Critical review of preclinical approaches to evaluate the potential of immunosuppressive drugs to influence human neoplasia (Q37795414)

23 August 2017

Critical review of preclinical approaches to evaluate the potential of immunosuppressive drugs to influence human neoplasia (English)

1 reference

23 August 2017

Peter J Bugelski

1

1 reference

23 August 2017

Amy Volk

2

1 reference

23 August 2017

Mindi R Walker

3

1 reference

23 August 2017

John H Krayer

4

1 reference

23 August 2017

Pauline Martin

5

1 reference

23 August 2017

Jacques Descotes

6

1 reference

23 August 2017

1 September 2010

1 reference

International Journal of Toxicology

23 August 2017

1 reference

23 August 2017

29

1 reference

23 August 2017

5

1 reference

23 August 2017

435-466

1 reference

Experiences with renal homotransplantation in the human: report of nine cases

23 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Biological effects of cyclosporin A: A new antilymphocytic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Newer therapeutic approaches for systemic lupus erythematosus: immunosuppressive agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Calcineurin inhibitors and rapamycin: cancer protection or promotion?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The carcinogenicity of ciclosporin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cancer immunoediting: from immunosurveillance to tumor escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The immune system--is it relevant to cancer development, progression and treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immune surveillance of tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppressive drugs and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Supplement to the Carcinogenic Potency Database (CPDB): results of animal bioassays published in the general literature through 1997 and by the National Toxicology Program in 1997-1998.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mechanisms of non-genotoxic carcinogens and importance of a weight of evidence approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Genetic instabilities in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immune surveillance: a balance between protumor and antitumor immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The flip side of immune surveillance: immune dependency

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppressive strategies that are mediated by tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Primary immunodeficiency diseases and cancer: the immunodeficiency-cancer registry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Malignancy after solid organ transplantation: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Malignancy after heart transplantation: incidence, prognosis and risk factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunodeficiency-associated lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Epstein-Barr virus-associated lymphoproliferative disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Spontaneous remission of "methotrexate-associated lymphoproliferative disorders" after discontinuation of immunosuppressive treatment for autoimmune disease. Review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Post-transplant lymphoproliferative disorders: molecular basis of disease histogenesis and pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Infectious aetiology of Hodgkin and non-Hodgkin lymphomas: a review of the epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppressive therapy and post-transplant malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Skin cancer in organ transplant recipients--where do we stand today?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Risk of nonmelanoma skin cancer with azathioprine use.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppression and squamous cell carcinoma: a focus on solid organ transplant recipients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Role of viruses in the development of squamous cell cancer and melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cutaneous squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Evolving epidemiology of malignancies in HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

HIV-associated Kaposi sarcoma and gender

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Chronic inflammation: a common and important factor in the pathogenesis of neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Epstein-Barr virus (EBV)-positive lymphoproliferations in post-transplant patients show immunoglobulin V gene mutation patterns suggesting interference of EBV with normal B cell differentiation processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

HIV-associated lymphomas and gamma-herpesviruses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Reversal of ultraviolet radiation-induced immune suppression by recombinant interleukin-12: suppression of cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Non-melanoma skin cancer: importance of gender, immunosuppressive status and vitamin D.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

UV-induced immune suppression and photocarcinogenesis: chemoprevention by dietary botanical agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Toxic effects of ultraviolet radiation on the skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Induction of squamous cell carcinoma in p53-deficient mice after ultraviolet irradiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Inflammation and cancer: back to Virchow?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Points to consider on the statistical analysis of rodent cancer bioassay data when incorporating historical control data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Update on genotoxicity and carcinogenicity testing of 472 marketed pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Implications of the lack of accuracy of the lifetime rodent bioassay for predicting human carcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Data quality in predictive toxicology: reproducibility of rodent carcinogenicity experiments

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Neonatal mouse model: review of methods and results

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Role of natural killer cells in control of cancer metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Neonatal mouse assay for tumorigenicity: alternative to the chronic rodent bioassay.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Background and framework for ILSI's collaborative evaluation program on alternative models for carcinogenicity assessment. International Life Sciences Institute

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Ras family genes: an interesting link between cell cycle and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The Tg.AC (v-Ha-ras) transgenic mouse: nature of the model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Behavioral and immune changes in v-Ha-ras transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Tg.AC genetically altered mouse: assay working group overview of available data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The rasH2 transgenic mouse: nature of the model and mechanistic studies on tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

CB6F1-rasH2 mouse: overview of available data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Interlaboratory comparison of the CB6F1-Tg rasH2 rapid carcinogenicity testing model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The nature of the heterozygous Trp53 knockout model for identification of mutagenic carcinogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

