Histone methyltransferases: regulation of transcription and contribution to human disease (Q37780469)

23 August 2017

1 reference

title

Histone methyltransferases: regulation of transcription and contribution to human disease (English)

1 reference

23 August 2017

1

Keisuke Nimura

1 reference

23 August 2017

Kiyoe Ura

2

1 reference

PubMed ID

20714703

23 August 2017

Yasufumi Kaneda

series ordinal

3

1 reference

23 August 2017

17 August 2010

1 reference

Journal of Molecular Medicine

23 August 2017

1 reference

23 August 2017

88

1 reference

23 August 2017

12

1 reference

23 August 2017

1213-1220

1 reference

https://scigraph.springernature.com/pub.10.1007/s00109-010-0668-4

23 August 2017

0 references

cites work

Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against human AML cells

1 reference

Crossref

https://api.crossref.org/works/10.1007%2FS00109-010-0668-4

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4

21 January 2018

1 reference

12 December 2020

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

1 reference

12 December 2020

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

1 reference

12 December 2020

Epigenetic inactivation of the Sotos overgrowth syndrome gene histone methyltransferase NSD1 in human neuroblastoma and glioma

1 reference

12 December 2020

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2

1 reference

12 December 2020

Histone H3 Lys 4 methylation: caught in a bind?

1 reference

12 December 2020

Identification and characterization of a novel human histone H3 lysine 36-specific methyltransferase

1 reference

12 December 2020

NUP98 is fused to the NSD3 gene in acute myeloid leukemia associated with t(8;11)(p11.2;p15).

1 reference

12 December 2020

Identification and characterization of Smyd2: a split SET/MYND domain-containing histone H3 lysine 36-specific methyltransferase that interacts with the Sin3 histone deacetylase complex

1 reference

12 December 2020

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

1 reference

12 December 2020

Arginine methylation an emerging regulator of protein function

1 reference

12 December 2020

NSD3, a new SET domain-containing gene, maps to 8p12 and is amplified in human breast cancer cell lines

1 reference

12 December 2020

NSD1 is essential for early post-implantation development and has a catalytically active SET domain

1 reference

12 December 2020

Cotranscriptional set2 methylation of histone H3 lysine 36 recruits a repressive Rpd3 complex

1 reference

12 December 2020

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

1 reference

12 December 2020

Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription

1 reference

12 December 2020

Control of cognition and adaptive behavior by the GLP/G9a epigenetic suppressor complex

1 reference

12 December 2020

Distinct transcriptional outputs associated with mono- and dimethylated histone H3 arginine 2.

1 reference

12 December 2020

LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability

1 reference

12 December 2020

SmyD1, a histone methyltransferase, is required for myofibril organization and muscle contraction in zebrafish embryos.

1 reference

12 December 2020

Mouse models of Wolf-Hirschhorn syndrome

1 reference

12 December 2020

A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex.

1 reference

12 December 2020

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

1 reference

12 December 2020

Global analysis of H3K4 methylation defines MLL family member targets and points to a role for MLL1-mediated H3K4 methylation in the regulation of transcriptional initiation by RNA polymerase II.

1 reference

12 December 2020

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET.

1 reference

12 December 2020

Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3.

1 reference

12 December 2020

The t(4;14) translocation in myeloma dysregulates both FGFR3 and a novel gene, MMSET, resulting in IgH/MMSET hybrid transcripts

1 reference

12 December 2020

Reduced exploration, increased anxiety, and altered social behavior: Autistic-like features of euchromatin histone methyltransferase 1 heterozygous knockout mice.

1 reference

12 December 2020

PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation

1 reference

12 December 2020

Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks

1 reference

12 December 2020

Regulation of p53 activity through lysine methylation

1 reference

12 December 2020

SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

1 reference

12 December 2020

Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes

1 reference

12 December 2020

Protein arginine methyltransferases: evolution and assessment of their pharmacological and therapeutic potential

1 reference

12 December 2020

Mapping the Wolf-Hirschhorn syndrome phenotype outside the currently accepted WHS critical region and defining a new critical region, WHSCR-2.

