Recent rodent models for Alzheimer's disease: clinical implications and basic research (Q37956513)

25 August 2017

title

Recent rodent models for Alzheimer's disease: clinical implications and basic research (English)

1 reference

25 August 2017

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Adrian G Palacios

3

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Roger Chung

object named as

Roger S Chung

6

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Gilles J. Guillemin

object named as

Gilles J Guillemin

8

0 references

Perminder Sachdev

object named as

Perminder Sachdev

7

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author name string

Nady Braidy

1

1 reference

25 August 2017

Pablo Muñoz

2

1 reference

25 August 2017

Gloria Castellano-Gonzalez

4

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25 August 2017

Nibaldo C Inestrosa

5

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25 August 2017

publication date

16 November 2011

1 reference

Journal of Neural Transmission

25 August 2017

published in

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25 August 2017

volume

119

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25 August 2017

issue

2

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25 August 2017

page(s)

173-195

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Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

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A beta40 is a major form of beta-amyloid in nonhuman primates

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Presenilins as therapeutic targets for the treatment of Alzheimer's disease

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Effects of β-amyloid protein on serotoninergic, noradrenergic, and cholinergic markers in neurons of the pontomesencephalic tegmentum in the rat

21 January 2018

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Animal models of Alzheimer's disease and frontotemporal dementia

21 January 2018

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Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice

21 January 2018

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Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

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21 January 2018

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21 January 2018

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21 January 2018

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Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update

21 January 2018

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Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

21 January 2018

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Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice

21 January 2018

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APP processing and synaptic function

21 January 2018

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21 January 2018

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Progressive age-related impairment of cognitive behavior in APP23 transgenic mice

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Aging and time-of-day effects on anxiety in female Octodon degus.

21 January 2018

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21 January 2018

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Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

21 January 2018

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Alzheimer's disease: the cholesterol connection

21 January 2018

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21 January 2018

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The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

21 January 2018

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21 January 2018

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21 January 2018

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Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

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Causative and susceptibility genes for Alzheimer's disease: a review.

21 January 2018

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Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

21 January 2018

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Canine counterpart of senile dementia of the Alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages

21 January 2018

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Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

21 January 2018

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Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain

21 January 2018

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Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway

21 January 2018

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The canine sand maze: an appetitive spatial memory paradigm sensitive to age-related change in dogs.

21 January 2018

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The canine cognitive dysfunction rating scale (CCDR): a data-driven and ecologically relevant assessment tool

21 January 2018

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Natural non-trasgenic animal models for research in Alzheimer's disease

21 January 2018

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The progression of beta-amyloid deposition in the frontal cortex of the aged canine

21 January 2018

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Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

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A beta immunotherapy: Lessons learned for potential treatment of Alzheimer's disease

21 January 2018

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Amyloid peptides are toxic via a common oxidative mechanism

21 January 2018

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21 January 2018

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Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats

21 January 2018

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The effect of aging on pars compacta of the substantia nigra in rhesus monkey

21 January 2018

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Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

21 January 2018

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Body size, energy metabolism and lifespan

21 January 2018

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Transgenic models of Alzheimer's disease: learning from animals

21 January 2018

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The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation

21 January 2018

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Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

21 January 2018

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Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau.

21 January 2018

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Age-dependent cognitive decline in the APP23 model precedes amyloid deposition

21 January 2018

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21 January 2018

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Proteolytic mechanisms in amyloid-beta metabolism: therapeutic implications for Alzheimer's disease

21 January 2018

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Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

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Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

21 January 2018

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Short-term synaptic plasticity

21 January 2018

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21 January 2018

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Familial influence on plaque formation in the beagle brain

21 January 2018

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12 December 2020

Expressions of Abeta1-40, Abeta1-42, tau202, tau396 and tau404 after intracerebroventricular injection of streptozotocin in rats

1 reference

12 December 2020

Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys.

1 reference

12 December 2020

Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology

1 reference

12 December 2020

Early changes in neurons of the hippocampus and neocortex in transgenic rats expressing intracellular human a-beta.

1 reference

12 December 2020

Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.

1 reference

12 December 2020

Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.

1 reference

12 December 2020

The pathology of APP transgenic mice: a model of Alzheimer's disease or simply overexpression of APP?

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12 December 2020

General and dramatic glial reaction in Alzheimer brains

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12 December 2020

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

1 reference

12 December 2020

Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys

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12 December 2020

Nonhuman primates as models for aging and Alzheimer's disease

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12 December 2020

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

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12 December 2020

Animal models of cerebral beta-amyloid angiopathy

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12 December 2020

A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels

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12 December 2020

Transgenic mouse models of Alzheimer's disease: phenotype and application

1 reference

12 December 2020

α1-Antichymotrypsin is present together with the β-protein in monkey brain amyloid deposits

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

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12 December 2020

Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

1 reference

12 December 2020

Pathways towards and away from Alzheimer's disease

1 reference

12 December 2020

Temporal and spatial relationship between the death of PrP-damaged neurones and microglial activation

1 reference

12 December 2020

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein

1 reference

12 December 2020

Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease.

1 reference

12 December 2020

[Animal models of Alzheimer's disease: a road full of pitfalls].

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12 December 2020

Carboxyl end-specific monoclonal antibodies to amyloid beta protein (A beta) subtypes (A beta 40 and A beta 42(43)) differentiate A beta in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys

1 reference

12 December 2020

Filamentous tau pathology in nerve cells, astrocytes, and oligodendrocytes of aged baboons

1 reference

12 December 2020

Expansion of the Golgi apparatus in rat cerebral cortex following intracerebroventricular injections of streptozotocin.

1 reference

12 December 2020

Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide

1 reference

12 December 2020

Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta lowering activity in a transgenic mouse model of Al

1 reference

12 December 2020

Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein

1 reference

12 December 2020

Abnormal neuronal and glial argyrophilic fibrillary structures in the brain of an aged albino cynomolgus monkey (Macaca fascicularis)

1 reference

12 December 2020

10.1007/S00702-011-0731-5

Identifiers

DOI

1 reference

25 August 2017

1 reference