The complex world of oligodendroglial differentiation inhibitors (Q37869047)

24 August 2017

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title

The complex world of oligodendroglial differentiation inhibitors (English)

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24 August 2017

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3

Hans-Peter Hartung

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24 August 2017

David Kremer

1

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PubMed ID

21520230

24 August 2017

Orhan Aktas

series ordinal

2

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PubMed ID

21520230

24 August 2017

Patrick Küry

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4

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24 August 2017

1 April 2011

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24 August 2017

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24 August 2017

69

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24 August 2017

4

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24 August 2017

602-618

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The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration

24 August 2017

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Premyelinating oligodendrocytes in chronic lesions of multiple sclerosis

21 January 2018

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Mechanisms of CNS remyelination--the key to therapeutic advances.

21 January 2018

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Origin of oligodendrocytes in the subventricular zone of the adult brain.

21 January 2018

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Activation of the subventricular zone in multiple sclerosis: evidence for early glial progenitors.

21 January 2018

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Experimental autoimmune encephalomyelitis mobilizes neural progenitors from the subventricular zone to undergo oligodendrogenesis in adult mice

21 January 2018

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Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis.

21 January 2018

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Two-tier transcriptional control of oligodendrocyte differentiation

21 January 2018

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Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation

21 January 2018

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Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination.

21 January 2018

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Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination.

21 January 2018

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Oligodendrocyte precursor cells from different brain regions express divergent properties consistent with the differing time courses of myelination in these regions

21 January 2018

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Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

21 January 2018

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Notch receptor activation inhibits oligodendrocyte differentiation

21 January 2018

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Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals

21 January 2018

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Wnt signaling controls the timing of oligodendrocyte development in the spinal cord.

21 January 2018

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Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

21 January 2018

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HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

21 January 2018

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Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

21 January 2018

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Re-expression of PSA-NCAM by demyelinated axons: an inhibitor of remyelination in multiple sclerosis?

21 January 2018

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Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule

21 January 2018

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Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

21 January 2018

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Rho and Rac take center stage

21 January 2018

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LINGO-1 negatively regulates myelination by oligodendrocytes

21 January 2018

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Developmental analysis of Lingo-1/Lern1 protein expression in the mouse brain: interaction of its intracellular domain with Myt1l

21 January 2018

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Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

21 January 2018

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TROY and LINGO-1 expression in astrocytes and macrophages/microglia in multiple sclerosis lesions.

21 January 2018

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TAJ/TROY, an orphan TNF receptor family member, binds Nogo-66 receptor 1 and regulates axonal regeneration

21 January 2018

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The Id4 HLH protein and the timing of oligodendrocyte differentiation

21 January 2018

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Multiple roles of Id4 in developmental myelination: predicted outcomes and unexpected findings

21 January 2018

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CDK inhibitors: cell cycle regulators and beyond

21 January 2018

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The cyclin-dependent kinase inhibitor p57kip2 is a negative regulator of Schwann cell differentiation and in vitro myelination.

21 January 2018

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p57kip2 is dynamically regulated in experimental autoimmune encephalomyelitis and interferes with oligodendroglial maturation

21 January 2018

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p57 kip2's role beyond Schwann cell cycle control

21 January 2018

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Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase

21 January 2018

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Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination

21 January 2018

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Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits

21 January 2018

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The oligodendrocyte-specific G protein-coupled receptor GPR17 is a cell-intrinsic timer of myelination

21 January 2018

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Paracrine control of oligodendrocyte differentiation by SRF-directed neuronal gene expression.

21 January 2018

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Interferon-gamma protects against cuprizone-induced demyelination.

21 January 2018

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Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress.

21 January 2018

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Interferon-gamma inhibits cell cycle exit in differentiating oligodendrocyte progenitor cells

21 January 2018

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Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells

21 January 2018

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Contact with central nervous system myelin inhibits oligodendrocyte progenitor maturation.

21 January 2018

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Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation

21 January 2018

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Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

21 January 2018

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Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5

21 January 2018

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Disorder-associated mutations lead to functional inactivation of neuroligins

21 January 2018

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Altered MAP kinase phosphorylation and impaired motor coordination in PTPRR deficient mice

21 January 2018

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Distribution of TRPC4 in developing and adult murine brain.

21 January 2018

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Site-selective dephosphorylation of the platelet-derived growth factor beta-receptor by the receptor-like protein-tyrosine phosphatase DEP-1

21 January 2018

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The ErbB4 neuregulin receptor mediates suppression of oligodendrocyte maturation.

21 January 2018

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Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

21 January 2018

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Metabotropic P2 receptor activation regulates oligodendrocyte progenitor migration and development.

21 January 2018

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Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials

21 January 2018

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Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development

21 January 2018

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Insulin-like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro.

21 January 2018

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Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice.

21 January 2018

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Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

21 January 2018

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Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

21 January 2018

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Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation

21 January 2018

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Stimulation of the myelin basic protein gene expression by 9-cis-retinoic acid and thyroid hormone: activation in the context of its native promoter

21 January 2018

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Expression of thyroid hormone receptor isoforms in the oligodendrocyte lineage.

21 January 2018

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Type 3 deiodinase expression in inflammatory spinal cord lesions in rat experimental autoimmune encephalomyelitis

21 January 2018

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Signaling via immunoglobulin Fc receptors induces oligodendrocyte precursor cell differentiation

21 January 2018

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Laminin alters fyn regulatory mechanisms and promotes oligodendrocyte development

21 January 2018

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Protein-tyrosine phosphatase alpha acts as an upstream regulator of Fyn signaling to promote oligodendrocyte differentiation and myelination

21 January 2018

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Alterations in the oligodendrocyte lineage, myelin, and white matter in adult mice lacking the chemokine receptor CXCR2.

21 January 2018

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Modulation of rat oligodendrocyte precursor cells by the chemokine CXCL12.

21 January 2018

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Activation of CXCR7 receptor promotes oligodendroglial cell maturation.

21 January 2018

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CXCR4 promotes differentiation of oligodendrocyte progenitors and remyelination

21 January 2018

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Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination

21 January 2018

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Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin

21 January 2018

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Type III neuregulin-1 promotes oligodendrocyte myelination

21 January 2018

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Antioxidants and polyunsaturated fatty acids in multiple sclerosis

21 January 2018

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Retinoid X receptor gamma signaling accelerates CNS remyelination

21 January 2018

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Clinically validated approaches to the treatment of autoimmune diseases

21 January 2018

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Anti-chemokine small molecule drugs: a promising future?

21 January 2018

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Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis

21 January 2018

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Distinct stages of myelination regulated by gamma-secretase and astrocytes in a rapidly myelinating CNS coculture system

21 January 2018

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Notch Signaling and ERK Activation Are Important for the Osteomimetic Properties of Prostate Cancer Bone Metastatic Cell Lines

21 January 2018

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A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma

21 January 2018

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Metastasis suppressor CC3 inhibits angiogenic properties of tumor cells in vitro

21 January 2018

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Alternatively spliced products CC3 and TC3 have opposing effects on apoptosis

21 January 2018

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Fetuin/alpha2-HS glycoprotein is a transforming growth factor-beta type II receptor mimic and cytokine antagonist

21 January 2018

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The inhibitory effects of transforming growth factor-beta-1 (TGF-beta1) in autoimmune diseases

21 January 2018

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Protein kinase C-activating tumor promoters enhance the differentiation of astrocytes in aggregating fetal brain cell cultures.

21 January 2018

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Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation

21 January 2018

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p190RhoGAP can act to inhibit PDGF-induced gliomas in mice: a putative tumor suppressor encoded on human chromosome 19q13.3.

21 January 2018

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RhoA/ROCK signaling is critical to FAK activation by cyclic stretch in cardiac myocytes.

21 January 2018

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RhoA and ROCK promote migration by limiting membrane protrusions

21 January 2018

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Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development

21 January 2018

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Xenopus Cdc42 regulates convergent extension movements during gastrulation through Wnt/Ca2+ signaling pathway

21 January 2018

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The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

21 January 2018

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Dapper 1 antagonizes Wnt signaling by promoting dishevelled degradation

21 January 2018

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Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN-mutated prostate cancer cells

21 January 2018

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Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers.

21 January 2018

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The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals

21 January 2018

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Quercetin, a potent inhibitor against beta-catenin/Tcf signaling in SW480 colon cancer cells.

21 January 2018

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Epigenetic regulation of Wnt-signaling pathway in acute lymphoblastic leukemia

21 January 2018

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Transvascular delivery of small interfering RNA to the central nervous system.

21 January 2018

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Therapeutic potential of small interfering RNA for central nervous system diseases

21 January 2018

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RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia.

21 January 2018

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Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference.

21 January 2018

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Targeting Alzheimer's disease genes with RNA interference: an efficient strategy for silencing mutant alleles

21 January 2018

1 reference

Downregulation of uPA, uPAR and MMP-9 using small, interfering, hairpin RNA (siRNA) inhibits glioma cell invasion, angiogenesis and tumor growth

21 January 2018

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Silencing Nogo-A promotes functional recovery in demyelinating disease

21 January 2018

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Lentivirus-mediated transgene delivery to the hippocampus reveals sub-field specific differences in expression.

21 January 2018

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Multiple sclerosis: oligodendrocytes display cell death-related molecules in situ but do not undergo apoptosis.

21 January 2018

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TNF-induced death of adult human oligodendrocytes is mediated by c-jun NH2-terminal kinase-3.

21 January 2018

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Novel cross-talk between three cardiovascular regulators: thrombin cleavage fragment of Jagged1 induces fibroblast growth factor 1 expression and release

21 January 2018

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Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.

21 January 2018

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Rational design and synthesis of potent dibenzazepine motifs as beta-secretase inhibitors

21 January 2018

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Blocking TLR2 in vivo protects against accumulation of inflammatory cells and neuronal injury in experimental stroke

21 January 2018

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Development of a cell transducible RhoA inhibitor TAT-C3 transferase and its encapsulation in biocompatible microspheres to promote survival and enhance regeneration of severed neurons

21 January 2018

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Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARgamma-independent pathway in human aortic smooth muscle cells

21 January 2018

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The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

21 January 2018

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The C-terminal peptide of connective tissue growth factor blocks the full molecule binding to tubular epithelial cell

21 January 2018

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Structure and mechanism of IFN- antagonism by an orthopoxvirus IFN- -binding protein

21 January 2018

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Chemokine antagonists that discriminate between interleukin-8 receptors. Selective blockers of CXCR2.

21 January 2018

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CXCR2 blockade impairs angiotensin II-induced CC chemokine synthesis and mononuclear leukocyte infiltration

21 January 2018

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SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor

21 January 2018

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Rho kinase inhibitors Y27632 and H1152 augment neurite extension in the presence of cultured Schwann cells

21 January 2018

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Hyposmolarity-induced ErbB4 phosphorylation and its influence on the non-receptor tyrosine kinase network response in cultured cerebellar granule neurons

21 January 2018

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Extracellular BMP-antagonist regulation in development and disease: tied up in knots

21 January 2018

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Isoform-specific inhibition of TRPC4 channel by phosphatidylinositol 4,5-bisphosphate

21 January 2018

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LINGO-1 antagonist promotes spinal cord remyelination and axonal integrity in MOG-induced experimental autoimmune encephalomyelitis

21 January 2018

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Calphostins (UCN-1028), novel and specific inhibitors of protein kinase C. I. Fermentation, isolation, physico-chemical properties and biological activities

21 January 2018

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.42.1470

Identifiers

DOI

10.1002/ANA.22415

1 reference

24 August 2017

1 reference

PubMed ID

21520230