Cerebrospinal fluid biomarkers for Alzheimer's disease: the present and the future. (Q37895052)

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6 February 2020

review article

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title

Cerebrospinal fluid biomarkers for Alzheimer's disease: the present and the future (English)

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6 February 2020

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6 February 2020

Luisa Benussi

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6 February 2020

Anna Paterlini

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6 February 2020

Giuliano Binetti

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6 February 2020

Enzo Emanuele

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6 February 2020

4

Valentina Albertini

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6 February 2020

publication date

25 June 2011

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Neurodegenerative Diseases

6 February 2020

published in

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6 February 2020

volume

8

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6 February 2020

issue

6

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6 February 2020

page(s)

413-420

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6 February 2020

1 reference

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

21 January 2018

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Multimodal techniques for diagnosis and prognosis of Alzheimer's disease

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Mild cognitive impairment: clinical characterization and outcome

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Current concepts in mild cognitive impairment

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Revising the definition of Alzheimer's disease: a new lexicon.

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Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteria

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The new Alzheimer's criteria in a naturalistic series of patients with mild cognitive impairment.

21 January 2018

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Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

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Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: Beta-amyloid(1-42), tau, phospho-tau-181 and total protein

21 January 2018

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Cerebrospinal fluid tau, A beta, and phosphorylated tau protein for the diagnosis of Alzheimer's disease.

21 January 2018

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CSF biomarkers: pinpointing Alzheimer pathogenesis

21 January 2018

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Biological CSF markers of Alzheimer's disease

21 January 2018

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CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment.

21 January 2018

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Biomarkers for Alzheimer's disease: ready for the next step

21 January 2018

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Use of cerebrospinal fluid biomarkers for diagnosis of incipient Alzheimer disease in patients with mild cognitive impairment.

21 January 2018

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Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease

21 January 2018

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Statistical evaluation of prognostic versus diagnostic models: beyond the ROC curve

21 January 2018

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F(2)-isoprostanes as biomarkers of late-onset Alzheimer's disease.

21 January 2018

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The brain injury biomarker VLP-1 is increased in the cerebrospinal fluid of Alzheimer disease patients

21 January 2018

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Growth factors and cytokines/chemokines as surrogate biomarkers in cerebrospinal fluid and blood for diagnosing Alzheimer's disease and mild cognitive impairment

21 January 2018

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Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment

21 January 2018

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Biomarkers of inflammation and amyloid-beta phagocytosis in patients at risk of Alzheimer disease

21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Beta-amyloid precursor protein cleavage by a membrane-bound protease

21 January 2018

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Increased beta-Secretase activity in cerebrospinal fluid of Alzheimer's disease subjects.

21 January 2018

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Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment.

21 January 2018

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Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease

21 January 2018

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Elevated cerebrospinal fluid BACE1 activity in incipient Alzheimer disease

21 January 2018

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Heterogeneity of water-soluble amyloid beta-peptide in Alzheimer's disease and Down's syndrome brains.

21 January 2018

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Amyloid beta1-40 quantification in CSF: comparison between chromatographic and immunochemical methods

21 January 2018

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The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide

21 January 2018

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Determination of beta-amyloid peptide signatures in cerebrospinal fluid using immunoprecipitation-mass spectrometry

21 January 2018

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Characterization of amyloid beta peptides in cerebrospinal fluid by an automated immunoprecipitation procedure followed by mass spectrometry

21 January 2018

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Optimization protocol for amyloid-β peptides detection in human cerebrospinal fluid using SELDI TOF MS.

21 January 2018

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Distinct cerebrospinal fluid amyloid beta peptide signatures in sporadic and PSEN1 A431E-associated familial Alzheimer's disease

21 January 2018

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Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.

21 January 2018

1 reference

Cerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer's disease determined by protein biochip technology

21 January 2018

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An Alzheimer's disease-specific beta-amyloid fragment signature in cerebrospinal fluid

21 January 2018

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Amino-truncated beta-amyloid42 peptides in cerebrospinal fluid and prediction of progression of mild cognitive impairment

21 January 2018

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Predicting progression of Alzheimer's disease

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

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Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

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Amyloid beta protein dimer-containing human CSF disrupts synaptic plasticity: prevention by systemic passive immunization

21 January 2018

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A beta oligomers - a decade of discovery

21 January 2018

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Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy.

21 January 2018

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Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

21 January 2018

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Oligomerization partially explains the lowering of Abeta42 in Alzheimer's disease cerebrospinal fluid.

21 January 2018

1 reference

High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

21 January 2018

1 reference

The use of proteomics in biomarker discovery in neurodegenerative diseases

21 January 2018

1 reference

Identification of the apolipoprotein E4 isoform in cerebrospinal fluid with preparative two-dimensional electrophoresis and matrix assisted laser desorption/ionization-time of flight-mass spectrometry

21 January 2018

1 reference

Studies of potential cerebrospinal fluid molecular markers for Alzheimer's disease

21 January 2018

1 reference

Proteomic studies of potential cerebrospinal fluid protein markers for Alzheimer's disease

21 January 2018

1 reference

A panel of cerebrospinal fluid potential biomarkers for the diagnosis of Alzheimer's disease.

21 January 2018

1 reference

Multiplexed proteomic analysis of oxidation and concentrations of cerebrospinal fluid proteins in Alzheimer disease.

21 January 2018

1 reference

Structural and quantitative comparison of cerebrospinal fluid glycoproteins in Alzheimer's disease patients and healthy individuals

21 January 2018

1 reference

Clinical proteomics in neurodegenerative disorders

21 January 2018

1 reference

Identification of a novel panel of cerebrospinal fluid biomarkers for Alzheimer's disease.

21 January 2018

1 reference

S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10

21 January 2018

1 reference

A novel panel of cerebrospinal fluid biomarkers for the differential diagnosis of Alzheimer's disease versus normal aging and frontotemporal dementia

21 January 2018

1 reference

Cerebrospinal fluid proteomic biomarkers for Alzheimer's disease.

21 January 2018

1 reference

Novel panel of cerebrospinal fluid biomarkers for the prediction of progression to Alzheimer dementia in patients with mild cognitive impairment

21 January 2018

1 reference

The art of observing rare protein species in proteomes with peptide ligand libraries

21 January 2018

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In-depth exploration of cerebrospinal fluid by combining peptide ligand library treatment and label-free protein quantification

21 January 2018

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The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14

21 January 2018

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miRNA genetic alterations in human cancers

21 January 2018

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Multilevel regulation of gene expression by microRNAs

21 January 2018

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Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

21 January 2018

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Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus.

21 January 2018

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The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

21 January 2018

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

21 January 2018

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An NF-kappaB-sensitive micro RNA-146a-mediated inflammatory circuit in Alzheimer disease and in stressed human brain cells

21 January 2018

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Micro-RNA abundance and stability in human brain: specific alterations in Alzheimer's disease temporal lobe neocortex.

21 January 2018

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Neuronal microRNA deregulation in response to Alzheimer's disease amyloid-beta

21 January 2018

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