MLL-SEPTIN gene fusions in hematological malignancies (Q37895709)

24 August 2017

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title

MLL-SEPTIN gene fusions in hematological malignancies (English)

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24 August 2017

1

Nuno Cerveira

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24 August 2017

Manuel R Teixeira

3

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author name string

Susana Bizarro

series ordinal

2

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24 August 2017

language of work or name

English

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publication date

30 June 2011

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24 August 2017

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24 August 2017

volume

392

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24 August 2017

issue

8-9

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24 August 2017

page(s)

713-724

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Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.072

Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.072

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.072

An ins(X;11)(q24;q23) fuses the MLL and the Septin 6/KIAA0128 gene in an infant with AML-M2.

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.072

Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

21 January 2018

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https://api.crossref.org/works/10.1515%2FBC.2011.072

Therapeutic advances in acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

SEPT2 is a new fusion partner of MLL in acute myeloid leukemia with t(2;11)(q37;q23).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Molecular characterization of the MLL-SEPT6 fusion gene in acute myeloid leukemia: identification of novel fusion transcripts and cloning of genomic breakpoint junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

A novel MLL-SEPT2 fusion variant in therapy-related myelodysplastic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Both SEPT2 and MLL are down-regulated in MLL-SEPT2 therapy-related myeloid neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Positional cloning of the gene for multiple endocrine neoplasia-type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The versatile mixed lineage leukaemia gene MLL and its many associations in leukaemogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Complex and cryptic chromosomal rearrangements involving the MLL gene in acute leukemia: a study of 7 patients and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Mll rearrangements in haematological malignancies: lessons from clinical and biological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The AF10 leucine zipper is required for leukemic transformation of myeloid progenitors by MLL-AF10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Protein interactions of the MLL PHD fingers modulate MLL target gene regulation in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Molecular analysis of t(X;11)(q24;q23) in an infant with AML‐M4

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Seeking truth on Monte Verita. Workshop on the molecular biology and biochemistry of septins and septin function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The pathophysiology of HOX genes and their role in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The pathobiology of the septin gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Expression profiling the human septin gene family

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL: a histone methyltransferase disrupted in leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL-SEPT6 fusion transcript with a novel sequence in an infant with acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL/SEPTIN6 chimeric transcript from inv ins(X;11)(q24;q23q13) in acute monocytic leukemia: report of a case and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

An MLL-SEPT9 fusion and t(11;17)(q23;q25) associated with de novo myelodysplastic syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL translocations, histone modifications and leukaemia stem-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Classification and evolution of P-loop GTPases and related ATPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Biphasic MLL takes helm at cell cycle control: implications in human mixed lineage leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Mixed lineage leukemia: histone H3 lysine 4 methyltransferases from yeast to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Mixed lineage leukemia: roles in human malignancies and potential therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Mechanisms of leukemogenesis by MLL fusion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The MLL recombinome of acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

New insights to the MLL recombinome of acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL targets SET domain methyltransferase activity to Hox gene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL associates specifically with a subset of transcriptionally active target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The PHD fingers of MLL block MLL fusion protein-mediated transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MSF (MLL septin-like fusion), a fusion partner gene of MLL, in a therapy-related acute myeloid leukemia with a t(11;17)(q23;q25)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

CASP8AP2 is a novel partner gene of MLL rearrangement with t(6;11)(q15;q23) in acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Characterization of a SEPT9 interacting protein, SEPT14, a novel testis-specific septin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL: how complex does it get?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Topoisomerase II inhibitor-related acute myeloid leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Frequent chromosomal translocations induced by DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Favorable impact of the t(9;11) in childhood acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Do septins have a role in cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Expression pattern of the septin gene family in acute myeloid leukemias with and without MLL-SEPT fusion genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Structural insight into filament formation by mammalian septins

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The molecular biology of mixed lineage leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

MLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisom

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Translocation (2;11)(q37;q23) in therapy-related myelodysplastic syndrome after treatment for acute promyelocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Dimerization contributes to oncogenic activation of MLL chimeras in acute leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Here come the septins: novel polymers that coordinate intracellular functions and organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

A translocation in acute lymphoblastic leukemia that cytogenetically mimics the recurrent MLL-AFF1 translocation and fuses SEPT11 to MLL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Dietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

11q23/MLL acute leukemia : update of clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The CDCREL1 gene fused to MLL in de novo acute myeloid leukemia with t(11;22)(q23;q11.2) and its frequent expression in myeloid leukemia cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Histone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

A new subtype of MLL-SEPT2 fusion transcript in therapy-related acute myeloid leukemia with t(2;11)(q37;q23): a case report and literature review

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Some assembly required: yeast septins provide the instruction manual

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Persistent transactivation by meis1 replaces hox function in myeloid leukemogenesis models: evidence for co-occupancy of meis1-pbx and hox-pbx complexes on promoters of leukemia-associated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

The septin family of GTPases: architecture and dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Fusion of MLL and MSF in adult de novo acute myelomonocytic leukemia (M4) with t(11;17)(q23;q25)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Nuclear punctate distribution of ALL-1 is conferred by distinct elements at the N terminus of the protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Leukemia proto-oncoprotein MLL is proteolytically processed into 2 fragments with opposite transcriptional properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Menin critically links MLL proteins with LEDGF on cancer-associated target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Hoxa9 and Meis1 are key targets for MLL-ENL-mediated cellular immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FBC.2011.072

21 January 2018

Identifiers

DOI

10.1515/BC.2011.072

1 reference

release_v7zbtgu7xbfzbc3tb2apxi6ce4

24 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/v7zbtgu7xbfzbc3tb2apxi6ce4

mapped directly with Wikidata item

24 November 2022

based on heuristic

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