Nitric oxide and oxidative stress in vascular disease (Q37715827)

22 August 2017

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title

Nitric oxide and oxidative stress in vascular disease (English)

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22 August 2017

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Ulrich Förstermann

1

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22 August 2017

21 March 2010

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22 August 2017

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22 August 2017

459

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22 August 2017

923-939

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22 August 2017

6

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https://scigraph.springernature.com/pub.10.1007/s00424-010-0808-2

22 August 2017

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Allopurinol Normalizes Endothelial Dysfunction in Type 2 Diabetics With Mild Hypertension

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Paraoxonase-2 reduces oxidative stress in vascular cells and decreases endoplasmic reticulum stress-induced caspase activation

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Polyphenols and prevention of cardiovascular diseases

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Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process

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Folic acid improves arterial endothelial function in adults with hyperhomocystinemia.

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A blend of polyphenolic compounds explains the stimulatory effect of red wine on human endothelial NO synthase

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Vascular extracellular superoxide dismutase activity in patients with coronary artery disease: relation to endothelium-dependent vasodilation

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Acute amelioration of diabetic endothelial dysfunction with a derivative of the nitric oxide synthase cofactor, tetrahydrobiopterin

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Effects of L-arginine on forearm vessels and responses to acetylcholine

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Comparative effect of ace inhibition and angiotensin II type 1 receptor antagonism on bioavailability of nitric oxide in patients with coronary artery disease: role of superoxide dismutase

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Ischemia‐reperfusion selectively impairs nitric oxide‐ mediated dilation in coronary arterioles: counteracting role of arginase

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Statin-sensitive dysregulated AT1 receptor function and density in hypercholesterolemic men

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12 December 2020

Arginase activity in endothelial cells: inhibition by NG-hydroxy-L-arginine during high-output NO production

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Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

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Long-Term Ascorbic Acid Administration Reverses Endothelial Vasomotor Dysfunction in Patients With Coronary Artery Disease

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PON2 gene variants are associated with clinical manifestations of cardiovascular disease in familial hypercholesterolemia patients

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Red wine increases the expression of human endothelial nitric oxide synthase: a mechanism that may contribute to its beneficial cardiovascular effects

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Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells

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Endothelial regulation of vasomotion in apoE-deficient mice: implications for interactions between peroxynitrite and tetrahydrobiopterin

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Role of neutral amino acid transport and protein breakdown for substrate supply of nitric oxide synthase in human endothelial cells.

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MnSOD deficiency increases endothelial dysfunction in ApoE-deficient mice

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The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine

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Oxygen reduction by nitric-oxide synthases

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Effects of angiotensin II infusion on the expression and function of NAD(P)H oxidase and components of nitric oxide/cGMP signaling

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Vascular effects of a common gene variant of extracellular superoxide dismutase in heart failure

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Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus

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Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease

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Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation

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Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion

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Thioredoxin: a key regulator of cardiovascular homeostasis

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Neuronal nitric oxide synthase, a modular enzyme formed by convergent evolution: structure studies of a cysteine thiolate-liganded heme protein that hydroxylates L-arginine to produce NO. as a cellular signal.

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Upregulation of renal and vascular nitric oxide synthase in young spontaneously hypertensive rats

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Effect of AT1 receptor blockade on endothelial function in essential hypertension

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Supplemention with tetrahydrobiopterin suppresses the development of hypertension in spontaneously hypertensive rats

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12 December 2020

Angiotensin-converting-enzyme inhibition in stable coronary artery disease

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12 December 2020

Oxidation of tetrahydrobiopterin by peroxynitrite: implications for vascular endothelial function.

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12 December 2020

c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells

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12 December 2020

Xanthine oxidase inhibition with oxypurinol improves endothelial vasodilator function in hypercholesterolemic but not in hypertensive patients

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12 December 2020

Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase.

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12 December 2020

NAD(P)H oxidase: role in cardiovascular biology and disease

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12 December 2020

Ursolic acid from the Chinese herb danshen (Salvia miltiorrhiza L.) upregulates eNOS and downregulates Nox4 expression in human endothelial cells

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12 December 2020

Oxidative stress in arterial hypertension: role of NAD(P)H oxidase.

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12 December 2020

LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases

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12 December 2020

Induction of heme oxygenase-1 inhibits NAD(P)H oxidase activity by down-regulating cytochrome b558 expression via the reduction of heme availability.

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12 December 2020

Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats.