P53+/- hemizygous knockout mouse: overview of available data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immune selection in neoplasia: towards a microevolutionary model of cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Non-melanoma skin cancer: what drives tumor development and progression?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Influence of total dose and dose rate in carcinogenicity studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Carcinogen-induced inflammation and immunosuppression are enhanced in xeroderma pigmentosum group A model mice associated with hyperproduction of prostaglandin E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effect of Cyclosporine on 3-Methylcholanthrene-Induced Carcinogenesis and Immune Responses in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Diversity of the promoting action of cyclosporine on the induction of murine lymphoid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Topical application of the immunosuppressant tacrolimus accelerates carcinogenesis in mouse skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Initiation-promotion model for assessment of carcinogenicity: medium-term liver bioassay in rats for rapid detection of carcinogenic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Prevention of oncogenic viral infections in mice with CGP 11637, a synthetic muramyl dipeptide analog

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Treatment of premalignancy: prevention of lymphoma in radiation leukemia virus-inoculated mice by cyclosporin A and immunotoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

All-trans retinoic acid protects against conversion of chemically induced and ultraviolet B radiation-induced skin papillomas to carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Ultraviolet radiation and immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Integrative radiation carcinogenesis: interactions between cell and tissue responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The road to linearity: why linearity at low doses became the basis for carcinogen risk assessment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Radiation carcinogenesis in mouse thymic lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Linearity vs non-linearity of dose response for radiation carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Radiation leukemogenesis in mice: loss of PU.1 on chromosome 2 in CBA and C57BL/6 mice after irradiation with 1 GeV/nucleon 56Fe ions, X rays or gamma Rays. Part II. Theoretical considerations based on microdosimetry and the initial induction of chr

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Facilitation of nodal metastasis from a non-immunogenic murine carcinoma by previous whole-body irradiation of tumour recipients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Differential gene signatures in rat mammary tumors induced by DMBA and those induced by fractionated gamma radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Radiation-induced mammary carcinogenesis in rodent models: what's different from chemical carcinogenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Increased skin carcinogenesis in caspase-activated DNase knockout mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cyclosporine promotes the induction of thymic lymphomas in C57BL/6 mice initiated by a single dose of gamma-radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Anti-rejection drug treatment increases basal cell carcinoma burden in Ptch1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Topical thymidine dinucleotide treatment reduces development of ultraviolet-induced basal cell carcinoma in Ptch-1+/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The Hedgehog receptor Patched controls lymphoid lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Maximizing mouse cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Tumor challenges in immunotoxicity testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Application of tumor, bacterial and parasite susceptibility assays to study immune alterations induced by environmental chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cancer in mice: effects of prednisolone or mepacrine alone and with cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cyclosporine induces cancer progression by a cell-autonomous mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

From clinical to human toxicology: linking animal research and risk assessment in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Concordance of the toxicity of pharmaceuticals in humans and in animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Species differences in the structure and function of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Species comparison of anatomical and functional immune system development

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Of mice and humans: how good are HLA transgenic mice as a model of human immune responses?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

U.S. Food and Drug Administration perspective of the inclusion of effects of low-level exposures in safety and risk assessment

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Assessment of immunosuppressant drug carcinogenicity: standard and alternative animal models

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Failure of immunosuppressive drug levels to predict T-cell reactivity in pediatric transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Hazard identification and risk assessment for biologics targeting the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rituximab: in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Duration of chronic toxicity studies for biotechnology-derived pharmaceuticals: is 6 months still appropriate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Nonhuman primate models to evaluate vaccine safety and immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Spontaneous neoplasms observed in cynomolgus monkeys (Macaca fascicularis) during a 15-year period.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Posttransplant lymphoproliferative disorder associated with an Epstein-Barr-related virus in cynomolgus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Tumorigenesis in High-Dose Total Body Irradiated Rhesus Monkeys—A Life Span Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Experimental Carcinoma of Liver in Macaque Monkeys Exposed to Diethylnitrosamine and Hepatitis B Virus2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Chemical carcinogenesis studies in nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effects of dexamethasone on tumor-induced brain edema and its distribution in the brain of monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Brain-tumor chemotherapy. Pharmacological principles derived from a monkey brain-tumor model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Alternative strategies for toxicity testing of species-specific biopharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Safety assessment of biopharmaceuticals: Japanese perspective on ICH S6 guideline maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Atypical serum immunofixation patterns frequently emerge in immunomodulatory therapy and are associated with a high degree of response in multiple myeloma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Fourth biannual report of the Cochrane Haematological Malignancies Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppression and cancer: the ciclosporin case

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Squamous cell carcinoma arising in pemphigus vulgaris during immunosuppressive therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Human papillomavirus type 16 associated with oral squamous carcinoma in a cardiac transplant recipient

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Plasma cell leukemia occurring in a patient with thrombocythemia treated with hydroxyurea and busulphan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Fatal donor-derived Epstein-Barr virus-associated post-transplant lymphoproliferative disorder following reduced intensity volunteer-unrelated bone marrow transplant for myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Monoclonal Epstein-Barr virus-related lymphoproliferative disorder following adult acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Lymphoma in patients with rheumatoid arthritis: what is the evidence of a link with methotrexate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

