Dancing with the dead: Eph receptors and their kinase-null partners (Q37860149)

24 August 2017

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title

Dancing with the dead: Eph receptors and their kinase-null partners (English)

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24 August 2017

Luke Truitt

1

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24 August 2017

Andrew Freywald

series ordinal

2

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24 August 2017

publication date

1 April 2011

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Biochemistry and Cell Biology

24 August 2017

published in

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24 August 2017

volume

89

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24 August 2017

issue

2

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24 August 2017

page(s)

115-129

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Axon guidance molecules in vascular patterning

24 August 2017

cites work

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Coexpression of EphB4 and ephrinB2 in tumour advancement of ovarian cancers

21 January 2018

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Coexpression of EphB4 and ephrinB2 in tumor advancement of uterine cervical cancers

21 January 2018

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Tissue transglutaminase clusters soluble A-type ephrins into functionally active high molecular weight oligomers

21 January 2018

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Transcriptional switch of dormant tumors to fast-growing angiogenic phenotype

21 January 2018

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Eph and ephrin signaling in mammary gland morphogenesis and cancer

21 January 2018

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EphB receptor activity suppresses colorectal cancer progression

21 January 2018

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EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing.

21 January 2018

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Self-association studies on the EphB2 receptor SAM domain using analytical ultracentrifugation.

21 January 2018

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Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors

21 January 2018

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Loss of EphA2 receptor tyrosine kinase reduces ApcMin/+ tumorigenesis

21 January 2018

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Eph receptor tyrosine kinases in tumor and tumor microenvironment

21 January 2018

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The receptor tyrosine kinase EphA2 promotes mammary adenocarcinoma tumorigenesis and metastatic progression in mice by amplifying ErbB2 signaling

21 January 2018

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EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains

21 January 2018

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The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain

21 January 2018

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Distinct membrane compartmentalization and signaling of ephrin-A5 and ephrin-B1.

21 January 2018

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Activation of peripheral ephrinBs/EphBs signaling induces hyperalgesia through a MAPKs-mediated mechanism in mice

21 January 2018

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Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport

21 January 2018

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EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.

21 January 2018

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Compartmentalized signaling by GPI-anchored ephrin-A5 requires the Fyn tyrosine kinase to regulate cellular adhesion

21 January 2018

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Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis

21 January 2018

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Eph receptors and ephrin signaling pathways: a role in bone homeostasis

21 January 2018

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Bidirectional Eph-ephrin signaling during axon guidance

21 January 2018

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Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction

21 January 2018

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Regeneration-enhancing effects of EphA4 blocking peptide following corticospinal tract injury in adult rat spinal cord

21 January 2018

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Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport

21 January 2018

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Neural map specification by gradients

21 January 2018

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The ephrins and Eph receptors in neural development

21 January 2018

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Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic application

21 January 2018

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Transcriptional silencing of EphB6 receptor tyrosine kinase in invasive breast carcinoma cells and detection of methylated promoter by methylation specific PCR.

21 January 2018

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EphB6 receptor significantly alters invasiveness and other phenotypic characteristics of human breast carcinoma cells

21 January 2018

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Potential clinical relevance of Eph receptors and ephrin ligands expressed in prostate carcinoma cell lines.

21 January 2018

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Ryks: new partners for Wnts in the developing and regenerating nervous system

21 January 2018

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The kinase-null EphB6 receptor undergoes transphosphorylation in a complex with EphB1.

21 January 2018

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The EphB6 receptor inhibits JNK activation in T lymphocytes and modulates T cell receptor-mediated responses

21 January 2018

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EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes

21 January 2018

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Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer

21 January 2018

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EphA4 promotes cell proliferation and migration through a novel EphA4-FGFR1 signaling pathway in the human glioma U251 cell line

21 January 2018

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Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis

21 January 2018

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On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network

21 January 2018

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Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization.

21 January 2018

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Ephrin signaling: One raft to rule them all? One raft to sort them? One raft to spread their call and in signaling bind them?

21 January 2018

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Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.

21 January 2018

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Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB-induced Src phosphorylation and signaling

21 January 2018

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Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features

21 January 2018

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Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers

21 January 2018

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Revelations of the RYK receptor

21 January 2018

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Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

21 January 2018

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Retinal axon response to ephrin-as shows a graded, concentration-dependent transition from growth promotion to inhibition

21 January 2018

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Non-conventional Frizzled ligands and Wnt receptors.

21 January 2018

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Eph receptor and ephrin ligand-mediated interactions during angiogenesis and tumor progression

21 January 2018

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Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling

21 January 2018

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Cell-cell signaling via Eph receptors and ephrins

21 January 2018

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A novel putative tyrosine kinase receptor encoded by the eph gene

21 January 2018

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PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor

21 January 2018

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Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands

21 January 2018

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RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs

21 January 2018

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Heparan sulfate regulates ephrin-A3/EphA receptor signaling

21 January 2018

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Bidirectional signaling through ephrinA2-EphA2 enhances osteoclastogenesis and suppresses osteoblastogenesis

21 January 2018

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In human leukemia cells ephrin-B-induced invasive activity is supported by Lck and is associated with reassembling of lipid raft signaling complexes

21 January 2018

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Erythropoietin-producing hepatocyte B6 variant-derived peptides with the ability to induce glioma-reactive cytotoxic T lymphocytes in human leukocyte antigen-A2+ glioma patients

21 January 2018

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21 January 2018

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Functional analysis of H-Ryk, an atypical member of the receptor tyrosine kinase family

21 January 2018

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EphB receptors couple dendritic filopodia motility to synapse formation

21 January 2018

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Bidirectional modulation of synaptic functions by Eph/ephrin signaling.

