Shaping development with ESCRTs (Q37970884)

26 August 2017

Shaping development with ESCRTs (English)

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26 August 2017

3

Harald Stenmark

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26 August 2017

Thomas Vaccari

2

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Tor Erik Rusten

object named as

Tor Erik Rusten

series ordinal

1

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publication date

22 December 2011

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26 August 2017

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26 August 2017

14

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26 August 2017

1

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26 August 2017

38-45

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https://scigraph.springernature.com/pub.10.1038/ncb2381

26 August 2017

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cites work

Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

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Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

21 January 2018

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

21 January 2018

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Evolution of the multivesicular body ESCRT machinery; retention across the eukaryotic lineage

21 January 2018

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The ESCRT complexes: structure and mechanism of a membrane-trafficking network

21 January 2018

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Membrane budding and scission by the ESCRT machinery: it's all in the neck

21 January 2018

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The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

21 January 2018

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ESCRTing proteins in the endocytic pathway

21 January 2018

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The emerging shape of the ESCRT machinery

21 January 2018

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Molecular mechanism of multivesicular body biogenesis by ESCRT complexes

21 January 2018

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Breaking the chains: structure and function of the deubiquitinases

21 January 2018

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Membrane scission by the ESCRT-III complex

21 January 2018

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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

21 January 2018

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Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila

21 January 2018

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Hrs mediates downregulation of multiple signalling receptors in Drosophila

21 January 2018

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Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs

21 January 2018

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Endocytic pathway is required for Drosophila Toll innate immune signaling

21 January 2018

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The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development

21 January 2018

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Tumor suppressor properties of the ESCRT-II complex component Vps25 in Drosophila

21 January 2018

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Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth

21 January 2018

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vps25 mosaics display non-autonomous cell survival and overgrowth, and autonomous apoptosis

21 January 2018

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Disruption of Vps4 and JNK function in Drosophila causes tumour growth

21 January 2018

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The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

21 January 2018

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Vps22/EAP30 in ESCRT-II mediates endosomal sorting of growth factor and chemokine receptors destined for lysosomal degradation

21 January 2018

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Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes

21 January 2018

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TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

21 January 2018

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The ESCRT-III protein CeVPS-32 is enriched in domains distinct from CeVPS-27 and CeVPS-23 at the endosomal membrane of epithelial cells

21 January 2018

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MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation

21 January 2018

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Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster

21 January 2018

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The Drosophila tumor suppressor vps25 prevents nonautonomous overproliferation by regulating notch trafficking

21 January 2018

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Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes

21 January 2018

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Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt

21 January 2018

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Endosomal-sorting complexes required for transport (ESCRT) pathway-dependent endosomal traffic regulates the localization of active Src at focal adhesions

21 January 2018

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The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway

21 January 2018

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A mutation in dVps28 reveals a link between a subunit of the endosomal sorting complex required for transport-I complex and the actin cytoskeleton in Drosophila.

21 January 2018

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Comparative analysis of ESCRT-I, ESCRT-II and ESCRT-III function in Drosophila by efficient isolation of ESCRT mutants

21 January 2018

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Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis

21 January 2018

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CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

21 January 2018

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Loss of hippocampal CA3 pyramidal neurons in mice lacking STAM1.

21 January 2018

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Signal-transducing adaptor molecules STAM1 and STAM2 are required for T-cell development and survival

21 January 2018

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p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101.

21 January 2018

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Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations

21 January 2018

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ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration

21 January 2018

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Functional interactions between the erupted/tsg101 growth suppressor gene and the DaPKC and rbf1 genes in Drosophila imaginal disc tumors

21 January 2018

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Proteolytic processing of protocadherin proteins requires endocytosis

21 January 2018

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The TSG101 protein binds to connexins and is involved in connexin degradation.

21 January 2018

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Ubiquitylation of the gap junction protein connexin-43 signals its trafficking from early endosomes to lysosomes in a process mediated by Hrs and Tsg101

21 January 2018

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Non-muscle myosin II takes centre stage in cell adhesion and migration

21 January 2018

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Autophagy fights disease through cellular self-digestion

21 January 2018

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Isolation and characterization of rat liver amphisomes. Evidence for fusion of autophagosomes with both early and late endosomes

21 January 2018

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Microautophagy of cytosolic proteins by late endosomes

21 January 2018

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CeVPS-27 is an endosomal protein required for the molting and the endocytic trafficking of the low-density lipoprotein receptor-related protein 1 in Caenorhabditis elegans

21 January 2018

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ESCRTs and Fab1 regulate distinct steps of autophagy

21 January 2018

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Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease

21 January 2018

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Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

21 January 2018

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Inhibition of autophagy induction delays neuronal cell loss caused by dysfunctional ESCRT-III in frontotemporal dementia

21 January 2018

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Autophagy, not apoptosis, is essential for midgut cell death in Drosophila

21 January 2018

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Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

21 January 2018

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Human ESCRT-III and VPS4 proteins are required for centrosome and spindle maintenance

21 January 2018

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Parallels between cytokinesis and retroviral budding: a role for the ESCRT machinery

21 January 2018

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Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.

21 January 2018

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Plk1 negatively regulates Cep55 recruitment to the midbody to ensure orderly abscission

21 January 2018

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Human ESCRT and ALIX proteins interact with proteins of the midbody and function in cytokinesis

21 January 2018

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Dynamics of endosomal sorting complex required for transport (ESCRT) machinery during cytokinesis and its role in abscission

21 January 2018

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Cortical constriction during abscission involves helices of ESCRT-III-dependent filaments

21 January 2018

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PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

21 January 2018

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Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

21 January 2018

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Essential role of Pin1 in the regulation of TRF1 stability and telomere maintenance

21 January 2018

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bicoid RNA localization requires specific binding of an endosomal sorting complex

21 January 2018

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ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

21 January 2018

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Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain

21 January 2018

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A Role for the ESCRT System in Cell Division in Archaea

21 January 2018

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Molecular and structural basis of ESCRT-III recruitment to membranes during archaeal cell division

21 January 2018

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A unique cell division machinery in the Archaea.

21 January 2018

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GISP binding to TSG101 increases GABA receptor stability by down-regulating ESCRT-mediated lysosomal degradation

21 January 2018

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TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes

21 January 2018

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ATPase-defective mammalian VPS4 localizes to aberrant endosomes and impairs cholesterol trafficking

21 January 2018

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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

21 January 2018

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Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

21 January 2018

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

21 January 2018

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The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation

21 January 2018

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Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release

21 January 2018

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Distinct functions of human MVB12A and MVB12B in the ESCRT-I dependent on their posttranslational modifications

21 January 2018

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Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting

21 January 2018

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Internalization is required for proper Wingless signaling in Drosophila melanogaster

21 January 2018

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Host factors involved in retroviral budding and release.

21 January 2018

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How do ESCRT proteins control autophagy?

21 January 2018

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Silencing by small RNAs is linked to endosomal trafficking

21 January 2018

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12 December 2020

The ESCRT machinery mediates polarization of fibroblasts through regulation of myosin light chain

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12 December 2020

FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes

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12 December 2020

The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis

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12 December 2020

Identifiers

DOI

10.1038/NCB2381

1 reference

26 August 2017

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PubMed ID

22193162