AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2 (Q24296494)

receptor-mediated endocytosis

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Linton M Traub

4

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author name string

Gitte Albinus Pedersen

1

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Souvik Chakraborty

2

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Amie L Steinhauser

3

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Mette Madsen

Genome analysis of the platypus reveals unique signatures of evolution

5

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language of work or name

English

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publication date

May 2010

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published in

Traffic

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volume

11

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issue

5

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page(s)

706-20

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cites work

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The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH

19 March 2017

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Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein

19 March 2017

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The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless

19 March 2017

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The Adaptor Protein ARH Escorts Megalin to and through Endosomes

19 March 2017

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The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery

19 March 2017

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Disabled-2 exhibits the properties of a cargo-selective endocytic clathrin adaptor

19 March 2017

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ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2

19 March 2017

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Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport

19 March 2017

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Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3)

19 March 2017

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Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

19 March 2017

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Cubilin is an albumin binding protein important for renal tubular albumin reabsorption

19 March 2017

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Cytosolic adaptor protein Dab2 is an intracellular ligand of endocytic receptor gp600/megalin

19 March 2017

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The intrinsic factor-vitamin B12 receptor and target of teratogenic antibodies is a megalin-binding peripheral membrane protein with homology to developmental proteins

19 March 2017

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The targeting of Lamp1 to lysosomes is dependent on the spacing of its cytoplasmic tail tyrosine sorting motif relative to the membrane

19 March 2017

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A structural explanation for the binding of endocytic dileucine motifs by the AP2 complex

19 March 2017

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Molecular architecture and functional model of the endocytic AP2 complex

19 March 2017

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A structural explanation for the recognition of tyrosine-based endocytotic signals

19 March 2017

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Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein

19 March 2017

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Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia

19 March 2017

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Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein

19 March 2017

1 reference

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Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2

19 March 2017

1 reference

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Interaction of tyrosine-based sorting signals with clathrin-associated proteins

19 March 2017

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NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor

19 March 2017

1 reference

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Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules

19 March 2017

1 reference

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

19 March 2017

1 reference

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Adaptable adaptors for coated vesicles

7 April 2017

1 reference

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Tickets to ride: selecting cargo for clathrin-regulated internalization.

7 April 2017

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Integrating molecular and network biology to decode endocytosis

27 September 2017

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Global analysis of hematopoietic and vascular endothelial gene expression by tissue specific microarray profiling in zebrafish

27 September 2017

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Endocytic adaptors: recruiters, coordinators and regulators

27 September 2017

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A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors

27 September 2017

1 reference

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Modulation of lipoprotein receptor functions by intracellular adaptor proteins

27 September 2017

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Epsin 1 is a polyubiquitin-selective clathrin-associated sorting protein.

27 September 2017

1 reference

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Contribution of cubilin and amnionless to processing and membrane targeting of cubilin-amnionless complex

27 September 2017

1 reference

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Mutually dependent localization of megalin and Dab2 in the renal proximal tubule.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964065

Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964065

Biologic characteristics of a continuous kidney cell line derived from the African green monkey.

27 September 2017

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Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia

27 September 2017

1 reference

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The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964065

Megalin knockout mice as an animal model of low molecular weight proteinuria.

27 September 2017

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The intrinsic factor-vitamin B12 receptor, cubilin, is a high-affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2964065

Distinct saturable pathways for the endocytosis of different tyrosine motifs

27 September 2017

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The human intrinsic factor-vitamin B12 receptor, cubilin: molecular characterization and chromosomal mapping of the gene to 10p within the autosomal recessive megaloblastic anemia (MGA1) region

27 September 2017

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Identification of rat yolk sac target protein of teratogenic antibodies, gp280, as intrinsic factor-cobalamin receptor

27 September 2017

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Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components

27 September 2017

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Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence

27 September 2017

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Characterization of a 280-kD protein restricted to the coated pits of the renal brush border and the epithelial cells of the yolk sac. Teratogenic effect of the specific monoclonal antibodies

27 September 2017

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The cytoplasmic domain of the hyaluronan receptor for endocytosis (HARE) contains multiple endocytic motifs targeting coated pit-mediated internalization

27 September 2017

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Adaptor protein disabled-2 modulates low density lipoprotein receptor synthesis in fibroblasts from patients with autosomal recessive hypercholesterolaemia.

27 September 2017

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Autosomal recessive hypercholesterolaemia: discrimination of ARH protein and LDLR function in the homozygous FH phenotype

29 November 2018

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Elucidation of megalin/LRP2-dependent endocytic transport processes in the larval zebrafish pronephros

29 November 2018

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