Detection of EPO gene doping in blood (Q38003108)

26 August 2017

Detection of EPO gene doping in blood (English)

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26 August 2017

Elmo W I Neuberger

1

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26 August 2017

Magdalena Jurkiewicz

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2

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26 August 2017

Dirk A Moser

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3

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26 August 2017

Perikles Simon

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4

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26 August 2017

17 April 2012

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Drug Testing and Analysis

26 August 2017

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26 August 2017

4

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26 August 2017

11

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26 August 2017

859-869

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Ex vivo gene transfer and correction for cell-based therapies

26 August 2017

1 reference

7 January 2021

State-of-the-art gene-based therapies: the road ahead

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7 January 2021

Progress and problems with the use of viral vectors for gene therapy

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7 January 2021

Progress toward a nonviral gene therapy protocol for the treatment of anemia

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7 January 2021

Gene therapy for human genetic disease?

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7 January 2021

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

1 reference

7 January 2021

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

7 January 2021

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils

1 reference

7 January 2021

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

1 reference

7 January 2021

Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia

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7 January 2021

Long-term safety of intramuscular gene transfer of non-viral FGF1 for peripheral artery disease

1 reference

7 January 2021

CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

1 reference

7 January 2021

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

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7 January 2021

How close are we to gene doping?

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7 January 2021

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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7 January 2021

Gene therapy. Blood test flags agent in death of Penn subject

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7 January 2021

What are the consequences of the fourth case?

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7 January 2021

Would you dope? A general population test of the Goldman dilemma.

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7 January 2021

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7 January 2021

Guidelines for human gene nomenclature

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7 January 2021

Gene doping: the hype and the reality.

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7 January 2021

Gene doping: of mice and men.

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7 January 2021

Growth hormone, IGF-I and insulin and their abuse in sport.

1 reference

7 January 2021

Viral expression of insulin-like growth factor-I enhances muscle hypertrophy in resistance-trained rats.

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7 January 2021

Myostatin mutation associated with gross muscle hypertrophy in a child

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7 January 2021

The myostatin gene: physiology and pharmacological relevance

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7 January 2021

Inducible adeno-associated virus vectors promote functional angiogenesis in adult organisms via regulated vascular endothelial growth factor expression.

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7 January 2021

Erythropoietin: structure, control of production, and function

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7 January 2021

Regional assignment of the erythropoietin gene to human chromosome region 7pter----q22.

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7 January 2021

Erythropoiesis stimulating agents and techniques: a challenge for doping analysts

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7 January 2021

The molecular mechanism of erythropoietin action

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7 January 2021

Erythropoiesis-stimulating agents and other methods to enhance oxygen transport

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7 January 2021

Persistent erythropoiesis by myoblast transfer of erythropoietin cDNA.

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7 January 2021

Stable delivery of physiologic levels of recombinant erythropoietin to the systemic circulation by intramuscular injection of replication-defective adenovirus

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7 January 2021

Immune responses to transgene-encoded proteins limit the stability of gene expression after injection of replication-defective adenovirus vectors

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7 January 2021

Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-defective adenoviral vector

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7 January 2021

Efficient and stable adeno-associated virus-mediated transduction in the skeletal muscle of adult immunocompetent mice

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7 January 2021

Erythropoietin gene therapy leads to autoimmune anemia in macaques

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7 January 2021

Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer.

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7 January 2021

Lentivirus administration to rat muscle provides efficient sustained expression of erythropoietin.

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7 January 2021

Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

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7 January 2021

Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle.

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7 January 2021

Humoral immunity to adeno-associated virus type 2 vectors following administration to murine and nonhuman primate muscle

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7 January 2021

Autoimmune anemia in macaques following erythropoietin gene therapy

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7 January 2021

Longevity of rAAV vector and plasmid DNA in blood after intramuscular injection in nonhuman primates: implications for gene doping

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7 January 2021

Distinct immune responses to transgene products from rAAV1 and rAAV8 vectors

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7 January 2021

Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus

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7 January 2021

Control of erythropoietin secretion by doxycycline or mifepristone in mice bearing polymer-encapsulated engineered cells

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7 January 2021

Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy

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7 January 2021

Myoglobin O2 desaturation during exercise. Evidence of limited O2 transport

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7 January 2021

Physiological activation of hypoxia inducible factor-1 in human skeletal muscle

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7 January 2021

Immune responses to gene product of inducible promoters

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7 January 2021

Adeno-associated virus vector genomes persist as episomal chromatin in primate muscle

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7 January 2021

Progress and prospects: the design and production of plasmid vectors.

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7 January 2021

Gene electro-transfer of an improved erythropoietin plasmid in mice and non-human primates

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7 January 2021

Gene therapy progress and prospects: hydrodynamic gene delivery

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7 January 2021

A robust system for production of minicircle DNA vectors

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7 January 2021

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

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7 January 2021

Gene therapy for long-term expression of erythropoietin in rats

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7 January 2021

Sustained delivery of erythropoietin in mice by genetically modified skin fibroblasts

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7 January 2021

Development of approaches to improve cell survival in myoblast transfer therapy

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7 January 2021

A role for natural killer cells in the rapid death of cultured donor myoblasts after transplantation.

