Hypermethylation in bladder cancer: biological pathways and translational applications (Q37978544)

26 August 2017

title

Hypermethylation in bladder cancer: biological pathways and translational applications (English)

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26 August 2017

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Marta Sánchez-Carbayo

series ordinal

1

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26 August 2017

publication date

25 January 2012

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26 August 2017

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26 August 2017

volume

33

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26 August 2017

issue

2

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26 August 2017

page(s)

347-361

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Cancer epigenetics comes of age

26 August 2017

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The power and the promise of DNA methylation markers

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The epigenomics of cancer

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Epigenetic gene silencing in cancer: the DNA hypermethylome

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DNA methylation landscapes: provocative insights from epigenomics

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21 January 2018

Epigenetics in cancer

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Human DNA methylomes at base resolution show widespread epigenomic differences

21 January 2018

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Developmental programming of CpG island methylation profiles in the human genome

21 January 2018

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Insulin gene expression is regulated by DNA methylation

21 January 2018

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CpG islands influence chromatin structure via the CpG-binding protein Cfp1.

21 January 2018

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The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

21 January 2018

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Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts

21 January 2018

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Gene body-specific methylation on the active X chromosome

21 January 2018

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Role for DNA methylation in the control of cell type specific maspin expression

21 January 2018

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Epigenetic control of mouse Oct-4 gene expression in embryonic stem cells and trophoblast stem cells

21 January 2018

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

21 January 2018

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The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells

21 January 2018

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Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells

21 January 2018

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21 January 2018

Global cancer statistics

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Use of high-throughput DNA microarrays to identify biomarkers for bladder cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Molecular alterations associated with bladder cancer progression

21 January 2018

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https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Applications of array technology: identification of molecular targets in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Mechanisms of Disease: genetic and epigenetic alterations that drive bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

The role of deoxyribonucleic acid methylation in development, diagnosis, and prognosis of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Methylation-based biomarkers for early detection of urological cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Epigenetics in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Epigenetic markers as promising prognosticators for bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Epigenetic biomarkers in urothelial bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Interest of methylated genes as biomarkers in urothelial cell carcinomas of the urinary tract

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Mutation in TET2 in myeloid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

MS-qFRET: a quantum dot-based method for analysis of DNA methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Sensitive digital quantification of DNA methylation in clinical samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Quantitative evaluation of DNA methylation by optimization of a differential-high resolution melt analysis protocol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Carcinogen exposure and gene promoter hypermethylation in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Identification of DNA hypermethylation of SOX9 in association with bladder cancer progression using CpG microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

DNA methylation profiles delineate etiologic heterogeneity and clinically important subgroups of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Unique DNA methylation patterns distinguish noninvasive and invasive urothelial cancers and establish an epigenetic field defect in premalignant tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Identification of methylated genes associated with aggressive bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Association of secondhand smoke exposures with DNA methylation in bladder carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

A novel epigenetic phenotype associated with the most aggressive pathway of bladder tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Custom-designed MLPA using multiple short synthetic probes: application to methylation analysis of five promoter CpG islands in tumor and urine specimens from patients with bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Multiplexed methylation profiles of tumor suppressor genes in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

The retinoblastoma protein and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Genetic alterations of p16INK4a and p14ARF genes in human bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Detection of bladder cancer in urine by a tumor suppressor gene hypermethylation panel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Evidence for the early onset of aberrant promoter methylation in urothelial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Detection of methylated apoptosis-associated genes in urine sediments of bladder cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

p16INK4a and p14ARF methylation as a potential biomarker for human bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Promoter hypermethylation in tumour suppressor genes shows association with stage, grade and invasiveness of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

BAMBI gene is epigenetically silenced in subset of high-grade bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Promoter hypermethylation in tumour suppressor genes and response to interleukin-2 treatment in bladder cancer: a pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Promoter hypermethylation identifies progression risk in bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Multiple mechanisms downregulate CDKN1C in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Comprehensive analysis of CDKN2A status in microdissected urothelial cell carcinoma reveals potential haploinsufficiency, a high frequency of homozygous co-deletion and associations with clinical phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

