A new frontier in personalized cancer therapy: mapping molecular changes. (Q37898108)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732758%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

review article

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title

A new frontier in personalized cancer therapy: mapping molecular changes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732758%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2

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6 February 2020

author name string

Katayoon Kasaian

series ordinal

1

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6 February 2020

language of work or name

English

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publication date

1 July 2011

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6 February 2020

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6 February 2020

volume

7

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6 February 2020

issue

7

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6 February 2020

page(s)

873-894

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Future of personalized medicine in oncology: a systems biology approach

6 February 2020

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Identification of microRNA-21 as a biomarker for chemoresistance and clinical outcome following adjuvant therapy in resectable pancreatic cancer

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Silencing of microRNAs in vivo with 'antagomirs'

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21 January 2018

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MicroRNA gene expression deregulation in human breast cancer

21 January 2018

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A microRNA expression signature of human solid tumors defines cancer gene targets

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Preparation and analysis of microRNA libraries using the Illumina massively parallel sequencing technology.

21 January 2018

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TID1, a human homolog of the Drosophila tumor suppressor l(2)tid, encodes two mitochondrial modulators of apoptosis with opposing functions

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Identification and characterization of soluble isoform of fibroblast growth factor receptor 3 in human SaOS-2 osteosarcoma cells

21 January 2018

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Alternative expression analysis by RNA sequencing

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Microarray analysis of alternative splicing.

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A microarray configuration to quantify expression levels and relative abundance of splice variants

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Transcriptome sequencing to detect gene fusions in cancer

21 January 2018

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MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

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Proteomic strategies for individualizing therapy of acute myeloid leukemia (AML).

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Analysing differential gene expression in cancer.

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Protein profiling of microdissected prostate tissue links growth differentiation factor 15 to prostate carcinogenesis

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A 25-signal proteomic signature and outcome for patients with resected non-small-cell lung cancer.

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Protein chip technology

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The grand challenge to decipher the cancer proteome.

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Glycoproteomics and glycomics investigation of membrane N-glycosylproteins from human colon carcinoma cells

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Towards an integrated proteomic and glycomic approach to finding cancer biomarkers

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21 January 2018

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Human drug-metabolizing enzyme polymorphisms: effects on risk of toxicity and cancer

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Drug reactions enzymes, and biochemical genetics

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

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Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs

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Pharmacogenetics and cancer therapy

21 January 2018

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Mechanisms of resistance to anticancer drugs: the role of the polymorphic ABC transporters ABCB1 and ABCG2.

21 January 2018

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Methylenetetrahydrofolate reductase gene polymorphisms and response to fluorouracil-based treatment in advanced colorectal cancer patients.

21 January 2018

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CYP2D6 polymorphisms and the impact on tamoxifen therapy

21 January 2018

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Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia

21 January 2018

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HR23B is a biomarker for tumor sensitivity to HDAC inhibitor-based therapy

21 January 2018

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Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer

21 January 2018

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Translation of the Philadelphia chromosome into therapy for CML.

21 January 2018

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Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia

21 January 2018

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Frequency of major molecular responses to imatinib or interferon alfa plus cytarabine in newly diagnosed chronic myeloid leukemia

21 January 2018

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Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

21 January 2018

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Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia

21 January 2018

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Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl.

21 January 2018

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Toxicity and response criteria of the Eastern Cooperative Oncology Group

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Nilotinib: evaluation and analysis of its role in chronic myeloid leukemia

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21 January 2018

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

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Trastuzumab as adjuvant systemic therapy for HER2-positive breast cancer

21 January 2018

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Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis

21 January 2018

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Metabolism, excretion, and pharmacokinetics of [14C]INCB018424, a selective Janus tyrosine kinase 1/2 inhibitor, in humans

21 January 2018

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

21 January 2018

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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

21 January 2018

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

21 January 2018

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Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

21 January 2018

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

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Cancer research. Melanoma drug vindicates targeted approach.

21 January 2018

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Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics

21 January 2018

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Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer

21 January 2018

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Screening for epidermal growth factor receptor mutations in lung cancer

21 January 2018

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Detection of mutations in EGFR in circulating lung-cancer cells

21 January 2018

1 reference

Gefitinib as first-line treatment for patients with advanced non-small-cell lung cancer with activating epidermal growth factor receptor mutation: Review of the evidence

21 January 2018

1 reference

Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib

21 January 2018

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KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer.

21 January 2018

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Genetics: Predictive value of KRAS mutations in chemoresistant CRC.

21 January 2018

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Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer

21 January 2018

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K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

21 January 2018

1 reference

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

21 January 2018

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Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

21 January 2018

1 reference

Mechanisms and implications of imatinib resistance mutations in BCR-ABL.

21 January 2018

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Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer

21 January 2018

1 reference

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

21 January 2018

1 reference

EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors.

21 January 2018

1 reference

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

1 reference

Methods for analysis in pharmacogenomics: lessons from the Pharmacogenetics Research Network Analysis Group

21 January 2018

1 reference

Randomized clinical trials with biomarkers: design issues

21 January 2018

1 reference

Personalized medicine in oncology: the future is now.

21 January 2018

1 reference

Clinical trial designs for predictive biomarker validation: theoretical considerations and practical challenges.

21 January 2018

1 reference

Genomic and personalized medicine: foundations and applications

21 January 2018

1 reference

The ClinSeq Project: piloting large-scale genome sequencing for research in genomic medicine

21 January 2018

1 reference

Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary

21 January 2018

1 reference

ALEXA: a microarray design platform for alternative expression analysis

21 January 2018

1 reference

Tumour-associated E-cadherin mutations alter cellular morphology, decrease cellular adhesion and increase cellular motility

21 January 2018

1 reference

Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification

21 January 2018

1 reference

Genetic mapping of a second locus predisposing to hereditary non–polyposis colon cancer

21 January 2018

1 reference

21 January 2018

The human genome at ten

1 reference

Starch Gel Electrophoresis Studies on Abnormal Proteins in Myeloma and Macroglobulinæmia

21 January 2018

1 reference

Personalized cancer therapy gets closer

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.2217/FON.11.63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21732758%20AND%20SRC:MED&resulttype=core&format=json

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6 February 2020

Fatcat ID

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24 November 2022

based on heuristic

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