SHIP2 and its involvement in various diseases (Q37763949)

22 August 2017

1 reference

title

SHIP2 and its involvement in various diseases (English)

1 reference

22 August 2017

Akira Suwa

1

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22 August 2017

Takeshi Kurama

series ordinal

2

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22 August 2017

Teruhiko Shimokawa

series ordinal

3

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22 August 2017

language of work or name

English

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publication date

1 July 2010

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Expert Opinion on Therapeutic Targets

22 August 2017

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22 August 2017

14

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22 August 2017

727-737

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22 August 2017

7

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Phosphoinositides in cell regulation and membrane dynamics

22 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

AKT/PKB signaling: navigating downstream

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Phosphatidylinositol (3,4,5)P3 is essential but not sufficient for protein kinase B (PKB) activation; phosphatidylinositol (3,4)P2 is required for PKB phosphorylation at Ser-473: studies using cells from SH2-containing inositol-5-phosphatase knockou

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Identification of a second SH2-domain-containing protein closely related to the phosphatidylinositol polyphosphate 5-phosphatase SHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SH2-containing 5'-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The c-Cbl-associated protein and c-Cbl are two new partners of the SH2-containing inositol polyphosphate 5-phosphatase SHIP2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SHIP2 interaction with the cytoskeletal protein Vinexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The docking properties of SHIP2 influence both JIP1 tyrosine phosphorylation and JNK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SH2-containing inositol 5'-phosphatase SHIP2 associates with the p130(Cas) adapter protein and regulates cellular adhesion and spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The SH2-domian-containing inositol 5-phosphatase (SHIP)-2 binds to c-Met directly via tyrosine residue 1356 and involves hepatocyte growth factor (HGF)-induced lamellipodium formation, cell scattering and cell spreading

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

NMR Studies of a Heterotypic Sam−Sam Domain Association: The Interaction between the Lipid Phosphatase Ship2 and the EphA2 Receptor † , ‡

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The Src homology 2 domain containing inositol 5-phosphatase SHIP2 is recruited to the epidermal growth factor (EGF) receptor and dephosphorylates phosphatidylinositol 3,4,5-trisphosphate in EGF-stimulated COS-7 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Enteropathogenic Escherichia coli recruits the cellular inositol phosphatase SHIP2 to regulate actin-pedestal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Inositol phosphates: proliferation, metabolism and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The termination of PI3K signalling by SHIP1 and SHIP2 inositol 5-phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Vinexin beta regulates the phosphorylation of epidermal growth factor receptor on the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The SH2 domain containing inositol 5-phosphatase SHIP2 controls phosphatidylinositol 3,4,5-trisphosphate levels in CHO-IR cells stimulated by insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The control of phosphatidylinositol 3,4-bisphosphate concentrations by activation of the Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, SHIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Specific tyrosine phosphorylations mediate signal-dependent stimulation of SHIP2 inositol phosphatase activity, while the SH2 domain confers an inhibitory effect to maintain the basal activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The mouse SHIP2 (Inppl1) gene: complementary DNA, genomic structure, promoter analysis, and gene expression in the embryo and adult mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The SH2 domains of inositol polyphosphate 5-phosphatases SHIP1 and SHIP2 have similar ligand specificity but different binding kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Insulin signalling and the regulation of glucose and lipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

IRS proteins and the common path to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Role of protein kinase B in insulin-regulated glucose uptake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Regulating Glut4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

PTEN and SHIP2 regulates PI3K/Akt pathway through focal adhesion kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Structure, regulation and function of PKB/AKT--a major therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SH2-containing inositol phosphatase 2 predominantly regulates Akt2, and not Akt1, phosphorylation at the plasma membrane in response to insulin in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The lipid phosphatase SHIP2 controls insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Phox2 genes - from patterning to connectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Absence of the lipid phosphatase SHIP2 confers resistance to dietary obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Impact of transgenic overexpression of SH2-containing inositol 5'-phosphatase 2 on glucose metabolism and insulin signaling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Reversal of denervation-induced insulin resistance by SHIP2 protein synthesis blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The gene INPPL1, encoding the lipid phosphatase SHIP2, is a candidate for type 2 diabetes in rat and man

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Association of SH2-containing inositol phosphatase 2 with the insulin resistance of diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Polymorphisms in type II SH2 domain-containing inositol 5-phosphatase (INPPL1, SHIP2) are associated with physiological abnormalities of the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Impact of SRC homology 2-containing inositol 5'-phosphatase 2 gene polymorphisms detected in a Japanese population on insulin signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Association of SH-2 containing inositol 5'-phosphatase 2 gene polymorphisms and hyperglycemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Discovery and functional characterization of a novel small molecule inhibitor of the intracellular phosphatase, SHIP2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Phosphoinositol phosphatase SHIP2 promotes cancer development and metastasis coupled with alterations in EGF receptor turnover.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Spatial sensing in fibroblasts mediated by 3' phosphoinositides

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Cell biology of the movement of breast cancer cells: intracellular signalling and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Evolution of cell interactions with extracellular matrix during carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The Walter Herbert Lecture. Control of cell motility and tumour invasion by extracellular matrix interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Differential regulation of EphA2 in normal and malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

EphA2 receptor tyrosine kinase as a promising target for cancer therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

5' phospholipid phosphatase SHIP-2 causes protein kinase B inactivation and cell cycle arrest in glioblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The Akt kinases: isoform specificity in metabolism and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Dual role of SRC homology domain 2-containing inositol phosphatase 2 in the regulation of platelet-derived growth factor and insulin-like growth factor I signaling in rat vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

SHIP2 overexpression strongly reduces the proliferation rate of K562 erythroleukemia cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

MicroRNA expression profiles in head and neck cancer cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Micro-RNA profiling in kidney and bladder cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

MicroRNA signatures in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

MicroRNA-205 inhibits tumor cell migration through down-regulating the expression of the LDL receptor-related protein 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Suppression of cell growth and invasion by miR-205 in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The SH2 domain-containing 5-phosphatase SHIP2 is expressed in the germinal layers of embryo and adult mouse brain: increased expression in N-CAM-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Role for neuronal insulin resistance in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The role of insulin receptor signaling in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Smooth muscle cell phenotypes in atherosclerotic lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Stability and instability: two faces of coronary atherosclerosis. The Paul Dudley White Lecture 1995.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The insulin-like growth factor axis: A review of atherosclerosis and restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Deletion of the PDGFR-beta gene affects key fibroblast functions important for wound healing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Suppression of endothelial cell apoptosis by high density lipoproteins (HDL) and HDL-associated lysosphingolipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

The role of apolipoprotein E in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

APOE-4 genotype and neurophysiological vulnerability to Alzheimer's and cognitive aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2010.492780

10.1517/14728222.2010.492780

21 January 2018

Identifiers

DOI

1 reference

22 August 2017

1 reference