Vitamin B12 transport from food to the body's cells--a sophisticated, multistep pathway (Q38006649)

26 August 2017

Vitamin B12 transport from food to the body's cells--a sophisticated, multistep pathway (English)

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26 August 2017

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5

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26 August 2017

Marianne J Nielsen

1

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26 August 2017

Mie R Rasmussen

series ordinal

2

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26 August 2017

Christian B F Andersen

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3

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26 August 2017

Ebba Nexø

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4

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26 August 2017

language of work or name

English

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publication date

1 May 2012

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Nature Reviews Gastroenterology & Hepatology

26 August 2017

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26 August 2017

9

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26 August 2017

345-354

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26 August 2017

6

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https://scigraph.springernature.com/pub.10.1038/nrgastro.2012.76

26 August 2017

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cites work

Review of the magnitude of folate and vitamin B12 deficiencies worldwide

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

An update on cobalamin deficiency in adults.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Vitamin B12, folic acid, and the nervous system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Binding site revealed of nature's most beautiful cofactor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

31 March 2020

Crystalline Vitamin B12.

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Vitamin B12, A Cobalt Complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Purification of Anti-pernicious Anæmia Factors from Liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Some Observations on the Crystal Structure of a Chlorine-substituted Vitamin B12

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Isolation of Methylcobalamin from Natural Source Material

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Structure of vitamin B12.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Microbial production of vitamin B12

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Crystal structure of human intrinsic factor: cobalamin complex at 2.6-A resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Structural basis for mammalian vitamin B12 transport by transcobalamin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Characterization of an epithelial approximately 460-kDa protein that facilitates endocytosis of intrinsic factor-vitamin B12 and binds receptor-associated protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

How a protein binds B12: A 3.0 A X-ray structure of B12-binding domains of methionine synthase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Intrinsic factor antibody in serum from patients with pernicious anaemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Hereditary juvenile cobalamin deficiency caused by mutations in the intrinsic factor gene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

THE ETIOLOGY OF PERNICIOUS AND RELATED MACROCYTIC ANEMIAS

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Nonsense mutations in human transcobalamin II deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification of two mutant alleles of transcobalamin II in an affected family

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Transcobalamin deficiency due to activation of an intra exonic cryptic splice site

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Transcobalamin deficiency caused by compound heterozygosity for two novel mutations in the TCN2 gene: a study of two affected siblings, their brother, and their parents

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Congenital transcobalamin II deficiency due to errors in RNA editing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Mouse transcobalamin has features resembling both human transcobalamin and haptocorrin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

31 March 2020

Haptocorrin in humans

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification and quantitation of cobalamin and cobalamin analogues in human feces

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

A new principle for measurement of cobalamin and corrinoids, used for studies of cobalamin analogs on serum haptocorrin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Ins and outs of cellular cobalamin transport

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Advances in the understanding of cobalamin assimilation and metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Indicators for assessing folate and vitamin B12 status and for monitoring the efficacy of intervention strategies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Facts and recommendations about total homocysteine determinations: an expert opinion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Sensitivity of serum methylmalonic acid and total homocysteine determinations for diagnosing cobalamin and folate deficiencies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Effect of proteolytic enzymes on the binding of cobalamin to R protein and intrinsic factor. In vitro evidence that a failure to partially degrade R protein is responsible for cobalamin malabsorption in pancreatic insufficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Characterization of a 280-kD protein restricted to the coated pits of the renal brush border and the epithelial cells of the yolk sac. Teratogenic effect of the specific monoclonal antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Molecular Dissection of the Intrinsic Factor-Vitamin B12Receptor, Cubilin, Discloses Regions Important for Membrane Association and Ligand Binding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Structural basis for receptor recognition of vitamin-B(12)-intrinsic factor complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Cubilin- and megalin-mediated uptake of albumin in cultured proximal tubule cells of opossum kidney.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Luminal expression of cubilin is impaired in Imerslund-Grasbeck syndrome with compound AMN mutations in intron 3 and exon 7.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

A patient with cubilin deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Selective vitamin B12 malabsorption and proteinuria in young people. A syndrome.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Mutations in CUBN, encoding the intrinsic factor-vitamin B12 receptor, cubilin, cause hereditary megaloblastic anaemia 1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Canine Imerslund-Gräsbeck syndrome maps to a region orthologous to HSA14q.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Defect in vitamin B12 release from lysosomes: newly described inborn error of vitamin B12 metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Genetic disorders of vitamin B12 metabolism: eight complementation groups – eight genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The tinker, tailor, soldier in intracellular B12 trafficking