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12 December 2020

Upregulation of vascular arginase in hypertension decreases nitric oxide-mediated dilation of coronary arterioles

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12 December 2020

Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium

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12 December 2020

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

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12 December 2020

Increased arginase II and decreased NO synthesis in endothelial cells of patients with pulmonary arterial hypertension

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12 December 2020

Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial

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12 December 2020

Reciprocal regulation of endothelial nitric-oxide synthase and NADPH oxidase by betulinic acid in human endothelial cells

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12 December 2020

Arginase Reciprocally Regulates Nitric Oxide Synthase Activity and Contributes to Endothelial Dysfunction in Aging Blood Vessels

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12 December 2020

Rapid kinetic studies of electron transfer in the three isoforms of nitric oxide synthase

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12 December 2020

Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen Species

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12 December 2020

Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice

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12 December 2020

Activation of protein kinase C alpha and/or epsilon enhances transcription of the human endothelial nitric oxide synthase gene.

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12 December 2020

Endothelial nitric oxide synthase in vascular disease: from marvel to menace

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12 December 2020

Tetrahydrobiopterin and dysfunction of endothelial nitric oxide synthase in coronary arteries

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12 December 2020

Protective role of heme oxygenase in the blood vessel wall during atherogenesis

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12 December 2020

Role of bound zinc in dimer stabilization but not enzyme activity of neuronal nitric-oxide synthase.

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12 December 2020

Inhibition of geranylgeranylation reduces angiotensin II-mediated free radical production in vascular smooth muscle cells: involvement of angiotensin AT1 receptor expression and Rac1 GTPase.

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12 December 2020

Resveratrol: a multifunctional compound improving endothelial function. Editorial to: "Resveratrol supplementation gender independently improves endothelial reactivity and suppresses superoxide production in healthy rats" by S. Soylemez et al.

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12 December 2020

p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats

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12 December 2020

Prognostic impact of coronary vasodilator dysfunction on adverse long-term outcome of coronary heart disease

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12 December 2020

Regulation of endothelial-type NO synthase expression in pathophysiology and in response to drugs.

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12 December 2020

Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase

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12 December 2020

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

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12 December 2020

Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression by hydrogen peroxide

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12 December 2020

Vitamin E supplementation and cardiovascular events in high-risk patients

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12 December 2020

Glutathione Peroxidase 1 Activity and Cardiovascular Events in Patients with Coronary Artery Disease

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12 December 2020

Tetrahydrobiopterin and nitric oxide: mechanistic and pharmacological aspects

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12 December 2020

Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase

1 reference

12 December 2020

Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine

1 reference

12 December 2020

Vascular hypertrophy in angiotensin II-induced hypertension is mediated by vascular smooth muscle cell-derived H2O2.

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12 December 2020

Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury

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12 December 2020

ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins

1 reference

12 December 2020

Nitric oxide synthases: structure, function and inhibition

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12 December 2020

Oral administration of tetrahydrobiopterin prevents endothelial dysfunction and vascular oxidative stress in the aortas of insulin-resistant rats

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12 December 2020

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

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12 December 2020

Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits

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12 December 2020

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress

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12 December 2020

Crystal structures of zinc-free and -bound heme domain of human inducible nitric-oxide synthase. Implications for dimer stability and comparison with endothelial nitric-oxide synthase

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12 December 2020

Potentiometric analysis of the flavin cofactors of neuronal nitric oxide synthase

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12 December 2020

Tetrahydrobiopterin-Free Neuronal Nitric Oxide Synthase: Evidence for Two Identical Highly Anticooperative Pteridine Binding Sites†

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12 December 2020

Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase

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12 December 2020

Vascular protection by dietary polyphenols

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12 December 2020

Folic acid reverses endothelial dysfunction induced by inhibition of tetrahydrobiopterin biosynthesis

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12 December 2020

Increased NADH-Oxidase–Mediated Superoxide Production in the Early Stages of Atherosclerosis

1 reference

12 December 2020

Thrombin stimulates human endothelial arginase enzymatic activity via RhoA/ROCK pathway: implications for atherosclerotic endothelial dysfunction

1 reference

12 December 2020

Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study).

1 reference

12 December 2020

The effect of insufficiency of tetrahydrobiopterin on endothelial function and vasoactivity

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12 December 2020

Heme oxygenase-1: a novel drug target for atherosclerotic diseases?

