Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease (Q37880104)

24 August 2017

1 reference

title

Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease (English)

1 reference

24 August 2017

1 reference

Nilanjan Ghosh

1

1 reference

PubMed ID

21615270

24 August 2017

Rituparna Ghosh

series ordinal

2

1 reference

PubMed ID

21615270

24 August 2017

Subhash C Mandal

series ordinal

3

1 reference

24 August 2017

26 May 2011

1 reference

24 August 2017

Free Radical Research

1 reference

24 August 2017

45

1 reference

24 August 2017

8

1 reference

24 August 2017

888-905

1 reference

Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death

24 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Superoxide dismutase activity in Alzheimer's disease: possible mechanism for paired helical filament formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Parkinson's disease: a disorder due to nigral glutathione deficiency?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Alterations in the distribution of glutathione in the substantia nigra in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Oxidative damage to mitochondrial DNA in spinal motoneurons of transgenic ALS mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Early decrease of redox factor-1 in spinal motor neurons of presymptomatic transgenic mice with a mutant SOD1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Increased oxidative stress and astrogliosis responses in conditional double-knockout mice of Alzheimer-like presenilin-1 and presenilin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Vesicle permeabilization by protofibrillar alpha-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Monomeric Cu,Zn-superoxide dismutase is a common misfolding intermediate in the oxidation models of sporadic and familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Dopamine toxicity in neuroblastoma cells: role of glutathione depletion by L-BSO and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Physiological significance of reactive cysteine residues of Keap1 in determining Nrf2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Cysteine-based regulation of the CUL3 adaptor protein Keap1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The Nrf2 system as a potential target for the development of indirect antioxidants.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Regulation of genes encoding NAD(P)H:quinone oxidoreductases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Contribution of NAD(P)H:quinone oxidoreductase 1 to protection against carcinogenesis, and regulation of its gene by the Nrf2 basic-region leucine zipper and the arylhydrocarbon receptor basic helix-loop-helix transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Upregulation of NF-E2-related factor-2-dependent glutathione by carnosol provokes a cytoprotective response and enhances cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Redox homeostasis modulates the sensitivity of myeloma cells to bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Glutathione pathways in the brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

21 January 2018

Glutathione transferases

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Pharmacological and clinical aspects of heme oxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Gene regulation of heme oxygenase-1 as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Redox regulation of heat shock protein expression by signaling involving nitric oxide and carbon monoxide: relevance to brain aging, neurodegenerative disorders, and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Heme oxygenase-1 and neurodegeneration: expanding frontiers of engagement

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Heat shock proteins and protection of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The neuroprotective potential of heat shock protein 70 (HSP70).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: influence of Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Overexpression of HSP72 after induction of experimental stroke protects neurons from ischemic damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

HSP27 and cell survival in neurones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Neuroprotective effect of small heat shock protein, Hsp27, after acute and chronic alcohol administration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Increased synthesis and accumulation of heat shock 70 proteins in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Transduced HSP27 protein protects neuronal cell death by enhancing FALS-associated SOD1 mutant activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Hsp27 and Hsp70 administered in combination have a potent protective effect against FALS-associated SOD1-mutant-induced cell death in mammalian neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Thioredoxin: a key regulator of cardiovascular homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Modulation of glutathione and thioredoxin systems by calorie restriction during the aging process

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Physiological functions of thioredoxin and thioredoxin reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Redox control of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Thioredoxin as a neurotrophic cofactor and an important regulator of neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Protective effects on neuronal cells of mouse afforded by ebselen against oxidative stress at multiple steps

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Protective effects of S-nitrosoglutathione against amyloid beta-peptide neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

A therapeutic role for sirtuins in diseases of aging?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Interaction of aging-associated signaling cascades: inhibition of NF-kappaB signaling by longevity factors FoxOs and SIRT1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Sirtuins: the 'magnificent seven', function, metabolism and longevity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Dynamics of the action of dFOXO on adult mortality in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The sirtuin pathway in ageing and Alzheimer disease: mechanistic and therapeutic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Enhanced tolerance against early and late apoptotic oxidative stress in mammalian neurons through nicotinamidase and sirtuin mediated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Resveratrol protects against experimental stroke: putative neuroprotective role of heme oxygenase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Heme oxygenase 1: another possible target to explain the neuroprotective action of resveratrol, a multifaceted nutrient-based molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Protective effects of resveratrol and quercetin against MPP+ -induced oxidative stress act by modulating markers of apoptotic death in dopaminergic neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Catalysis and mechanistic insights into sirtuin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Enhanced glutathione efflux from astrocytes in culture by low extracellular Ca2+ and curcumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Glutamoyl diester of the dietary polyphenol curcumin offers improved protection against peroxynitrite-mediated nitrosative stress and damage of brain mitochondria in vitro: implications for Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Curcumin treatment enhances islet recovery by induction of heat shock response proteins, Hsp70 and heme oxygenase-1, during cryopreservation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Curcumin protects rat myocardium against isoproterenol-induced ischemic injury: attenuation of ventricular dysfunction through increased expression of Hsp27 along with strengthening antioxidant defense system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Protective effect of supercritical fluid rosemary extract, Rosmarinus officinalis, on antioxidants of major organs of aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Beneficial effects of carnosic acid on dieldrin-induced dopaminergic neuronal cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Sulforaphane protects brains against hypoxic-ischemic injury through induction of Nrf2-dependent phase 2 enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Sulforaphane protects cortical neurons against 5-S-cysteinyl-dopamine-induced toxicity through the activation of ERK1/2, Nrf-2 and the upregulation of detoxification enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Sulforaphane as an inducer of glutathione prevents oxidative stress-induced cell death in a dopaminergic-like neuroblastoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Induction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The neuroprotective potential of phase II enzyme inducer on motor neuron survival in traumatic spinal cord injury in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Stabilization of transcription factor Nrf2 by tBHQ prevents oxidative stress-induced amyloid beta formation in NT2N neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Nrf2-mediated protection against 6-hydroxydopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Keap1-Nrf2 activation in the presence and absence of DJ-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Neurological mechanisms of green tea polyphenols in Alzheimer's and Parkinson's diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Upregulation of heme oxygenase-1 by Epigallocatechin-3-gallate via the phosphatidylinositol 3-kinase/Akt and ERK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The major green tea polyphenol, (-)-epigallocatechin-3-gallate, induces heme oxygenase in rat neurons and acts as an effective neuroprotective agent against oxidative stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

EGCG protects HT-22 cells against glutamate-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Neuroprotective effect of epigallocatechin-3-gallate against beta-amyloid-induced oxidative and nitrosative cell death via augmentation of antioxidant defense capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Inhibitory effect of green tea extract on beta-amyloid-induced PC12 cell death by inhibition of the activation of NF-kappaB and ERK/p38 MAP kinase pathway through antioxidant mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

A pro-drug of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) prevents differentiated SH-SY5Y cells from toxicity induced by 6-hydroxydopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Mitochondrial alterations in aging rat brain: effective role of (-)-epigallo catechin gallate.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Neuroprotective effects of (-)-epigallocatechin-3-gallate in a transgenic mouse model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

The antioxidant activity of standardized extract of Ginkgo biloba (EGb 761) in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

Ginkgo biloba extract neuroprotective action is dependent on heme oxygenase 1 in ischemic reperfusion brain injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

EGb761 protects hydrogen peroxide-induced death of spinal cord neurons through inhibition of intracellular ROS production and modulation of apoptotic regulating genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

EGb761 protects against nigrostriatal dopaminergic neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice: role of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10715762.2011.574290

10.3109/10715762.2011.574290

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21615270