Histone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis (Q37970955)

26 August 2017

title

Histone acetyltransferases and deacetylases: molecular and clinical implications to gastrointestinal carcinogenesis (English)

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26 August 2017

1 reference

Wei-Jian Sun

1

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26 August 2017

Xiang Zhou

2

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26 August 2017

Ji-Hang Zheng

3

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26 August 2017

Ming-Dong Lu

4

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26 August 2017

Jian-Yun Nie

5

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26 August 2017

Xiang-Jiao Yang

6

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26 August 2017

Zhi-Qiang Zheng

7

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26 August 2017

publication date

1 January 2012

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Acta Biochimica et Biophysica Sinica

26 August 2017

published in

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26 August 2017

volume

44

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26 August 2017

issue

1

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26 August 2017

page(s)

80-91

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Hallmarks of Cancer: The Next Generation

26 August 2017

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Histone deacetylases and cancer

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Multivalent engagement of chromatin modifications by linked binding modules

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Structure and acetyl-lysine recognition of the bromodomain

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Function and selectivity of bromodomains in anchoring chromatin-modifying complexes to promoter nucleosomes.

21 January 2018

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Specific targeting and constitutive association of histone deacetylase complexes during transcriptional repression

21 January 2018

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Independent recruitment in vivo by Gal4 of two complexes required for transcription

21 January 2018

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HDA1 and RPD3 are members of distinct yeast histone deacetylase complexes that regulate silencing and transcription

21 January 2018

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Requirement of Hos2 histone deacetylase for gene activity in yeast

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The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes.

21 January 2018

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Acetylation: a regulatory modification to rival phosphorylation?

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

21 January 2018

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Induction of apoptosis in U937 human leukemia cells by suberoylanilide hydroxamic acid (SAHA) proceeds through pathways that are regulated by Bcl-2/Bcl-XL, c-Jun, and p21CIP1, but independent of p53

21 January 2018

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Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

21 January 2018

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Histone deacetylase inhibitors: molecular mechanisms of action

21 January 2018

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Saccade dysmetria during functional perturbation of the caudal fastigial nucleus in the monkey.

21 January 2018

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Linking DNA methylation and histone modification: patterns and paradigms

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Chromosomal instability correlates with genome-wide DNA demethylation in human primary colorectal cancers.

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

DNA methylation patterns and epigenetic memory

21 January 2018

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Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia

21 January 2018

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Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

21 January 2018

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Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

New nomenclature for chromatin-modifying enzymes

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone acetyltransferase complexes: one size doesn't fit all

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone-like TAFs within the PCAF histone acetylase complex

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone acetylation and disease

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Roles of SWI/SNF and HATs throughout the dynamic transcription of a yeast glucose-repressible gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Simultaneous recruitment of coactivators by Gcn4p stimulates multiple steps of transcription in vivo

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

p300 and CBP: partners for life and death

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Phosphorylated CREB binds specifically to the nuclear protein CBP

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Acetylation regulates transcription factor activity at multiple levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Acetylation of histones and transcription-related factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The MYST family of histone acetyltransferases and their intimate links to cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Identification of a human histone acetyltransferase related to monocytic leukemia zinc finger protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Ligand-controlled interaction of histone acetyltransferase binding to ORC-1 (HBO1) with the N-terminal transactivating domain of progesterone receptor induces steroid receptor coactivator 1-dependent coactivation of transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Tip60 in DNA damage response and growth control: many tricks in one HAT.

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Males absent on the first (MOF): from flies to humans.

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

HDAC family: What are the cancer relevant targets?