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12 December 2020

Increased expression of arginase II in human diabetic corpus cavernosum: in diabetic-associated erectile dysfunction

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12 December 2020

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease

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12 December 2020

A review of the epidemiological evidence for the 'antioxidant hypothesis'

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12 December 2020

Polyphenols and cardiovascular disease: effects on endothelial and platelet function

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12 December 2020

Structure of nitric oxide synthase oxygenase dimer with pterin and substrate

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12 December 2020

NO modulates NADPH oxidase function via heme oxygenase-1 in human endothelial cells

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12 December 2020

Nitric oxide synthase-immunoreactive nerve fibers in dog cerebral and peripheral arteries

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12 December 2020

Oxidation of tetrahydrobiopterin leads to uncoupling of endothelial cell nitric oxide synthase in hypertension

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12 December 2020

Intensive lipid lowering by statin therapy does not improve vasoreactivity in patients with type 2 diabetes

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12 December 2020

Isoforms of nitric oxide synthase: functions in the cardiovascular system

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12 December 2020

Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice

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12 December 2020

Pteridine biosynthesis in human endothelial cells. Impact on nitric oxide-mediated formation of cyclic GMP

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12 December 2020

5-Methyltetrahydrofolate, the Active Form of Folic Acid, Restores Endothelial Function in Familial Hypercholesterolemia

1 reference

12 December 2020

Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury

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12 December 2020

Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.

1 reference

12 December 2020

Electrochemistry of pterin cofactors and inhibitors of nitric oxide synthase

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12 December 2020

Effect of native and oxidized low-density lipoprotein on endothelial nitric oxide and superoxide production : key role of L-arginine availability

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12 December 2020

Enzymology of nitric oxide synthases.

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12 December 2020

Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

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12 December 2020

Role of L-arginine-nitric oxide pathway in hypertension.

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12 December 2020

Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters

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12 December 2020

Paraoxonase 1 (PON1) attenuates macrophage oxidative status: studies in PON1 transfected cells and in PON1 transgenic mice

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12 December 2020

Nitric oxide-dependent endothelial function is unaffected by allopurinol in hypercholesterolaemic subjects

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12 December 2020

ATVB in focus: redox mechanisms in blood vessels

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12 December 2020

The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.

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12 December 2020

The role of tetrahydrobiopterin in the activation of oxygen by nitric-oxide synthase

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12 December 2020

Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice.

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12 December 2020

Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase

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12 December 2020

Mitochondrial integrity and function in atherogenesis

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12 December 2020

Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E.

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12 December 2020

Tetrahydrobiopterin restores endothelial function of coronary arteries in patients with hypercholesterolaemia

1 reference

12 December 2020

Beyond lipid lowering: the role of statins in vascular protection

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12 December 2020

Hypercholesterolemia increases endothelial superoxide anion production

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12 December 2020

Arginase pathway in human endothelial cells in pathophysiological conditions.

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12 December 2020

Zinc content of Escherichia coli-expressed constitutive isoforms of nitric-oxide synthase. Enzymatic activity and effect of pterin

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12 December 2020

Interactions of peroxynitrite, tetrahydrobiopterin, ascorbic acid, and thiols: implications for uncoupling endothelial nitric-oxide synthase.

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12 December 2020

Abnormal biopterin metabolism is a major cause of impaired endothelium-dependent relaxation through nitric oxide/O2- imbalance in insulin-resistant rat aorta

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12 December 2020

Superoxide production and expression of nox family proteins in human atherosclerosis

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12 December 2020

Enhanced expression of angiotensin-converting enzyme is associated with progression of coronary atherosclerosis in humans

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12 December 2020

Arginase inhibition restores arteriolar endothelial function in Dahl rats with salt-induced hypertension

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12 December 2020

Tetrahydrobiopterin enhances forearm vascular response to acetylcholine in both normotensive and hypertensive individuals

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12 December 2020

Tetrahydrobiopterin improves endothelium-dependent vasodilation in chronic smokers : evidence for a dysfunctional nitric oxide synthase

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12 December 2020

Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity

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12 December 2020

L-arginine normalizes endothelial function in cerebral vessels from hypercholesterolemic rabbits

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12 December 2020

p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice

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12 December 2020

Simvastatin versus ezetimibe: pleiotropic and lipid-lowering effects on endothelial function in humans

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12 December 2020

The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis

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12 December 2020

Mechanisms underlying endothelial dysfunction in diabetes mellitus

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12 December 2020

Mitochondria, nitric oxide, and cardiovascular dysfunction.

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12 December 2020

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II.

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12 December 2020

Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2.

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12 December 2020

Polyphenols and disease risk in epidemiologic studies

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12 December 2020

ADMA and oxidative stress

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12 December 2020

Influence of Folic Acid on Postprandial Endothelial Dysfunction

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12 December 2020

10.1007/S00424-010-0808-2

Identifiers

DOI

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release_dpi35lhyczcthku3zit6evbs4u

22 August 2017

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Fatcat

https://api.fatcat.wiki/v0/release/dpi35lhyczcthku3zit6evbs4u

24 November 2022

mapped directly with Wikidata item

PubMed ID

20306272

1 reference

PubMed ID

20306272