Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy (Q37819453)

23 August 2017

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title

Recent insights into diabetic renal injury from the db/db mouse model of type 2 diabetic nephropathy (English)

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23 August 2017

G H Tesch

1

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PubMed ID

21147843

23 August 2017

A K H Lim

series ordinal

2

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PubMed ID

21147843

23 August 2017

language of work or name

1 reference

8 December 2010

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American Journal of Physiology - Renal Physiology

23 August 2017

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23 August 2017

300

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23 August 2017

F301-10

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23 August 2017

2

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Abnormal p38 mitogen-activated protein kinase signalling in human and experimental diabetic nephropathy

23 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

The AGE inhibitor pyridoxamine inhibits lipemia and development of renal and vascular disease in Zucker obese rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Leptin regulates neointima formation after arterial injury through mechanisms independent of blood pressure and the leptin receptor/STAT3 signaling pathways involved in energy balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Attenuation of interstitial fibrosis and tubular apoptosis in db/db transgenic mice overexpressing catalase in renal proximal tubular cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Omacor, n-3 polyunsaturated fatty acid, attenuated albuminuria and renal dysfunction with decrease of SREBP-1 expression and triglyceride amount in the kidney of type II diabetic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Macrophages in mouse type 2 diabetic nephropathy: correlation with diabetic state and progressive renal injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Monocyte chemoattractant protein-1-induced tissue inflammation is critical for the development of renal injury but not type 2 diabetes in obese db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Intercellular adhesion molecule-1 deficiency is protective against nephropathy in type 2 diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

A susceptibility gene for kidney disease in an obese mouse model of type II diabetes maps to chromosome 8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Prevention of diabetic nephropathy in db/db mice with glycated albumin antagonists. A novel treatment strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Overexpression of Cu2+/Zn2+ superoxide dismutase protects against early diabetic glomerular injury in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

The effect of salt on renal damage in eNOS-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Attenuation of renal injury in db/db mice overexpressing superoxide dismutase: evidence for reduced superoxide-nitric oxide interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Aliskiren enhances protective effects of valsartan against type 2 diabetic nephropathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Bilirubin and biliverdin protect rodents against diabetic nephropathy by downregulating NAD(P)H oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Renal failure increases cardiac histone h3 acetylation, dimethylation, and phosphorylation and the induction of cardiomyopathy-related genes in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

A PAI-1 mutant, PAI-1R, slows progression of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Inhibition of C-jun N-terminal kinase improves insulin sensitivity but worsens albuminuria in experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Soluble betaglycan reduces renal damage progression in db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Soluble Flt-1 gene therapy ameliorates albuminuria but accelerates tubulointerstitial injury in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Abnormal splicing of the leptin receptor in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Modulation of single-nephron GFR in the db/db mouse model of type 2 diabetes mellitus. II. Effects of renal mass reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Antibody blockade of c-fms suppresses the progression of inflammation and injury in early diabetic nephropathy in obese db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Role of MKK3-p38 MAPK signalling in the development of type 2 diabetes and renal injury in obese db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Diabetic eNOS knockout mice develop distinct macro- and microvascular complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Nilvadipine attenuates mesangial expansion and glomerular hypertrophy in diabetic db/db mice, a model for type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Reduction of diabetes-induced renal oxidative stress by a cantaloupe melon extract/gliadin biopolymers, oxykine, in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Critical role for osteopontin in diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Late onset of Ccl2 blockade with the Spiegelmer mNOX-E36-3'PEG prevents glomerulosclerosis and improves glomerular filtration rate in db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

The role of interstitial macrophages in nephropathy of type 2 diabetic db/db mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Prevention and reversal of diabetic nephropathy in db/db mice treated with alagebrium (ALT-711).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Oral administration of GW788388, an inhibitor of TGF-beta type I and II receptor kinases, decreases renal fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Inhibition of renin angiotensin system decreases renal protein oxidative damage in diabetic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Pirfenidone is renoprotective in diabetic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Podocytes produce homeostatic chemokine stromal cell-derived factor-1/CXCL12, which contributes to glomerulosclerosis, podocyte loss and albuminuria in a mouse model of type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Cardiovascular and autonomic phenotype of db/db diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

N-acetyl-seryl-aspartyl-lysyl-proline prevents renal insufficiency and mesangial matrix expansion in diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Hypertension and disrupted blood pressure circadian rhythm in type 2 diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

SMP-534 ameliorates progression of glomerular fibrosis and urinary albumin in diabetic db/db mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Renoprotection by rosiglitazone in accelerated type 2 diabetic nephropathy: Role of STAT1 inhibition and nephrin restoration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Macrophages and diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

RAGE drives the development of glomerulosclerosis and implicates podocyte activation in the pathogenesis of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Endothelial nitric oxide synthase deficiency produces accelerated nephropathy in diabetic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

Plasminogen activator inhibitor-1 deficiency has renal benefits but some adverse systemic consequences in diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00607.2010

10.1152/AJPRENAL.00607.2010

21 January 2018

Identifiers

DOI

1 reference

23 August 2017

1 reference

PubMed ID

21147843