Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305. (Q37632309)

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scientific article published on 05 June 2012

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English	Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305.	scientific article published on 05 June 2012

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3 February 2020

Ligand binding promotes CDK-dependent phosphorylation of ER-alpha on hinge serine 294 but inhibits ligand-independent phosphorylation of serine 305 (English)

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3 February 2020

phosphorylation

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3 February 2020

author name string

David J Britton

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3 February 2020

Gary K Scott

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3 February 2020

Elbert L Lee

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Birgit Schilling

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3 February 2020

Michael A Baldwin

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3 February 2020

Bradford W Gibson

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3 February 2020

Christopher C Benz

8

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publication date

5 June 2012

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3 February 2020

Molecular Cancer Research

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3 February 2020

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8

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3 February 2020

1120-1132

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3 February 2020

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Identification of four novel phosphorylation sites in estrogen receptor alpha: impact on receptor-dependent gene expression and phosphorylation by protein kinase CK2.

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ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands

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Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305.

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Immunohistochemical validation of multiple phospho-specific epitopes for estrogen receptor alpha (ERalpha) in tissue microarrays of ERalpha positive human breast carcinomas

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Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome

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Prediction of post-translational glycosylation and phosphorylation of proteins from the amino acid sequence

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Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity

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Proteasome-dependent degradation of the human estrogen receptor

1 reference

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Clinical significance of estrogen receptor phosphorylation

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1 reference

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12 December 2020

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Identifiers

10.1158/1541-7786.MCR-12-0099

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3 February 2020

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3 February 2020

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3 February 2020

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