Protein-protein interactions: principles, techniques, and their potential role in new drug development (Q37862224)

24 August 2017

1 reference

title

Protein-protein interactions: principles, techniques, and their potential role in new drug development (English)

1 reference

protein-protein interaction

24 August 2017

1 reference

Faizan Ahmad

2

1 reference

ORCID Public Data File 2021

author name string

Shagufta H Khan

1

1 reference

24 August 2017

Nihal Ahmad

3

1 reference

24 August 2017

Daniel C Flynn

4

1 reference

24 August 2017

Raj Kumar

5

1 reference

24 August 2017

1 June 2011

1 reference

Journal of Biomolecular Structure and Dynamics

24 August 2017

1 reference

24 August 2017

28

1 reference

24 August 2017

6

1 reference

24 August 2017

929-938

1 reference

Computational approaches for detecting protein complexes from protein interaction networks: a survey

24 August 2017

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural features of the interfaces in enzyme-inhibitor complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Community structure and role analysis in biological networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Functional implications of protein-protein interactions in icosahedral viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Functional genomics and networks: new approaches in the extraction of complex gene modules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Principles of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Homodimeric enzymes as drug targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Immunological synapse: a multi-protein signalling cellular apparatus for controlling gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

GPCR interacting proteins (GIPs) in the nervous system: Roles in physiology and pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Nuclear and mitochondrial signalling Akts in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Detecting and interfering protein interactions: towards the control of biochemical pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Disrupted transforming growth factor-beta signaling in spinal and bulbar muscular atrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Genetic interaction between Bardet-Biedl syndrome genes and implications for limb patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Errant ensembles: dysfunctional neuronal network dynamics in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Molecular modeling of human pentameric alpha(7) neuronal nicotinic acetylcholine receptor and its interaction with its agonist and competitive antagonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Role for protein-protein interaction databases in human genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Exploiting amino acid composition for predicting protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural and functional relationships of the steroid hormone receptors' N-terminal transactivation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Natively unfolded proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Conformational and oligomeric effects on the cysteine pK(a) of tryparedoxin peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural basis for recruitment of CBP/p300 coactivators by STAT1 and STAT2 transactivation domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Linking folding and binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Mechanism of coupled folding and binding of an intrinsically disordered protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The protein kingdom extended: ordered and intrinsically disordered proteins, their folding, supramolecular complex formation, and aggregation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Assessing protein disorder and induced folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Coupled folding and binding with alpha-helix-forming molecular recognition elements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Rational drug design via intrinsically disordered protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

TATA box binding protein induces structure in the recombinant glucocorticoid receptor AF1 domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Induced alpha-helix structure in AF1 of the androgen receptor upon binding transcription factor TFIIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Role of intrinsically disordered protein regions/domains in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Functional characterization of the native NH2-terminal transactivation domain of the human androgen receptor: binding kinetics for interactions with TFIIF and SRC-1a

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Molecular modeling studies of the interaction between Plasmodium falciparum HslU and HslV subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Dynamic interactions of proteins in complex networks: a more structured view.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The role of dynamic conformational ensembles in biomolecular recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Effect of cofactor binding and loop conformation on side chain methyl dynamics in dihydrofolate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Stability of dimeric interface in banana lectin: Insight from molecular dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A robust approach for analyzing a heterogeneous structural ensemble

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Molecular dynamics simulations to investigate the aggregation behaviors of the Abeta(17-42) oligomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural properties of the promiscuous VP16 activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Solvation energetics and conformational change in EF-hand proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Theory of multivalent binding in one and two-dimensional lattices.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Thermal unfolding of tetrameric melittin: comparison with the molten globule state of cytochrome c

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Investigating homology between proteins using energetic profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Protein dynamism and evolvability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Protein folding intermediates: native-state hydrogen exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Database of homology-derived protein structures and the structural meaning of sequence alignment

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The discovery of zinc fingers and their applications in gene regulation and genome manipulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

21 January 2018

Transcription dynamics

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The expanding universe of p53 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

