SOD1 and mitochondria in ALS: a dangerous liaison. (Q37955818)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

SOD1 and mitochondria in ALS: a dangerous liaison (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

amyotrophic lateral sclerosis

16 January 2020

main subject

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

Mauro Cozzolino

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

author name string

Maria Teresa Carrì

series ordinal

1

1 reference

25 August 2017

Mauro Cozzolino

series ordinal

2

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25 August 2017

language of work or name

1 reference

1 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

Journal of Bioenergetics and Biomembranes

16 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

volume

43

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22081209%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

page(s)

593-599

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https://scigraph.springernature.com/pub.10.1007/s10863-011-9394-z

16 January 2020

exact match

0 references

cites work

Mitochondrial damage due to SOD1 deficiency in SH-SY5Y neuroblastoma cells: a rationale for the redundancy of SOD1

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Inactivation of cytochrome c oxidase by mutant SOD1s in mouse motoneuronal NSC-34 cells is independent from copper availability but is because of nitric oxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Lessons from models of SOD1-linked familial ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Overloading of stable and exclusion of unstable human superoxide dismutase-1 variants in mitochondria of murine amyotrophic lateral sclerosis models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Expression of a Cu,Zn superoxide dismutase typical of familial amyotrophic lateral sclerosis induces mitochondrial alteration and increase of cytosolic Ca2+ concentration in transfected neuroblastoma SH-SY5Y cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Targets in ALS: designing multidrug therapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial dynamics--fusion, fission, movement, and mitophagy--in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Cysteine 111 affects aggregation and cytotoxicity of mutant Cu,Zn-superoxide dismutase associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Amyotrophic lateral sclerosis: from current developments in the laboratory to clinical implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Oligomerization of mutant SOD1 in mitochondria of motoneuronal cells drives mitochondrial damage and cell toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Role of axonal transport in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitophagy and Parkinson's disease: the PINK1-parkin link.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Conversion to the amyotrophic lateral sclerosis phenotype is associated with intermolecular linked insoluble aggregates of SOD1 in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Familial ALS-superoxide dismutases associate with mitochondria and shift their redox potentials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Factors controlling the uptake of yeast copper/zinc superoxide dismutase into mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Calcium dysregulation in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

The intermembrane space of mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1G93A mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial membrane permeabilization in cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutant SOD1 and mitochondrial damage alter expression and splicing of genes controlling neuritogenesis in models of neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Toxicity of familial ALS-linked SOD1 mutants from selective recruitment to spinal mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutant SOD1 in neuronal mitochondria causes toxicity and mitochondrial dynamics abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Motor neuron degeneration in amyotrophic lateral sclerosis mutant superoxide dismutase-1 transgenic mice: mechanisms of mitochondriopathy and cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial dysfunction in a cell culture model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial protein oxidation in yeast mutants lacking manganese-(MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD): evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Axonal swellings in the corticospinal tracts in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Caspase-1 and -3 are sequentially activated in motor neuron death in Cu,Zn superoxide dismutase-mediated familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

The disulfide relay system of mitochondria is required for the biogenesis of mitochondrial Ccs1 and Sod1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial protein import: from proteomics to functional mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mitochondrial dysfunction in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Influence of aging on membrane permeability transition in brain mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Selective association of misfolded ALS-linked mutant SOD1 with the cytoplasmic face of mitochondria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10863-011-9394-Z

Increase of Cu,Zn-superoxide dismutase activity during differentiation of human K562 cells involves activation by copper of a constantly expressed copper-deficient protein

21 January 2018

1 reference

12 December 2020

Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis

1 reference

12 December 2020

Mitochondrial dysfunction is a converging point of multiple pathological pathways in amyotrophic lateral sclerosis

1 reference

12 December 2020

Increased autophagy in transgenic mice with a G93A mutant SOD1 gene

1 reference

12 December 2020

Bcl2a1 serves as a switch in death of motor neurons in amyotrophic lateral sclerosis

1 reference

12 December 2020

Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization

1 reference

12 December 2020

Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis

1 reference

12 December 2020

CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations

1 reference

12 December 2020

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

1 reference

12 December 2020

Induction of parkinsonism-related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene

1 reference

12 December 2020

Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS

1 reference

12 December 2020

Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function

1 reference

12 December 2020

Isolated cerebral and cerebellar mitochondria produce free radicals when exposed to elevated CA2+ and Na+: implications for neurodegeneration

1 reference

12 December 2020

Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis

1 reference

12 December 2020

Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation

1 reference

12 December 2020

In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress

1 reference

12 December 2020

Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis

1 reference

12 December 2020