriction reduces edema and prolongs survival in a mouse glioma model

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondria organelle transplantation: introduction of normal epithelial mitochondria into human cancer cells inhibits proliferation and increases drug sensitivity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Glutaminase isoenzymes as key regulators in metabolic and oxidative stress against cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Availability, not respiratory capacity governs oxygen consumption of solid tumors

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

AMPK-mediated increase of glycolysis as an adaptive response to oxidative stress in human cells: implication of the cell survival in mitochondrial diseases

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cancer: beyond speciation

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Electron microscopy morphology of the mitochondrial network in gliomas and their vascular microenvironment

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Exploring the genomes of cancer cells: progress and promise

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Biologically targeted cancer therapy and marginal benefits: are we making too much of too little or are we achieving too little by giving too much?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cell and tissue interactions in carcinogenesis and metastasis and their clinical significance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cancer metabolism: the Warburg effect today

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Metabolic management of brain cancer

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Energy metabolism in respiration-deficient and wild type chinese hamster fibroblasts in culture

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Hypoxia and anemia: factors in decreased sensitivity to radiation therapy and chemotherapy?

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondrial dysfunction contributes to oncogene-induced senescence.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Ketone bodies inhibit the viability of human neuroblastoma cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Ultrastructural mitochondrial pathology in human astrocytic tumors: potentials implications pro-therapeutics strategies

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Imatinib (STI571)-mediated changes in glucose metabolism in human leukemia BCR-ABL-positive cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Myocardial lactate and pyruvate metabolism

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The origin of human cancers

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Bioenergetics and the problem of tumor growth

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

K-Ras and mitochondria: dangerous liaisons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

STUDIES IN CANCER. VII. ENZYME DEFICIENCY IN HUMAN AND EXPERIMENTAL CANCER.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The plasmagene theory of the origin of cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Genome-wide identification and characterization of polygalacturonase genes in Cucumis sativus and Citrullus lanatus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Is systems biology a promising approach to resolve controversies in cancer research?

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Metastatic cancer cells with macrophage properties: evidence from a new murine tumor model

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Observations on the carbohydrate metabolism of tumours

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Gliomas are driven by glycolysis: putative roles of hexokinase, oxidative phosphorylation and mitochondrial ultrastructure.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Suppression of tumorigenicity in interspecific reconstituted cells and cybrids.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cardiolipins of mitochondria and microsomes of Jensen's sarcoma

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cytoplasmic suppression of malignancy

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cytoplasmic mediation of malignancy

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cytoplasmic suppression of tumorigenicity in reconstructed mouse cells

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Studies on the formation of lactate and pyruvate from glucose in cultured skin fibroblasts: implications for detection of respiratory chain defects.

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Aerobic glycolysis during lymphocyte proliferation

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Survival in patients with glioblastoma receiving valganciclovir

25 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Therapeutic ketosis with ketone ester delays central nervous system oxygen toxicity seizures in rats.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Steering cancer genomics into the fast lane.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

1 September 2018

Grappling with cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Identity and function of a large gene network underlying mutagenic repair of DNA breaks

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Targeting insulin inhibition as a metabolic therapy in advanced cancer: a pilot safety and feasibility dietary trial in 10 patients

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The bio-energetic theory of carcinogenesis

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Composition of molecular cardiolipin species correlates with proliferation of lymphocytes.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Glutaminolysis: Supplying carbon or nitrogen or both for cancer cells?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Does the existing standard of care increase glioblastoma energy metabolism?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondrial Complex I decrease is responsible for bioenergetic dysfunction in K-ras transformed cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Cancer abolishes the tissue type-specific differences in the phenotype of energetic metabolism.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondrial oxidative phosphorylation is regulated by fructose 1,6-bisphosphate. A possible role in Crabtree effect induction?

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Finding an "Achilles' heel" of cancer: the role of glucose and glutamine metabolism in the survival of transformed cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Glutamine prevents DMBA-induced squamous cell cancer

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Evolutionary biology of cancer.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Hyperoxia decreases muscle glycogenolysis, lactate production, and lactate efflux during steady-state exercise

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The retrograde response links metabolism with stress responses, chromatin-dependent gene activation, and genome stability in yeast aging.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

ANT2 expression under hypoxic conditions produces opposite cell-cycle behavior in 143B and HepG2 cancer cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mouse embryos cloned from brain tumors

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Mitochondrial impairment in p53-deficient human cancer cells

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

The bioenergetic signature of cancer: a marker of tumor progression.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Expression of mouse sialic acid on gangliosides of a human glioma grown as a xenograft in SCID mice.

1 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3941741

Seeing the Warburg effect in the developing retina

1 September 2018

1 reference

12 December 2020

Anticancer drugs that target metabolism: Is dichloroacetate the new paradigm?

1 reference

12 December 2020

On respiratory impairment in cancer cells

1 reference

12 December 2020

Physiological parameters in laboratory animals and humans

1 reference

12 December 2020

1 reference

12 December 2020

Effect of Glucose administered in vivo or in vitro on the Respiratory Quotient of Rat Liver Tissue after Partial Hepatectomy

1 reference

12 December 2020

Glutamine metabolism in AS-30D hepatoma cells. Evidence for its conversion into lipids via reductive carboxylation

1 reference

12 December 2020

Spectroscopic evidence of metabolic control

1 reference

12 December 2020

Transplantation of pluripotential nuclei from triploid frog tumors

1 reference

12 December 2020

On the significance of glucolysis for cancer growth, with special reference to Morris rat hepatomas

1 reference

12 December 2020

Positional distribution of fatty acids in the phospholipids of regenerating rat liver

1 reference

12 December 2020

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

1 reference

12 December 2020

The analysis of malignancy by cell fusion. VIII. Evidence for the intervention of an extra-chromosomal element

1 reference

12 December 2020

Do some malignant melanoma cells share antigens with the myeloid monocyte lineage?

1 reference

12 December 2020

Identifiers

DOI

10.1093/CARCIN/BGT480

1 reference

21 August 2017

1 reference

21 August 2017

PubMed publication ID

24343361

1 reference