Genome-wide association studies and Crohn's disease (Q37857566)

24 August 2017

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title

Genome-wide association studies and Crohn's disease (English)

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genome-wide association study

24 August 2017

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1

James C Lee

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24 August 2017

Miles Parkes

2

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24 August 2017

1 March 2011

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Briefings in functional genomics

24 August 2017

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24 August 2017

10

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24 August 2017

2

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24 August 2017

71-76

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Unravelling the pathogenesis of inflammatory bowel disease

24 August 2017

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genetics versus environment in inflammatory bowel disease: results of a British twin study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Familial occurrence of inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Activation of innate immune antiviral responses by Nod2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

The pathogen recognition receptor NOD2 regulates human FOXP3+ T cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

TL1A produced by lamina propria macrophages induces Th1 and Th17 immune responses in cooperation with IL-23 in patients with Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Human IRGM induces autophagy to eliminate intracellular mycobacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Virus-plus-susceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Interleukin-23 drives innate and T cell-mediated intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Common variants at five new loci associated with early-onset inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Use of sirolimus (rapamycin) to treat refractory Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Clinical patterns of familial inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Genomewide association study of leprosy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Absence of mutation in the NOD2/CARD15 gene among 483 Japanese patients with Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Contribution of IL23R but not ATG16L1 to Crohn's disease susceptibility in Koreans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBFGP%2FELR009

21 January 2018

Identifiers

DOI

10.1093/BFGP/ELR009

1 reference

24 August 2017

1 reference

PubMed ID

21436303