21 January 2018

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EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets

21 January 2018

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Regulation of angiogenesis by Eph-ephrin interactions

21 January 2018

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Mechanisms and functions of Eph and ephrin signalling

21 January 2018

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Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression

21 January 2018

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Synapse development and plasticity: roles of ephrin/Eph receptor signaling

21 January 2018

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EphB receptor signaling in mouse spinal cord contributes to physical dependence on morphine

21 January 2018

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EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers

21 January 2018

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EphB6-null mutation results in compromised T cell function

21 January 2018

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Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb.

21 January 2018

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Eph and ephrin interactions in bone.

21 January 2018

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Expression of a kinase-defective Eph-like receptor in the normal human brain

21 January 2018

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Biphasic functions of the kinase-defective Ephb6 receptor in cell adhesion and migration

21 January 2018

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Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway

21 January 2018

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Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer

21 January 2018

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Organizing the thymus gland.

21 January 2018

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Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6

21 January 2018

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'Eph'ective signaling: forward, reverse and crosstalk

21 January 2018

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Gene expression signatures and biomarkers of noninvasive and invasive breast cancer cells: comprehensive profiles by representational difference analysis, microarrays and proteomics

21 January 2018

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The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells

21 January 2018

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EphB2/R-Ras signaling regulates glioma cell adhesion, growth, and invasion

21 January 2018

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Molecular cloning of two novel transmembrane ligands for Eph-related kinases (LERKS) that are related to LERK-2.

21 January 2018

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Eph receptor-ephrin bidirectional signals that target Ras and Rho proteins

21 January 2018

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Ephrin-independent regulation of cell substrate adhesion by the EphB4 receptor

21 January 2018

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EphA2 reexpression prompts invasion of melanoma cells shifting from mesenchymal to amoeboid-like motility style

21 January 2018

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Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2.

21 January 2018

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Eph-ephrin promiscuity is now crystal clear

21 January 2018

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Eph receptor signalling casts a wide net on cell behaviour

21 January 2018

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Eph-ephrin bidirectional signaling in physiology and disease

21 January 2018

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Eph receptors and ephrins in cancer: bidirectional signalling and beyond

21 January 2018

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Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes.

21 January 2018

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The ephrinB2/EphB4 axis is dysregulated in osteoprogenitors from myeloma patients and its activation affects myeloma bone disease and tumor growth

21 January 2018

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Specificity and sufficiency of EphB1 in driving the ipsilateral retinal projection

21 January 2018

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Emerging roles of the Angiopoietin-Tie and the ephrin-Eph systems as regulators of cell trafficking.

21 January 2018

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Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred

21 January 2018

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Inhibition of tumor growth and metastasis in vitro and in vivo by targeting macrophage migration inhibitory factor in human neuroblastoma.

21 January 2018

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The EphA4 receptor regulates neuronal morphology through SPAR-mediated inactivation of Rap GTPases

21 January 2018

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Platelet receptors and signaling in the dynamics of thrombus formation.

21 January 2018

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The protein tyrosine kinase family of the human genome

21 January 2018

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Learning and memory impairment in Eph receptor A6 knockout mice.

21 January 2018

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Expression of EphA2 and VEGF in squamous cell carcinoma of the tongue: correlation with the angiogenesis and clinical outcome.

21 January 2018

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Ephrin stimulation modulates T cell chemotaxis

21 January 2018

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Ephrin-A1 induces c-Cbl phosphorylation and EphA receptor down-regulation in T cells

21 January 2018

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EphA and ephrin-A proteins regulate integrin-mediated T lymphocyte interactions

21 January 2018

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Early changes in hippocampal Eph receptors precede the onset of memory decline in mouse models of Alzheimer's disease.

21 January 2018

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The ERBB3 receptor in cancer and cancer gene therapy

21 January 2018

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Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites

21 January 2018

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The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization

21 January 2018

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Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses

21 January 2018

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EphB2-mediated interactions are essential for proper migration of T cell progenitors during fetal thymus colonization.

21 January 2018

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The role of ephrins and Eph receptors in cancer

21 January 2018

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Kinase-dependent and -independent roles of EphA2 in the regulation of prostate cancer invasion and metastasis

21 January 2018

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Implications of EPHB6, EFNB2, and EFNB3 expressions in human neuroblastoma

21 January 2018

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Favorable neuroblastoma genes and molecular therapeutics of neuroblastoma

21 January 2018

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Oligomeric structure of the human EphB2 receptor SAM domain

21 January 2018

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EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis

21 January 2018

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Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling

21 January 2018

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PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands

21 January 2018

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The EphB6 receptor cooperates with c-Cbl to regulate the behavior of breast cancer cells

21 January 2018

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Mutations of ephrin-B1 (EFNB1), a marker of tissue boundary formation, cause craniofrontonasal syndrome

21 January 2018

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Regulation of mammary gland branching morphogenesis by EphA2 receptor tyrosine kinase

21 January 2018

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Additional EFNB1 mutations in craniofrontonasal syndrome.

21 January 2018

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Downregulation of EphA7 by hypermethylation in colorectal cancer

21 January 2018

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Differential expression of EphA7 receptor tyrosine kinase in gastric carcinoma

21 January 2018

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Increased expression of EphA7 correlates with adverse outcome in primary and recurrent glioblastoma multiforme patients

21 January 2018

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Clinical and genetic aspects of craniofrontonasal syndrome: towards resolving a genetic paradox

21 January 2018

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Mutations of the ephrin-B1 gene cause craniofrontonasal syndrome

21 January 2018

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Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

21 January 2018

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EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility

21 January 2018

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Ephrin-B1 is critical in T-cell development

21 January 2018

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The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer

21 January 2018

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Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1139/O10-145

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24 August 2017

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