PAX6 methylation and ectopic expression in human tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Chfr defines a mitotic stress checkpoint that delays entry into metaphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Prognostic relevance of methylation markers in patients with non-muscle invasive bladder carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Regularly methylated novel pro-apoptotic genes associated with recurrence in transitional cell carcinoma of the bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Comparative promoter methylation analysis of p53 target genes in urogenital cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

RUNX3 methylation reveals that bladder tumors are older in patients with a history of smoking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Quantitative methylation analysis of BCL2, hTERT, and DAPK promoters in urine sediment for the detection of non-muscle-invasive urothelial carcinoma of the bladder: a prospective, two-center validation study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Identification of a novel Ras-regulated proapoptotic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

DNA methylation patterns in bladder cancer and washing cell sediments: a perspective for tumor recurrence detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Cadherin cell adhesion receptors as a morphogenetic regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Changing views of the role of matrix metalloproteinases in metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Form and function: the laminin family of heterotrimers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

CpG hypermethylation of promoter region and inactivation of E-cadherin gene in human bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Hypermethylation of an E-cadherin (CDH1) promoter region in high grade transitional cell carcinoma of the bladder comprising carcinoma in situ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Low frequency of epigenetic events in urothelial tumors in young patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Distinct DNA methylation epigenotypes in bladder cancer from different Chinese sub-populations and its implication in cancer detection using voided urine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Three epigenetic biomarkers, GDF15, TMEFF2, and VIM, accurately predict bladder cancer from DNA-based analyses of urine samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Differential protein expression profiling by iTRAQ-two-dimensional LC-MS/MS of human bladder cancer EJ138 cells transfected with the metastasis suppressor KiSS-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

KISS1 methylation and expression as tumor stratification biomarkers and clinical outcome prognosticators for bladder cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Epigenetic inactivation of Wnt inhibitory factor-1 plays an important role in bladder cancer through aberrant canonical Wnt/beta-catenin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Hypermethylated SFRP1, but none of other nine genes "informative" for western countries, is valuable for bladder cancer detection in Mainland China.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Epigenetic regulation of Wnt signaling pathway in urological cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

RUNX3 inactivation by point mutations and aberrant DNA methylation in bladder tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

A novel set of DNA methylation markers in urine sediments for sensitive/specific detection of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Discovery of myopodin methylation in bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Relationship of SNCG, S100A4, S100A9 and LCN2 gene expression and DNA methylation in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Identification of PMF1 methylation in association with bladder cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Aberrant methylation of RARbeta2 and APC genes in voided urine as molecular markers for early detection of bilharzial and nonbilharzial bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Integrated genetic and epigenetic analysis of bladder cancer reveals an additive diagnostic value of FGFR3 mutations and hypermethylation events

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Hypermethylation of tumor-suppressor gene CpG islands in small-cell carcinoma of the urinary bladder.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

A comparison of the performance of microsatellite and methylation urine analysis for predicting the recurrence of urothelial cell carcinoma, and definition of a set of markers by Bayesian network analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Identification and validation of the methylated TWIST1 and NID2 genes through real-time methylation-specific polymerase chain reaction assays for the noninvasive detection of primary bladder cancer in urine samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Copy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Detection of bladder cancer using novel DNA methylation biomarkers in urine sediments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-011-0310-2

DNMT3A Mutations in Acute Myeloid Leukemia

21 January 2018

1 reference

12 December 2020

Chromosomal Instability and Tumors Promoted by DNA Hypomethylation

1 reference

12 December 2020

Methylation profiling of urothelial carcinoma in bladder biopsy and urine

1 reference

12 December 2020

Protein expression and gene promoter hypermethylation of CD99 in transitional cell carcinoma of urinary bladder

1 reference

12 December 2020

Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma.