T-cell lymphoproliferative disorder following mycophenolate treatment for myasthenia gravis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Epstein Barr virus-associated primary CNS lymphomas in elderly patients on immunosuppressive medications

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Squamous cell carcinomas in 2 patients with diffuse scleroderma treated with mycophenolate mofetil

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Posttransplant lymphoproliferative disorders after renal transplantation in the United States in era of modern immunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The carcinogenic potential of tacrolimus ointment beyond immune suppression: a hypothesis creating case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cancer after renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Kaposi sarcoma in transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Kaposi's sarcoma in renal transplant recipients--the impact of proliferation signal inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor induction by the carcinogen N-hydroxy-N-2-fluorenylacetamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effect of cyclosporin A and tacrolimus on sister chromatid exchange frequency in renal transplant patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Role of reactive oxygen species in cell toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

IL-18 reduces ultraviolet radiation-induced DNA damage and thereby affects photoimmunosuppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

JAK pathway induction of c-Myc critical to IL-5 stimulation of cell proliferation and inhibition of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Regulation of growth-related genes by interleukin-6 in murine myeloma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Natural killer cells in innate immunity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Chemokines: key players in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

A two-way interaction between hepatocyte growth factor and interleukin-6 in tissue invasion of lung cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Role of tumor-associated macrophages in tumor progression and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cytokines in breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Microenvironmental regulation of metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Tumor cell responses to IFNgamma affect tumorigenicity and response to IL-12 therapy and antiangiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

DNA repair-deficient Xpa/p53 knockout mice are sensitive to the non-genotoxic carcinogen cyclosporine A: escape of initiated cells from immunosurveillance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Reduction of primordial follicles caused by maternal treatment with busulfan promotes endometrial adenocarcinoma development in donryu rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Immune-cell system provides the development of extraneural tumors in the ethyl-nitrosourea model of neurocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Enhancement of chemically induced bladder carcinoma by cyclosporin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effect of cyclosporine on carcinogenesis induced in rats by N-methyl-N'-nitro-N-nitrosoguanidine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Cyclosporine stimulates hepatocyte proliferation and accelerates development of hepatocellular carcinomas in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effects of oral administration of ciclosporin A on skin carcinogenesis: a study using the two-stage carcinogenesis protocol in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Long-term carcinogenicity of cyclophosphamide in two mouse strains with different spontaneous leukemia incidence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Osteomas in OF-1 mice: no alteration in biologic behavior during long-term treatment with cyclosporine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Topical pimecrolimus and tacrolimus do not accelerate photocarcinogenesis in hairless mice after UVA or simulated solar radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Dexamethasone inhibits glioma-induced formation of capillary like structures in vitro and angiogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mycophenolate mofetil inhibits tumor growth and angiogenesis in vitro but has variable antitumor effects in vivo, possibly related to bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Mycophenolate mofetil attenuates Walker's tumor growth when used alone, but the effect is lost when associated with cyclosporine

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effect of cyclosporin A on the growth and spontaneous metastasis of syngeneic animal tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Do the Immunosuppressive Drugs used as Treatment for Graft-versus-host Disease Directly Inhibit Lymphoid Tumor Cell Growth?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Inhibition of tumor growth in immunocompromised hosts by restoring type-2 immunity using infusion of G-CSF-treated allogeneic CD8+ leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

RAD inhibition of sarcoma growth: implications for laryngeal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Enhancement by drugs of metastatic lung nodule formation after intravenous tumour cell injection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Enhanced experimental metastatic capacity of a murine melanoma following pre-treatment with anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Low-dose methotrexate inhibits lung metastasis and lengthens survival in rat osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Tacrolimus enhances transforming growth factor-beta1 expression and promotes tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Glucocorticoids suppress tumor angiogenesis and in vivo growth of prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

In vivo effects of dexamethasone on the tumor growth of glucocorticoid-sensitive Fu5-derived rat hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Busulphan is active against neuroblastoma and medulloblastoma xenografts in athymic mice at clinically achievable plasma drug concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Comparison of 131I-labelled anti-episialin 139H2 with cisplatin, cyclophosphamide or external-beam radiation for anti-tumor efficacy in human ovarian cancer xenografts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

In vitro and in vivo antitumor activity of a novel immunomodulatory drug, leflunomide: mechanisms of action

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Leflunomide reduces the angiogenesis score and tumor growth of subcutaneously implanted colon carcinoma cells in the mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Origin of organisms infecting ventricular shunts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Antiproliferative and apoptotic effects of mycophenolic acid in human B-cell non-Hodgkin lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

The immunosuppressive macrolide RAD inhibits growth of human Epstein-Barr virus-transformed B lymphocytes in vitro and in vivo: A potential approach to prevention and treatment of posttransplant lymphoproliferative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Pivotal role of mTOR signaling in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

Role of immunosuppression in recurrence after liver transplantation for diethylnitrosamine-induced tumors in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1091581810374654

21 January 2018

Identifiers

DOI

10.1177/1091581810374654

1 reference

23 August 2017

1 reference