Energy metabolism and proliferation in pancreatic carcinogenesis (Q37994998)

26 August 2017

Energy metabolism and proliferation in pancreatic carcinogenesis (English)

1 reference

26 August 2017

1 reference

4

Mert Erkan

1 reference

26 August 2017

Ivonne Regel

1

1 reference

26 August 2017

Bo Kong

2

1 reference

26 August 2017

Susanne Raulefs

3

1 reference

26 August 2017

Christoph W Michalski

5

1 reference

26 August 2017

Mark Hartel

6

1 reference

26 August 2017

Jörg Kleeff

7

1 reference

26 August 2017

language of work or name

English

0 references

publication date

20 March 2012

1 reference

Langenbeck's Archives of Surgery

26 August 2017

1 reference

26 August 2017

397

1 reference

26 August 2017

4

1 reference

26 August 2017

507-512

1 reference

https://scigraph.springernature.com/pub.10.1007/s00423-012-0933-9

26 August 2017

0 references

cites work

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

21 January 2018

Cancer statistics, 2012

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Aerobically derived lactate stimulates revascularization and tissue repair via redox mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

The control of the metabolic switch in cancers by oncogenes and tumor suppressor genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Proteomic analysis reveals Warburg effect and anomalous metabolism of glutamine in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Effect of low glutamine/glucose on hypoxia-induced elevation of hypoxia-inducible factor-1alpha in human pancreatic cancer MiaPaCa-2 and human prostatic cancer DU-145 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Otto Warburg's contributions to current concepts of cancer metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Inborn and acquired metabolic defects in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Genetics and biology of pancreatic ductal adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Pancreatic ductal adenocarcinoma and transcription factors: role of c-Myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Reflecting on 25 years with MYC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

MYC-induced cancer cell energy metabolism and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Decision making by p53: life, death and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Cancer risks in LKB1 germline mutation carriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Genome profiling of pancreatic adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

LKB1-dependent signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Tissue- and site-specific DNA recombination in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Insulin-promoter-factor 1 is required for pancreas development in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

The bHLH protein PTF1-p48 is essential for the formation of the exocrine and the correct spatial organization of the endocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

STK11/LKB1 Peutz-Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

LKB1 haploinsufficiency cooperates with Kras to promote pancreatic cancer through suppression of p21-dependent growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Conditional inactivation of Myc impairs development of the exocrine pancreas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Pancreatic tumor pathogenesis reflects the causative genetic lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Pancreatic Inactivation of c-Myc Decreases Acinar Mass and Transdifferentiates Acinar Cells Into Adipocytes in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00423-012-0933-9

Ras-dependent carbon metabolism and transformation in mouse fibroblasts

21 January 2018

1 reference

12 December 2020

Origin of pancreatic ductal adenocarcinoma from atypical flat lesions: a comparative study in transgenic mice and human tissues.

1 reference

12 December 2020

The LKB1 tumor suppressor kinase in human disease

1 reference

12 December 2020

PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum

1 reference

12 December 2020

p16 and K-ras gene mutations in the intraductal precursors of human pancreatic adenocarcinoma

1 reference

12 December 2020

Pancreatic adenocarcinomas frequently show p53 gene mutations.

1 reference

12 December 2020

K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions.

1 reference

12 December 2020

The fundamental role of the p53 pathway in tumor metabolism and its implication in tumor therapy

1 reference

12 December 2020

c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: incidence, mechanisms, and clinical significance

1 reference

12 December 2020

10.1007/S00423-012-0933-9

Identifiers

DOI

1 reference

26 August 2017

1 reference