1 reference

12 December 2020

Assessing the use of p16(INK4a) promoter gene methylation in serum for detection of bladder cancer

1 reference

12 December 2020

Increase sensitivity in detecting superficial, low grade bladder cancer by combination analysis of hypermethylation of E-cadherin, p16, p14, RASSF1A genes in urine

1 reference

12 December 2020

Epigenetic Inactivation of SFRP Genes and TP53 Alteration Act Jointly as Markers of Invasive Bladder Cancer

1 reference

12 December 2020

Hypermethylation at 9q32-33 tumour suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer

1 reference

12 December 2020

Hypermethylation of multiple genes in tumor tissues and voided urine in urinary bladder cancer patients

1 reference

12 December 2020

Genetic and epigenetic biomarkers for early detection, therapeutic effectiveness and relapse monitoring in bladder cancer

1 reference

12 December 2020

CpG hypermethylation of collagen type I alpha 2 contributes to proliferation and migration activity of human bladder cancer.

1 reference

12 December 2020

Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features

1 reference

12 December 2020

Cell division is required for de novo methylation of CpG islands in bladder cancer cells

1 reference

12 December 2020

The association of death-associated protein kinase hypermethylation with early recurrence in superficial bladder cancers.

1 reference

12 December 2020

DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain

1 reference

12 December 2020

A methylation assay for the detection of non-muscle-invasive bladder cancer (NMIBC) recurrences in voided urine.

1 reference

12 December 2020

Prevalence of aberrant methylation of p14ARF over p16INK4a in some human primary tumors

1 reference

12 December 2020

Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase

1 reference

12 December 2020

Methylational urinalysis: a prospective study of bladder cancer patients and age stratified benign controls

1 reference

12 December 2020

Alteration of the MDM2-p73-P14ARF pathway related to tumour progression during urinary bladder carcinogenesis

1 reference

12 December 2020

Cancer epigenetics is no Mickey Mouse

1 reference

12 December 2020

Hypermethylation of E-cadherin, p16, p14, and RASSF1A genes in pathologically normal urothelium predict bladder recurrence of bladder cancer after transurethral resection

1 reference

12 December 2020

CpG hypermethylation of cellular retinol-binding protein 1 contributes to cell proliferation and migration in bladder cancer

1 reference

12 December 2020

Myopodin Methylation is Associated With Clinical Outcome in Patients With T1G3 Bladder Cancer

1 reference

12 December 2020

A DNA methylation fingerprint of 1628 human samples

1 reference

12 December 2020

High frequency of promoter methylation of the 14-3-3 sigma and CAGE-1 genes, but lack of hypermethylation of the caveolin-1 gene, in primary adenocarcinomas and signet ring cell carcinomas of the urinary bladder

1 reference

12 December 2020

Evaluation of the methylation status of tumour suppressor genes for predicting bacillus Calmette-Guérin response in patients with T1G3 high-risk bladder tumours

1 reference

12 December 2020

Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas.

1 reference

12 December 2020

Increased DNA methyltransferase 1 protein expression in human transitional cell carcinoma of the bladder

1 reference

12 December 2020

Methylation of the TPEF- and PAX6-promoters is increased in early bladder cancer and in normal mucosa adjacent to pTa tumours

1 reference

12 December 2020

Molecular and Immunohistochemical Analysis of the Prognostic Value of Cell-Cycle Regulators in Urothelial Neoplasms of the Bladder

1 reference

12 December 2020

DNA methylation and the mechanisms of CDKN2A inactivation in transitional cell carcinoma of the urinary bladder

1 reference

12 December 2020

Genome-scale DNA methylation maps of pluripotent and differentiated cells

1 reference

12 December 2020

10.1007/S13277-011-0310-2

Identifiers

DOI

1 reference

release_bkuwwpufyndwdmuxlvycgdzcte

26 August 2017

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https://api.fatcat.wiki/v0/release/bkuwwpufyndwdmuxlvycgdzcte

24 November 2022

mapped directly with Wikidata item

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