1 reference

12 December 2020

High-resolution profiling of histone methylations in the human genome

1 reference

12 December 2020

MLL targets SET domain methyltransferase activity to Hox gene promoters

1 reference

12 December 2020

1 reference

12 December 2020

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases

1 reference

12 December 2020

L3MBTL1, a histone-methylation-dependent chromatin lock

1 reference

12 December 2020

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression

1 reference

12 December 2020

Haploinsufficiency of NSD1 causes Sotos syndrome

1 reference

12 December 2020

The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains

1 reference

12 December 2020

Regulation of NF-kappaB by NSD1/FBXL11-dependent reversible lysine methylation of p65.

1 reference

12 December 2020

The histone methyltransferase, NSD2, enhances androgen receptor-mediated transcription

1 reference

12 December 2020

ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation

1 reference

12 December 2020

The ankyrin repeats of G9a and GLP histone methyltransferases are mono- and dimethyllysine binding modules

1 reference

12 December 2020

A transcript map of the newly defined 165 kb Wolf-Hirschhorn syndrome critical region

1 reference

12 December 2020

Chromatin modifications and their function

1 reference

12 December 2020

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

1 reference

12 December 2020

Arginine methylation of the histone H3 tail impedes effector binding

1 reference

12 December 2020

Inactivation of a histone methyltransferase by mutations in human cancers

1 reference

12 December 2020

Molecular regulation of H3K4 trimethylation by ASH2L, a shared subunit of MLL complexes

1 reference

12 December 2020

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

1 reference

12 December 2020

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

1 reference

12 December 2020

Mutations in the JARID1C gene, which is involved in transcriptional regulation and chromatin remodeling, cause X-linked mental retardation

1 reference

12 December 2020

hDOT1L links histone methylation to leukemogenesis

1 reference

12 December 2020

Covalent modifications of histones during development and disease pathogenesis

1 reference

12 December 2020

Genotype-phenotype correlation in 21 patients with Wolf-Hirschhorn syndrome using high resolution array comparative genome hybridisation (CGH).

1 reference

12 December 2020

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

1 reference

12 December 2020

Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylation

1 reference

12 December 2020

PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks

1 reference

12 December 2020

Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators

1 reference

12 December 2020

Regulation of histone methylation by demethylimination and demethylation

1 reference

12 December 2020

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

1 reference

12 December 2020

Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development

1 reference

12 December 2020

The etiology of Wolf-Hirschhorn syndrome

1 reference

12 December 2020

WHSC1, a 90 kb SET domain-containing gene, expressed in early development and homologous to a Drosophila dysmorphy gene maps in the Wolf-Hirschhorn syndrome critical region and is fused to IgH in t(4;14) multiple myeloma

1 reference

12 December 2020

Tudor, MBT and chromo domains gauge the degree of lysine methylation

1 reference

12 December 2020

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

1 reference

12 December 2020

The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure

1 reference

12 December 2020

The diverse functions of histone lysine methylation

1 reference

12 December 2020

Roles of the EZH2 histone methyltransferase in cancer epigenetics

1 reference

12 December 2020

Zinc finger protein Wiz links G9a/GLP histone methyltransferases to the co-repressor molecule CtBP

1 reference

12 December 2020

Nizp1, a novel multitype zinc finger protein that interacts with the NSD1 histone lysine methyltransferase through a unique C2HR motif

1 reference

12 December 2020

Regulation of alternative splicing by histone modifications

1 reference

12 December 2020

The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate

1 reference

12 December 2020

Disruption of the gene Euchromatin Histone Methyl Transferase1 (Eu-HMTase1) is associated with the 9q34 subtelomeric deletion syndrome.

1 reference

12 December 2020

Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

1 reference

12 December 2020

Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis

1 reference

12 December 2020

Frequency of NUP98-NSD1 fusion transcript in childhood acute myeloid leukaemia

1 reference

12 December 2020

DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation.

1 reference

12 December 2020

The role of chromatin during transcription

1 reference

12 December 2020

Loss-of-function mutations in euchromatin histone methyl transferase 1 (EHMT1) cause the 9q34 subtelomeric deletion syndrome

1 reference

12 December 2020

Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9

1 reference

12 December 2020

10.1007/S00109-010-0668-4

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

20714703