Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function (Q37970188)

26 August 2017

Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function (English)

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26 August 2017

Andrew J Hoy

2

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author name string

Matthew J Watt

series ordinal

1

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26 August 2017

20 December 2011

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American Journal of Physiology - Endocrinology and Metabolism

26 August 2017

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26 August 2017

302

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26 August 2017

E1315-28

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26 August 2017

11

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Chronic hyperglycaemia promotes lipogenesis and triacylglycerol accumulation in human skeletal muscle cells

26 August 2017

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide content is increased in skeletal muscle from obese insulin-resistant humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Pharmacological inhibition of glucosylceramide synthase enhances insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Skeletal muscle triglycerides, diacylglycerols, and ceramides in insulin resistance: another paradox in endurance-trained athletes?

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Two pathways for lysophosphatidic acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide and ceramide 1-phosphate in health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Exercise increases plasma levels of sphingoid base-1 phosphates in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Dynamic activity of lipid droplets: protein phosphorylation and GTP-mediated protein translocation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Thermodynamics and mechanics of membrane curvature generation and sensing by proteins and lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipid partitioning, incomplete fatty acid oxidation, and insulin signal transduction in primary human muscle cells: effects of severe obesity, fatty acid incubation, and fatty acid translocase/CD36 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effects of sphingosine 1-phosphate on excitation-contraction coupling in mammalian skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Increased levels of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1alpha) improve lipid utilisation, insulin signalling and glucose transport in skeletal muscle of lean and insulin-resistant obese Zucker rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effect of 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion on in vivo glucose and lipid metabolism in lean and obese Zucker rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Trafficking of dietary fat in lean rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effect of exercise duration on the key pathways of ceramide metabolism in rat skeletal muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Plasma membrane subdomain compartmentalization contributes to distinct mechanisms of ceramide action on insulin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Pigment epithelium-derived factor regulates lipid metabolism via adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Pleiotropic effects of sphingolipids in skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

TIP47 functions in the biogenesis of lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

A novel function for fatty acid translocase (FAT)/CD36: involvement in long chain fatty acid transfer into the mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Dilinoleoyl-phosphatidic acid mediates reduced IRS-1 tyrosine phosphorylation in rat skeletal muscle cells and mouse muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Insulin resistance is associated with higher intramyocellular triglycerides in type I but not type II myocytes concomitant with higher ceramide content

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipins: multifunctional lipid metabolism proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipophilin protein expression in muscle--a possible protective role against insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

FATP4 contributes as an enzyme to the basal and insulin-mediated fatty acid uptake of C₂C₁₂ muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effect of acute exercise on the content of free sphinganine and sphingosine in different skeletal muscle types of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Exercise-induced alterations in intramyocellular lipids and insulin resistance: the athlete's paradox revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Insulin increases FA uptake and esterification but reduces lipid utilization in isolated contracting muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Phosphatidic acid-mediated mitogenic activation of mTOR signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide as a TLR4 agonist; a putative signalling intermediate between sphingolipid receptors for microbial ligands and TLR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sphingosine 1-phosphate induces cell contraction via calcium-independent/Rho-dependent pathways in undifferentiated skeletal muscle cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation of transient receptor potential canonical channel 1 (TRPC1) by sphingosine 1-phosphate in C2C12 myoblasts and its relevance for a role of mechanotransduction in skeletal muscle differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sphingolipids: the nexus between Gaucher disease and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Local factors modulate tissue-specific NEFA utilization: assessment in rats using 3H-(R)-2-bromopalmitate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

An update on sphingosine-1-phosphate and other sphingolipid mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Control of metabolism and signaling of simple bioactive sphingolipids: Implications in disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Modulation of pro-inflammatory gene expression by nuclear lysophosphatidic acid receptor type-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Functional interactions between Mldp (LSDP5) and Abhd5 in the control of intracellular lipid accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

FATP1 channels exogenous FA into 1,2,3-triacyl-sn-glycerol and down-regulates sphingomyelin and cholesterol metabolism in growing 293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effects of weight loss and physical activity on muscle lipid content and droplet size

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

FAT/CD36-null mice reveal that mitochondrial FAT/CD36 is required to upregulate mitochondrial fatty acid oxidation in contracting muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipose triacylglycerol lipase deletion alters whole body energy metabolism and impairs exercise performance in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Dietary fats and membrane function: implications for metabolism and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lysophosphatidic acid mediates pleiotropic responses in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

FAT/CD36 is localized in sarcolemma and in vesicle-like structures in subsarcolemma regions but not in mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Relationship between plasma free fatty acid, intramyocellular triglycerides and long-chain acylcarnitines in resting humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

The stoichiometry of protein phosphorylation in adipocyte lipid droplets: analysis by N-terminal isotope tagging and enzymatic dephosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effect of exercise training on muscle glucose transporter 4 protein and intramuscular lipid content in elderly men with impaired glucose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

