Cancer metabolism: the Warburg effect today (Q37784056)

23 August 2017

Cancer metabolism: the Warburg effect today (English)

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23 August 2017

Leonardo M R Ferreira

series ordinal

1

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23 August 2017

8 September 2010

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Experimental and Molecular Pathology

23 August 2017

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23 August 2017

89

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23 August 2017

3

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23 August 2017

372-380

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Mitochondrial O2*- and H2O2 mediate glucose deprivation-induced stress in human cancer cells.

23 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Uncoupling protein-2 and cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The impact of O2 availability on human cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Maximum activities of key enzymes of glycolysis, glutaminolysis, pentose phosphate pathway and tricarboxylic acid cycle in normal, neoplastic and suppressed cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Cancer cachexia demonstrates the energetic impact of gluconeogenesis in human metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Studies in tissue metabolism: The effect of fumarate and succinate on tumour respiration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Hypoxia causes downregulation of protein and RNA synthesis in noncontracting Mammalian cardiomyocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Observations on the carbohydrate metabolism of tumours

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The metabolism of normal and tumour tissue: The respiratory quotient, and the relationship of respiration to glycolysis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Ammonia derived from glutaminolysis is a diffusible regulator of autophagy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Inhibitory effect of tumor cell-derived lactic acid on human T cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Fundamental Concepts of the Angiogenic Process

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondria in cancer: not just innocent bystanders

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Imaging angiogenesis and the microenvironment

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Cervix cancer oxygenation measured following external radiation therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis?

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

ATP citrate lyase inhibition can suppress tumor cell growth

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Interstitial pH and pO2 gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Cell surface oxygen consumption: a major contributor to cellular oxygen consumption in glycolytic cancer cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Linkage of aerobic glycolysis to sodium-potassium transport in rat skeletal muscle. Implications for increased muscle lactate production in sepsis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Tumor suppressors and cell metabolism: a recipe for cancer growth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Linoleic acid induces mouse embryonic stem cell proliferation via Ca2+/PKC, PI3K/Akt, and MAPKs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondrial complex III regulates hypoxic activation of HIF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondrial metabolism of glutamine and glutamate and its physiological significance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Tumor cell metabolism: cancer's Achilles' heel

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Hydrogen peroxide-induced expression of the proto-oncogenes, c-jun, c-fos and c-myc in rabbit lens epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Glucose deprivation induces mitochondrial dysfunction and oxidative stress in PC12 cell line.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1α expression through activation of AKT and P70S6K1 in human ovarian cancer cells

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The warburg effect: why and how do cancer cells activate glycolysis in the presence of oxygen?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

p53 regulates mitochondrial respiration

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondrial DNA mutations in renal cell carcinomas revealed no general impact on energy metabolism

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Facilitative glucose transporters

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Regulation of glycogen phosphorylase and PDH during exercise in human skeletal muscle during hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Positron-emission tomography with [18F]fluorodeoxyglucose. Part I. Biochemical uptake mechanism and its implication for clinical studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The metabolism of proline, a stress substrate, modulates carcinogenic pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Warburg Effect Revisited: Merger of Biochemistry and Molecular Biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Differences in expression and intracellular distribution of hexokinase isoenzymes in rat liver cells of different transformation stages.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Na+/H+ exchanger-dependent intracellular alkalinization is an early event in malignant transformation and plays an essential role in the development of subsequent transformation-associated phenotypes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Central carbon metabolism in the progression of mammary carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Bicarbonate increases tumor pH and inhibits spontaneous metastases

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Induction by glucose of genes coding for glycolytic enzymes in a pancreatic beta-cell line (INS-1).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Substrate oxidation and ATP supply in AS-30D hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Energy substrate modulates mitochondrial structure and oxidative capacity in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Mitochondrial uncoupling and the Warburg effect: molecular basis for the reprogramming of cancer cell metabolism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Regulation of proliferation-survival decisions during tumor cell hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Regulation of cancer cell metabolism by hypoxia-inducible factor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

A CD147-targeting siRNA inhibits the proliferation, invasiveness, and VEGF production of human malignant melanoma cells by down-regulating glycolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Intermittent hypoxia is a key regulator of cancer cell and endothelial cell interplay in tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Free radicals, metals and antioxidants in oxidative stress-induced cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Fructose 2,6-bisphosphate, the probably structure of the glucose- and glucagon-sensitive stimulator of phosphofructokinase.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

On the Origin of Cancer Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

THE METABOLISM OF TUMORS IN THE BODY

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

On respiratory impairment in cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Increased carnitine-dependent fatty acid uptake into mitochondria of human colon cancer cells induces apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Regulation of glucose metabolism by 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases in cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Heterogeneous vascular dependence of tumor cell populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Maximum activities and effects of fructose bisphosphate on pyruvate kinase from muscles of vertebrates and invertebrates in relation to the control of glycolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Expression of the fructose transporter GLUT5 in human breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Phosphoenolpyruvate carboxykinase is induced in growth-arrested hepatoma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

Cancer metabolism: facts, fantasy, and fiction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

The effect of pH on glycolysis and phosphofructokinase activity in cultured cells and synaptosomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

7 January 2021

inferred from DOI database lookup

Amino acids and glucose utilization by different metabolic pathways in ascites-tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

7 January 2021

inferred from DOI database lookup

Oxidative metabolism of neoplastic tissues

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXMP.2010.08.006

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1016/J.YEXMP.2010.08.006

1 reference

release_alttre4bw5htvmy5l6qm7dcffe

23 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/alttre4bw5htvmy5l6qm7dcffe

24 November 2022

mapped directly with Wikidata item

PubMed ID

20804748

1 reference

PubMed ID

20804748