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Processing of alkylcobalamins in mammalian cells: A role for the MMACHC (cblC) gene product

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Decyanation of vitamin B12 by a trafficking chaperone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

A human vitamin B12 trafficking protein uses glutathione transferase activity for processing alkylcobalamins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Gene identification for the cblD defect of vitamin B12 metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Clinical and molecular heterogeneity in patients with the cblD inborn error of cobalamin metabolism.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The cblD defect causes either isolated or combined deficiency of methylcobalamin and adenosylcobalamin synthesis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Cobalamin transport proteins and their cell-surface receptors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Investigation of the ABC transporter MRP1 in selected patients with presumed defects in vitamin B12 absorption.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Membrane expression and interactions of human transcobalamin II receptor.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Characterization of the particulate and soluble acceptor for transcobalamin II from human placenta and rabbit liver

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Expression of CD320 in human B cells in addition to follicular dendritic cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Characterization of a Novel Gene in the Extended MHC Region of Mouse, NG29/Cd320, a Homolog of the Human CD320.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Soluble transcobalamin receptor, sCD320, is present in human serum and relates to serum cobalamin - establishment and validation of an ELISA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The dynamics of cobalamin utilization in L-1210 mouse leukemia cells: a model of cellular cobalamin metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Binding and Uptake of Transcobalamin II by Human Fibroblasts

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Positive newborn screen for methylmalonic aciduria identifies the first mutation in TCblR/CD320, the gene for cellular uptake of transcobalamin-bound vitamin B(12)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Diversity in rat tissue accumulation of vitamin B12 supports a distinct role for the kidney in vitamin B12 homeostasis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Megalin-mediated endocytosis of transcobalamin-vitamin-B12 complexes suggests a role of the receptor in vitamin-B12 homeostasis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The kidney in vitamin B12 and folate homeostasis: characterization of receptors for tubular uptake of vitamins and carrier proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Vitamin B12 in the rat kidney. Evidence for an association with lysosomes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Megalin acts in concert with cubilin to mediate endocytosis of high density lipoproteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Megalin knockout mice as an animal model of low molecular weight proteinuria.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Is it time for vitamin B-12 fortification? What are the questions?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

The vitamin B12 absorption test, CobaSorb, identifies patients not requiring vitamin B12 injection therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Human intrinsic factor expressed in the plant Arabidopsis thaliana

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Vitamin B12 in drug delivery: breaking through the barriers to a B12 bioconjugate pharmaceutical

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Targeted delivery of saporin toxin by monoclonal antibody to the transcobalamin receptor, TCblR/CD320.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRGASTRO.2012.76

Cobalamin release from intrinsic factor and transfer to transcobalamin II within the rat enterocyte

31 March 2020

1 reference

12 December 2020

Defective brush-border expression of intrinsic factor-cobalamin receptor in canine inherited intestinal cobalamin malabsorption

1 reference

12 December 2020

Major vault protein LRP-related multidrug resistance

1 reference

12 December 2020

The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region

1 reference

12 December 2020

Effective treatment of cobalamin deficiency with oral cobalamin

1 reference

12 December 2020

Diagnosis and treatment of vitamin B12 deficiency--an update

1 reference

12 December 2020

Purification, properties, and immunochemical localization of a receptor for intrinsic factor-cobalamin complex in the rat kidney

1 reference

12 December 2020

Cellular fluxes of vitamin B12

1 reference

12 December 2020

Intrinsic factor studies II. The effect of gastric juice on the urinary excretion of radioactivity after the oral administration of radioactive vitamin B12

1 reference

12 December 2020

Characterization of the receptor for transcobalamin II isolated from human placenta

1 reference

12 December 2020

Glycosylation is not required for ligand or receptor binding by expressed rat intrinsic factor

1 reference

12 December 2020

Vitamin B12-binders in human body fluids. I. Antigenic and physico-chemical characteristics

1 reference

12 December 2020

The Carriers of Native Vitamin B12 in Normal Human Serum

1 reference

12 December 2020

Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin

1 reference

12 December 2020

Expression of transcobalamin II receptors by human leukemia K562 and HL-60 cells

1 reference

12 December 2020

Idiopathic chronic megaloblastic anemia in children

1 reference

12 December 2020

Genetic evidence of an accessory activity required specifically for cubilin brush-border expression and intrinsic factor-cobalamin absorption

1 reference

12 December 2020

Human plasma R-type vitamin B12-binding proteins. II. The role of transcobalamin I, transcobalamin III, and the normal granulocyte vitamin B12-binding protein in the plasma transport of vitamin B12

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRGASTRO.2012.76

1 reference

Dimensions Publication ID

26 August 2017

0 references

1 reference