PKC-theta knockout mice are protected from fat-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipolysis - a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipocyte differentiation-related protein reduces the lipid droplet association of adipose triglyceride lipase and slows triacylglycerol turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Long-chain fatty acid uptake by skeletal muscle is impaired in homozygous, but not heterozygous, heart-type-FABP null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Roles of peroxisome proliferator-activated receptor delta (PPARdelta) in the control of fatty acid catabolism. A new target for the treatment of metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Long-chain acyl-CoA synthetases and fatty acid channeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Rat long-chain acyl-CoA synthetase mRNA, protein, and activity vary in tissue distribution and in response to diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Functional interaction between TRPC1 channel and connexin-43 protein: a novel pathway underlying S1P action on skeletal myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Permissive role of protein kinase C alpha but not protein kinase C delta in sphingosine 1-phosphate-induced Rho A activation in C2C12 myoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipocyte differentiation-related protein and OXPAT in rat and human skeletal muscle: involvement in lipid accumulation and type 2 diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

DAG accumulation from saturated fatty acids desensitizes insulin stimulation of glucose uptake in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Entry of muscle satellite cells into the cell cycle requires sphingolipid signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Greater transport efficiencies of the membrane fatty acid transporters FAT/CD36 and FATP4 compared with FABPpm and FATP1 and differential effects on fatty acid esterification and oxidation in rat skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sphingolipid metabolism, oxidant signaling, and contractile function of skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Skeletal muscle triglyceride levels are inversely related to insulin action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Increased beta-oxidation in muscle cells enhances insulin-stimulated glucose metabolism and protects against fatty acid-induced insulin resistance despite intramyocellular lipid accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation of sphingosine kinase and sphingolipid signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Glycerolipid metabolism and signaling in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sphingosine 1-phosphate increases glucose uptake through trans-activation of insulin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

mTOR function in skeletal muscle: a focal point for overnutrition and exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mechanism of free fatty acid-induced insulin resistance in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Sex differences in hormone-sensitive lipase expression, activity, and phosphorylation in skeletal muscle at rest and during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Long-term synaptic changes induced in the cerebellar cortex by fear conditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

High triacylglycerol turnover rate in human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Intramuscular fatty acid metabolism in contracting and non-contracting human skeletal muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Altered adipose and plasma sphingolipid metabolism in obesity: a potential mechanism for cardiovascular and metabolic risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Extracellular signal-regulated kinase-1 and -2 respond differently to mitogenic and differentiative signaling pathways in myoblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Activation of the Drosophila MLK by ceramide reveals TNF-alpha and ceramide as agonists of mammalian MLK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acid-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Novel role of FATP1 in mitochondrial fatty acid oxidation in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Electron transport chain-dependent and -independent mechanisms of mitochondrial H2O2 emission during long-chain fatty acid oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Transgenic mice with dominant negative PKC-theta in skeletal muscle: a new model of insulin resistance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Perilipins are associated with cholesteryl ester droplets in steroidogenic adrenal cortical and Leydig cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Network distribution of mitochondria and lipid droplets in human muscle fibres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Heart-type fatty acid-binding protein reciprocally regulates glucose and fatty acid utilization during exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lipid metabolic enzymes: emerging drug targets for the treatment of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

From dynamic live cell imaging to 3D ultrastructure: novel integrated methods for high pressure freezing and correlative light-electron microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ceramide-rich platforms in transmembrane signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

III. Electron microscopic radioautographic study of the rat heart perfused with tritiated oleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Relationship between insulin sensitivity and sphingomyelin signaling pathway in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Identification and characterization of associated with lipid droplet protein 1: A novel membrane-associated protein that resides on hepatic lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effect of the antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Inhibition of ADRP prevents diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Activation of hormone-sensitive lipase requires two steps, protein phosphorylation and binding to the PAT-1 domain of lipid droplet coat proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Modulating serine palmitoyl transferase (SPT) expression and activity unveils a crucial role in lipid-induced insulin resistance in rat skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Effects of dynamic exercise intensity on the activation of hormone-sensitive lipase in human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance by attenuating ceramide accumulation and phosphorylation of c-Jun N-terminal kinase in peripheral tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Regulation and function of triacylglycerol lipases in cellular metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Fatty acid incubation of myotubes from humans with type 2 diabetes leads to enhanced release of beta-oxidation products because of impaired fatty acid oxidation: effects of tetradecylthioacetic acid and eicosapentaenoic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Adipocyte protein S3-12 coats nascent lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mechanisms of the lysophosphatidic acid-induced increase in [Ca(2+)](i) in skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Enhanced insulin sensitivity in mice lacking ganglioside GM3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

The G(0)/G(1) switch gene 2 regulates adipose lipolysis through association with adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Lysophosphatidic acid regulates blood glucose by stimulating myotube and adipocyte glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Proteome of skeletal muscle lipid droplet reveals association with mitochondria and apolipoprotein a-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00561.2011

10.1152/AJPENDO.00561.2011

21 January 2018

Identifiers

DOI

1 reference

26 August 2017

1 reference

PubMed ID

22185843