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7 January 2021

Human erythropoietin gene therapy for patients with chronic renal failure

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7 January 2021

SEMIPERMEABLE MICROCAPSULES

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7 January 2021

Human-compatible collagen matrix for prolonged and reversible systemic delivery of erythropoietin in mice from gene-modified marrow stromal cells

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7 January 2021

Long-term expression of erythropoietin from myoblasts immobilized in biocompatible and neovascularized microcapsules

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7 January 2021

Causes of limited survival of microencapsulated pancreatic islet grafts.

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7 January 2021

Progress technology in microencapsulation methods for cell therapy

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7 January 2021

The quest for clean competition in sports: are the testers catching the dopers?

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7 January 2021

“Genetic Doping” with erythropoietin cDNA in primate muscle is detectable

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7 January 2021

Biosafety in ex vivo gene therapy and conditional ablation of lentivirally transduced hepatocytes in nonhuman primates

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7 January 2021

Ethics. Gene doping and sport

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7 January 2021

The peripheral-blood transcriptome: new insights into disease and risk assessment

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7 January 2021

Multifarious microarray-based gene expression patterns in response to exercise

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7 January 2021

Detection of growth hormone doping by gene expression profiling of peripheral blood.

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7 January 2021

Twenty-five years of quantitative PCR for gene expression analysis.

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7 January 2021

Modification of gene expression: Help to detect doping with erythropoiesis-stimulating agents

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7 January 2021

The athlete biological passport

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7 January 2021

Gene-expression variation within and among human populations

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7 January 2021

Variation in gene expression profiles of peripheral blood mononuclear cells from healthy volunteers.

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7 January 2021

Exertional heat injury and gene expression changes: a DNA microarray analysis study

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7 January 2021

Exercise affects the gene expression profiles of human white blood cells

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7 January 2021

Simultaneous gene expression signature of heart and peripheral blood mononuclear cells in astemizole-treated rats

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7 January 2021

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

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7 January 2021

Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents.

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7 January 2021

Effects of storage, RNA extraction, genechip type, and donor sex on gene expression profiling of human whole blood.

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7 January 2021

Principle considerations for the use of transcriptomics in doping research.

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7 January 2021

MicroRNAs: genomics, biogenesis, mechanism, and function

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7 January 2021

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

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7 January 2021

Analysis of circulating microRNA: preanalytical and analytical challenges.

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7 January 2021

Bayesian detection of abnormal hematological values to introduce a no-start rule for heterogeneous populations of athletes.

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7 January 2021

Prevalence of blood doping in samples collected from elite track and field athletes

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7 January 2021

Current markers of the Athlete Blood Passport do not flag microdose EPO doping.

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7 January 2021

Gene doping detection: evaluation of approach for direct detection of gene transfer using erythropoietin as a model system

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7 January 2021

Simultaneous detection of transgenic DNA by surface plasmon resonance imaging with potential application to gene doping detection.

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7 January 2021

Surface plasmon resonance imaging

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7 January 2021

Direct and long-term detection of gene doping in conventional blood samples.

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7 January 2021

Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy

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7 January 2021

Phase 1 trial of FVIII gene transfer for severe hemophilia A using a retroviral construct administered by peripheral intravenous infusion

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7 January 2021

Mass spectrometric detection of siRNA in plasma samples for doping control purposes

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7 January 2021

Monitoring gene therapy by external imaging of mRNA: pilot study on murine erythropoietin.

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7 January 2021

Immune responses to gene therapy vectors: influence on vector function and effector mechanisms

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7 January 2021

Immune responses to adenovirus and adeno-associated virus in humans.

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7 January 2021

Points to consider for ethics committees in human gene therapy trials

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7 January 2021

Capsid antigen presentation flags human hepatocytes for destruction after transduction by adeno-associated viral vectors

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7 January 2021

Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscle

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7 January 2021

Development of a sensitive assay for detection of replication-competent recombinant lentivirus in large-scale HIV-based vector preparations

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7 January 2021

Reducing the risk of adeno-associated virus (AAV) vector mobilization with AAV type 5 vectors

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7 January 2021

Frequency and spectrum of genomic integration of recombinant adeno-associated virus serotype 8 vector in neonatal mouse liver

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7 January 2021

No evidence for germ-line transmission following prenatal and early postnatal AAV-mediated gene delivery.

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7 January 2021

Transfection of oocytes and other types of ovarian cells in rabbits after direct injection into uterine arteries of adenoviruses and plasmid/liposomes.

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7 January 2021

Adenoviral vectors for gene replacement therapy

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7 January 2021

Chromosomal integration of adenoviral vector DNA in vivo.

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7 January 2021

Toolbox for retrovectorologists

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7 January 2021

Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector

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7 January 2021

Identifiers

DOI

10.1002/DTA.1347

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26 August 2017

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