Antigen-driven T-cell repertoire selection during adaptive immune responses (Q37801271)

23 August 2017

title

Antigen-driven T-cell repertoire selection during adaptive immune responses (English)

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23 August 2017

author name string

Christina K Baumgartner

series ordinal

1

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23 August 2017

Laurent P Malherbe

series ordinal

2

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23 August 2017

publication date

19 October 2010

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Immunology & Cell Biology

23 August 2017

published in

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23 August 2017

volume

89

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23 August 2017

issue

1

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23 August 2017

page(s)

54-59

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https://scigraph.springernature.com/pub.10.1038/icb.2010.117

23 August 2017

exact match

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cites work

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The dominant role of CD8+ dendritic cells in cross-presentation is not dictated by antigen capture

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Found in translation: the human equivalent of mouse CD8+ dendritic cells

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Human CD141+ (BDCA-3)+ dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens.

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Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells

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Skin-derived dendritic cells induce potent CD8(+) T cell immunity in recombinant lentivector-mediated genetic immunization

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Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo.

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Distinct migrating and nonmigrating dendritic cell populations are involved in MHC class I-restricted antigen presentation after lung infection with virus

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Clearance of influenza virus from the lung depends on migratory langerin+CD11b- but not plasmacytoid dendritic cells

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Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

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Migratory Dendritic Cells Transfer Antigen to a Lymph Node-Resident Dendritic Cell Population for Efficient CTL Priming

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T-cell epitope mapping

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Antigen presentation to naive CD4 T cells in the lymph node.

21 January 2018

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CD4 T cells integrate signals delivered during successive DC encounters in vivo

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Migratory and lymphoid-resident dendritic cells cooperate to efficiently prime naive CD4 T cells

21 January 2018

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GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.

21 January 2018

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Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses

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Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells.

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Antigen persistence is required throughout the expansion phase of a CD4(+) T cell response

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Kinetic proofreading in T-cell receptor signal transduction

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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

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Evolution of antigen-specific T cell receptors in vivo: preimmune and antigen-driven selection of preferred complementarity-determining region 3 (CDR3) motifs

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Evidence for a TCR affinity threshold delimiting maximal CD8 T cell function.

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Antigen-specific memory B cell development

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T Cell Receptor Recognition Motifs Govern Immune Escape Patterns in Acute SIV Infection

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Dependence of T cell antigen recognition on T cell receptor-peptide MHC confinement time

21 January 2018

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The kinetics of two-dimensional TCR and pMHC interactions determine T-cell responsiveness.

21 January 2018

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Fast on-rates allow short dwell time ligands to activate T cells

21 January 2018

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Complete but curtailed T-cell response to very low-affinity antigen

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Apoptosis threshold set by Noxa and Mcl-1 after T cell activation regulates competitive selection of high-affinity clones.

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Interactions between MHC molecules and co-receptors of the TCR.

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Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor

21 January 2018

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CD4 enhances T cell sensitivity to antigen by coordinating Lck accumulation at the immunological synapse

21 January 2018

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Interplay between TCR affinity and necessity of coreceptor ligation: high-affinity peptide-MHC/TCR interaction overcomes lack of CD8 engagement

21 January 2018

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Peripheral "CD8 tuning" dynamically modulates the size and responsiveness of an antigen-specific T cell pool in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Avidity for antigen shapes clonal dominance in CD8+ T cell populations specific for persistent DNA viruses

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

CD4 promotes breadth in the TCR repertoire

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Peptide-MHC class II complex stability governs CD4 T cell clonal selection

21 January 2018

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An inverse relationship between T cell receptor affinity and antigen dose during CD4(+) T cell responses in vivo and in vitro

21 January 2018

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Antigen dose governs the shaping of CTL repertoires in vitro and in vivo

21 January 2018

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Vaccine adjuvants alter TCR-based selection thresholds.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Lymphoid reservoirs of antigen-specific memory T helper cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Diversity of the CD8+ T cell repertoire elicited against an immunodominant epitope does not depend on the context of infection

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Structural determinants of T-cell receptor bias in immunity

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

A structural basis for immunodominant human T cell receptor recognition

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

CTL recognition of a bulged viral peptide involves biased TCR selection

21 January 2018

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Constraints within major histocompatibility complex class I restricted peptides: Presentation and consequences for T-cell recognition

21 January 2018

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21 January 2018

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21 January 2018

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Stability and diversity of T cell receptor repertoire usage during lymphocytic choriomeningitis virus infection of mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

A fractal clonotype distribution in the CD8+ memory T cell repertoire could optimize potential for immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Selection of T cell clones expressing high-affinity public TCRs within Human cytomegalovirus-specific CD8 T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Rapid CD8+ T cell repertoire focusing and selection of high-affinity clones into memory following primary infection with a persistent human virus: human cytomegalovirus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Clonal repertoires of virus-specific CD8+ T lymphocytes are shared in mucosal and systemic compartments during chronic simian immunodeficiency virus infection in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Epitope dominance, competition and T cell affinity maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

T cells down-modulate peptide-MHC complexes on APCs in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Induction and evolution of cytomegalovirus-specific CD4+ T cell clonotypes in rhesus macaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Antigen-specific development of primary and memory T cells in vivo.

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

Rapid culling of the CD4+ T cell repertoire in the transition from effector to memory

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

The T cell repertoire in infection and vaccination: implications for control of persistent viruses

21 January 2018

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Selective activation and expansion of high-affinity CD4+ T cells in resistant mice upon infection with Leishmania major.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Public clonotype usage identifies protective Gag-specific CD8+ T cell responses in SIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Functional implications of T cell receptor diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Antigen presentation by dendritic cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Naïve CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

The CD8 response on autopilot.

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

In situ analysis reveals physical interactions between CD11b+ dendritic cells and antigen-specific CD4 T cells after subcutaneous injection of antigen

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Real-time manipulation of T cell-dendritic cell interactions in vivo reveals the importance of prolonged contacts for CD4+ T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

CD8+ T cell activation is governed by TCR-peptide/MHC affinity, not dissociation rate

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Complex T cell memory repertoires participate in recall responses at extremes of antigenic load

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https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR

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https://api.crossref.org/works/10.1038%2FICB.2010.117

7 January 2021

Identifiers

DOI

10.1038/ICB.2010.117

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Dimensions Publication ID

23 August 2017

1023310917

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