STAT3 as a central regulator of tumor metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Site-specific phosphorylation induces functionally active conformation in the intrinsically disordered N-terminal activation function (AF1) domain of the glucocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A progesterone receptor co-activator (JDP2) mediates activity through interaction with residues in the carboxyl-terminal extension of the DNA binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Intrinsic structural disorder of the C-terminal activation domain from the bZIP transcription factor Fos

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Signal transduction via unstructured protein conduits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Intrinsically Disordered Proteins in Human Diseases: Introducing the D 2 Concept

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Natively disordered proteins: functions and predictions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

N-terminal domains of DELLA proteins are intrinsically unstructured in the absence of interaction with GID1/gibberellic acid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Interaction between intrinsically disordered proteins frequently occurs in a human protein-protein interaction network

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Fluorescence-quenching and resonance energy transfer studies of lipid microdomains in model and biological membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Activation of rac and cdc42 video imaged by fluorescent resonance energy transfer-based single-molecule probes in the membrane of living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Determination of hierarchical relationship of Src and Rac at subcellular locations with FRET biosensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

21 January 2018

FRET and mechanobiology

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A survey of the year 2007 literature on applications of isothermal titration calorimetry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Direct measurement of protein binding energetics by isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Rapid measurement of binding constants and heats of binding using a new titration calorimeter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A survey of the year 2006 literature on applications of isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Evaluation of linked protonation effects in protein binding reactions using isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Thermodynamics of protein-peptide interactions in the ribonuclease S system studied by titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Survey of the year 2004: literature on applications of isothermal titration calorimetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

ITC in the post-genomic era...? Priceless

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Isothermal titration calorimetry: experimental design, data analysis, and probing macromolecule/ligand binding and kinetic interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Analysis of biomolecules using surface plasmons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Molecular interactions in the insulin-like growth factor (IGF) axis: a surface plasmon resonance (SPR) based biosensor study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Methods for the detection and analysis of protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A unified view of propagating and localized surface plasmon resonance biosensors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Search for antiamyloidogenic compounds based on a nucleation-dependent polymerization model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Exploring the complement interaction network using surface plasmon resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Yeast two-hybrid, a powerful tool for systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Protein-protein interactions: from global to local analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The nature of systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Physiological and functional interactions between Tcf4 and Daxx in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Identification of a co-repressor that inhibits the transcriptional and growth-arrest activities of CCAAT/enhancer-binding protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Rac3-induced neuritogenesis requires binding to Neurabin I

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Interactions between PIAS proteins and SOX9 result in an increase in the cellular concentrations of SOX9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Functional analysis of the triplex proteins (VP19C and VP23) of herpes simplex virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A novel genetic system to detect protein-protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Identification of SUMO-interacting proteins by yeast two-hybrid analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Two-hybrid technologies in proteomics research

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Chemical probes for histone-modifying enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Differential roles of p300 and PCAF acetyltransferases in muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Small molecule modulators of histone acetyltransferase p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Functional analysis of p53 binding under differential stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Regulation of murine TGFbeta2 by Pax3 during early embryonic development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Characterization of distant enhancers and promoters in the albumin-alpha-fetoprotein locus during active and silenced expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

The current state of chromatin immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Analysis of protein-DNA interactions during meiosis by quantitative chromatin immunoprecipitation (qChIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Methods for proteomic analysis of transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structural and mechanistic determinants of affinity and specificity of ligands discovered or engineered by phage display

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Display technologies expand their horizons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Protein networks in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Chemical genomics: probing protein function using small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Structure-based and ligand-based drug design for HER 2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Interactions between PrP(c) and other ligands with the 37-kDa/67-kDa laminin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Protein binding hot spots and the residue-residue pairing preference: a water exclusion perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Investigation of the effect of glycosylation on human prion protein by molecular dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

Molecular basis of cytokine signalling--theme and variations

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

BIOCHEMISTRY: How Do Proteins Interact?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F07391102.2011.10508619

10.1080/07391102.2011.10508619

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference