Alternative affinity tools: more attractive than antibodies? (Q37869534)

24 August 2017

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title

Alternative affinity tools: more attractive than antibodies? (English)

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24 August 2017

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5

John van der Oost

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Mark Levisson

object named as

Mark Levisson

2

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Hauke Smidt

object named as

Hauke Smidt

4

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author name string

Vincent J B Ruigrok

1

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24 August 2017

Michel H M Eppink

3

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24 August 2017

language of work or name

English

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publication date

1 May 2011

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24 August 2017

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24 August 2017

volume

436

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24 August 2017

issue

1

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24 August 2017

page(s)

1-13

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Selecting and screening recombinant antibody libraries

24 August 2017

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An alternative strategy for high throughput generation and characterization of monoclonal antibodies against human plasma proteins using fractionated native proteins as immunogens

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Selection methods for high-producing mammalian cell lines.

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Proteomics and diagnostics: Let's Get Specific, again

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Point-of-care immunotesting: approaching the analytical performance of central laboratory methods

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Immunotherapy: past, present and future

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Strategies and challenges for the next generation of therapeutic antibodies

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Fully human antibodies from transgenic mouse and phage display platforms

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Getting specific: monoclonal antibodies in multiple sclerosis.

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Arming antibodies: prospects and challenges for immunoconjugates

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Potent antibody therapeutics by design

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Engineered antibody fragments and the rise of single domains

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Naturally occurring antibodies devoid of light chains

21 January 2018

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Crystal structure of a shark single-domain antibody V region in complex with lysozyme

21 January 2018

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Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

21 January 2018

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Properties, production, and applications of camelid single-domain antibody fragments

21 January 2018

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Monitoring biodegradative enzymes with nanobodies raised in Camelus dromedarius with mixtures of catabolic proteins

21 January 2018

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Phage display for engineering and analyzing protein interaction interfaces

21 January 2018

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Protein engineering with bacterial display

21 January 2018

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Yeast surface display for protein engineering and characterization

21 January 2018

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Ribosome display: selecting and evolving proteins in vitro that specifically bind to a target

21 January 2018

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In-vitro protein evolution by ribosome display and mRNA display

21 January 2018

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Phage display systems and their applications

21 January 2018

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Engineering M13 for phage display

21 January 2018

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Filamentous phage display in the new millennium

21 January 2018

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Phage display: concept, innovations, applications and future

21 January 2018

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Progress in phage display: evolution of the technique and its application

21 January 2018

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Binding proteins from alternative scaffolds

21 January 2018

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Artificial, non-antibody binding proteins for pharmaceutical and industrial applications

21 January 2018

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Biopharmaceutical drug discovery using novel protein scaffolds

21 January 2018

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A new generation of protein display scaffolds for molecular recognition

21 January 2018

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Alternative non-antibody scaffolds for molecular recognition

21 January 2018

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Engineered affinity proteins--generation and applications

21 January 2018

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Display scaffolds: protein engineering for novel therapeutics

21 January 2018

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FN3: a new protein scaffold reaches the clinic

21 January 2018

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The fibronectin type III domain as a scaffold for novel binding proteins

21 January 2018

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Directed evolution of high-affinity antibody mimics using mRNA display

21 January 2018

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DARPins: a new generation of protein therapeutics.

21 January 2018

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High-affinity binders selected from designed ankyrin repeat protein libraries

21 January 2018

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Designed ankyrin repeat proteins as anti-idiotypic-binding molecules

21 January 2018

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Hyperthermophilic enzymes--stability, activity and implementation strategies for high temperature applications.

21 January 2018

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ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome

21 January 2018

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In vitro selection of DNA aptamers binding ethanolamine

21 January 2018

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Development of DNA aptamers for cytochemical detection of acetylcholine

21 January 2018

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Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase

21 January 2018

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Selection of single-stranded DNA molecules that bind and inhibit human thrombin

21 January 2018

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Combining use of a panel of ssDNA aptamers in the detection of Staphylococcus aureus

21 January 2018

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Selection of aptamers for molecular recognition and characterization of cancer cells

21 January 2018

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High-resolution molecular discrimination by RNA.

21 January 2018

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In vitro selection of RNA molecules that bind specific ligands

21 January 2018

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FluMag-SELEX as an advantageous method for DNA aptamer selection

21 January 2018

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SELEX--a (r)evolutionary method to generate high-affinity nucleic acid ligands

21 January 2018

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In vitro selection of structure-switching, self-reporting aptamers

21 January 2018

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In vitro selection of DNA aptamers which bind to cholic acid.

21 January 2018

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Conservative secondary structure motif of streptavidin-binding aptamers generated by different laboratories.

21 January 2018

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An enzyme-linked oligonucleotide assay

21 January 2018

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Molecular beacons: probes that fluoresce upon hybridization

21 January 2018

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Molecular beacons with intrinsically fluorescent nucleotides

21 January 2018

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An electronic, aptamer-based small-molecule sensor for the rapid, label-free detection of cocaine in adulterated samples and biological fluids

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101860

Target-responsive structural switching for nucleic acid-based sensors

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101860

Selection of aptamers for a protein target in cell lysate and their application to protein purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Covalently bonded DNA aptamer chiral stationary phase for the chromatographic resolution of adenosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Pegaptanib for neovascular age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamers as therapeutics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Liposome-anchored vascular endothelial growth factor aptamers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamer-based multiplexed proteomic technology for biomarker discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamers: molecular tools for analytical applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Determination of ochratoxin a with a DNA aptamer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamers as inhibitors of target proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Oligo oligarchy-the surprisingly small world of aptamers

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101860

The chemical biology of aptamers

21 January 2018

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https://api.crossref.org/works/10.1042%2FBJ20101860

SELEX with modified nucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Mirror-image RNA that binds D-adenosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Expanding the chemistry of DNA for in vitro selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

The Preparation of Specific Adsorbents

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Synthetic strategies for the generation of molecularly imprinted organic polymers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Optimization, evaluation, and characterization of molecularly imprinted polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Too large to fit? Recent developments in macromolecular imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Template-imprinted nanostructured surfaces for protein recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Molecular imprinting of proteins emerging as a tool for protein recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

How to find effective functional monomers for effective molecularly imprinted polymers?

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Combinatorial methods in molecular imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Molecularly imprinted sorbent assays: recent developments and applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Molecularly imprinted polymers for sample preparation: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Optimization of the class-selective extraction of triazines from aqueous samples using a molecularly imprinted polymer by a comprehensive approach of the retention mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Drug assay using antibody mimics made by molecular imprinting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Molecularly templated materials in chemical sensing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Molecularly imprinted polymers in the drug discovery process

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Synthesis and screening of a molecularly imprinted polymer library targeted for penicillin G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Chemical synthesis in nanosized cavities

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Recognition, neutralization, and clearance of target peptides in the bloodstream of living mice by molecularly imprinted polymer nanoparticles: a plastic antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Production and characterization of a genetically engineered anti-caffeine camelid antibody and its use in immunoaffinity chromatography.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamers as analytical reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Single-step purification of recombinant Thermus aquaticus DNA polymerase using DNA-aptamer immobilized novel affinity magnetic beads

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Protein A chromatography for antibody purification

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

Aptamer-based biosensor arrays for detection and quantification of biological macromolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

A potent and highly specific FN3 monobody inhibitor of the Abl SH2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

In vitro evolution of a self-alkylatlng ribozyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20101860

21 January 2018

Identifiers

DOI

10.1042/BJ20101860

1 reference

24 August 2017

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