Alzheimer's pathogenesis: is there neuron-to-neuron propagation? (Q37868480)

24 August 2017

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title

Alzheimer's pathogenesis: is there neuron-to-neuron propagation? (English)

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24 August 2017

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Heiko Braak

1

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PubMed ID

21516512

24 August 2017

Kelly Del Tredici

series ordinal

2

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24 August 2017

24 April 2011

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24 August 2017

Acta Neuropathologica

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24 August 2017

121

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24 August 2017

589-595

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24 August 2017

5

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https://scigraph.springernature.com/pub.10.1007/s00401-011-0825-z

24 August 2017

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cites work

The transcellular spread of cytosolic amyloids, prions, and prionoids

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Mechanism of tau-induced neurodegeneration in Alzheimer disease and related tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Prodromal Alzheimer's disease: successive emergence of the clinical symptoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Are synucleinopathies prion-like disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The Topographical and Neuroanatomical Distribution of Neurofibrillary Tangles and Neuritic Plaques in the Cerebral Cortex of Patients with Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Tau-mediated neurodegeneration in Alzheimer's disease and related disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The locus ceruleus norepinephrine system: functional organization and potential clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Duration of neurofibrillary changes in the hippocampal pyramidal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neuropathological stageing of Alzheimer-related changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Frequency of stages of Alzheimer-related lesions in different age categories

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Alzheimer's disease: intraneuronal alterations precede insoluble amyloid-beta formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Prion-like transmission of protein aggregates in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Transmission and spreading of tauopathy in transgenic mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Recovery recapitulates ontogeny

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Membrane nanotubes: dynamic long-distance connections between animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The role of cortical connectivity in Alzheimer's disease pathogenesis: a review and model system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Prediction of pathology in primary progressive language and speech disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Prevalence, incidence and duration of Braak's stages in the general population: can we know?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Why pleiotropic interventions are needed for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The expanding realm of prion phenomena in neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Propagation of tau misfolding from the outside to the inside of a cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Conformational diversity of wild-type Tau fibrils specified by templated conformation change

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Disease-specific patterns of locus coeruleus cell loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Monoclonal antibody AT8 recognises tau protein phosphorylated at both serine 202 and threonine 205.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The propagation of prion-like protein inclusions in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Tunnelling nanotubes: a highway for prion spreading?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The dorsal raphe nucleus shows phospho-tau neurofibrillary changes before the transentorhinal region in Alzheimer's disease. A precocious onset?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Locus ceruleus degeneration is ubiquitous in Alzheimer's disease: possible implications for diagnosis and treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

New neuropathological criteria for Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Mechanisms of tau-induced neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The evolution and pathology of frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Transition of tau protein from disordered to misordered in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Disruption of microtubule network by Alzheimer abnormally hyperphosphorylated tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neuron loss in key cholinergic and aminergic nuclei in Alzheimer disease: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Structural principles of tau and the paired helical filaments of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Converging molecular pathways in human neural development and degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

From sensation to cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Early-life risk factors and the development of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neurons may live for decades with neurofibrillary tangles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Molecular neuropathology of TDP-43 proteinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Is Parkinson's disease a prion disorder?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The selective vulnerability of brainstem nuclei to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Cortical connections and the pathology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Reassessing the amyloid cascade hypothesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Laminar origins and terminations of cortical connections of the occipital lobe in the rhesus monkey

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

The locus coeruleus and noradrenergic modulation of cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Spatial and temporal relationships between plaques and tangles in Alzheimer-pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Alzheimer's disease: a central role for amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Does Alzheimer's disease begin in the brainstem?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Exosomes--vesicular carriers for intercellular communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Tau pathophysiology in neurodegeneration: a tangled issue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neuroplasticity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Phases of A beta-deposition in the human brain and its relevance for the development of AD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Multivesicular bodies in neurons: distribution, protein content, and trafficking functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide--the first step of a fatal cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-011-0825-Z

10.1007/S00401-011-0825-Z

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21516512