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Class I histone deacetylase expression has independent prognostic impact in human colorectal cancer: specific role of class I histone deacetylases in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Deletion of histone deacetylase 3 reveals critical roles in S phase progression and DNA damage control

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

HDAC4 promotes growth of colon cancer cells via repression of p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone deacetylase 7 silencing alters endothelial cell migration, a key step in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Class II histone deacetylases play pivotal roles in heat shock protein 90-mediated proteasomal degradation of vascular endothelial growth factor receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Expression profile of histone deacetylase 1 in gastric cancer tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A truncating mutation of HDAC2 in human cancers confers resistance to histone deacetylase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Reduced body size and decreased intestinal tumor rates in HDAC2-mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Increased expression of histone deacetylase 2 is found in human gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Expression of the metastasis-associated MTA1 protein and its relationship to deacetylation of the histone H4 in esophageal squamous cell carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Chromatin and DNA methylation dynamics of Helicobacter pylori-induced COX-2 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Sirtuins in mammals: insights into their biological function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Sirtuins: critical regulators at the crossroads between cancer and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The Sirtuin family: therapeutic targets to treat diseases of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Pharmacological inhibition of histone deacetylases for the treatment of cancer, neurodegenerative disorders and inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Vorinostat in solid and hematologic malignancies

21 January 2018

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Novel histone deacetylase inhibitors in clinical trials as anti-cancer agents

21 January 2018

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Recent advances in histone deacetylase targeted cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone-deacetylase inhibitors: novel drugs for the treatment of cancer

21 January 2018

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https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Clinical development of histone deacetylase inhibitors as anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Review article: the role of butyrate on colonic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Butyrate modulates oxidative stress in the colonic mucosa of healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The short chain fatty acid butyrate induces promoter demethylation and reactivation of RARbeta2 in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Molecular changes in the expression of human colonic nutrient transporters during the transition from normality to malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Na(+)/monocarboxylate transport (SMCT) protein expression correlates with survival in colon cancer: molecular characterization of SMCT

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Short chain fatty acid distributions of enema samples from a sigmoidoscopy population: an association of high acetate and low butyrate ratios with adenomatous polyps and colon cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Targeting histone deacetylase in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

New clinical developments in histone deacetylase inhibitors for epigenetic therapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Discovery and development of SAHA as an anticancer agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Early phase II trial of oral vorinostat in relapsed or refractory breast, colorectal, or non-small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Vorinostat, a histone deacetylase inhibitor, combined with pelvic palliative radiotherapy for gastrointestinal carcinoma: the Pelvic Radiation and Vorinostat (PRAVO) phase 1 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Gastrointestinal toxicity of vorinostat: reanalysis of phase 1 study results with emphasis on dose-volume effects of pelvic radiotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

CRA-024781: a novel synthetic inhibitor of histone deacetylase enzymes with antitumor activity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A phase 1 pharmacokinetic and pharmacodynamic study of the histone deacetylase inhibitor belinostat in patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Development of the pan-DAC inhibitor panobinostat (LBH589): successes and challenges

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

High efficacy of panobinostat towards human gastrointestinal stromal tumors in a xenograft mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

The dual EGFR/HER2 inhibitor lapatinib synergistically enhances the antitumor activity of the histone deacetylase inhibitor panobinostat in colorectal cancer models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

FR901228, a potent antitumor antibiotic, is a novel histone deacetylase inhibitor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone deacetylases and cancer: causes and therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A synthetic inhibitor of histone deacetylase, MS-27-275, with marked in vivo antitumor activity against human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Synthesis and histone deacetylase inhibitory activity of new benzamide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A phase I and pharmacokinetic study of the oral histone deacetylase inhibitor, MS-275, in patients with refractory solid tumors and lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Multicenter phase II trial of the histone deacetylase inhibitor pyridylmethyl-N-{4-[(2-aminophenyl)-carbamoyl]-benzyl}-carbamate in pretreated metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Chronic oral administration of CI-994: a phase 1 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Phase I study of oral CI-994 in combination with gemcitabine in treatment of patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

A phase I study of the oral combination of CI-994, a putative histone deacetylase inhibitor, and capecitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Phase I study of oral CI-994 in combination with carboplatin and paclitaxel in the treatment of patients with advanced solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Effect of glutathione-S-transferase polymorphisms on the cancer preventive potential of isothiocyanates: an epidemiological perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms and gastric cancer risk: a prospective study of men in Shanghai, China

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone acetyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

Histone deacetylase inhibitors: a chemical genetics approach to understanding cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FABBS%2FGMR113

21 January 2018

Identifiers

DOI

10.1093/ABBS/GMR113

1 reference

26 August 2017

1 reference