Molecular testing in malignant melanoma (Q38012416)

27 August 2017

title

Molecular testing in malignant melanoma (English)

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27 August 2017

Allie H Grossmann

1

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27 August 2017

Kenneth F Grossmann

series ordinal

2

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27 August 2017

Michelle L Wallander

series ordinal

3

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27 August 2017

publication date

1 June 2012

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27 August 2017

published in

Diagnostic Cytopathology

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27 August 2017

volume

40

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27 August 2017

issue

6

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27 August 2017

page(s)

503-510

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Cutaneous melanoma: a model to study cancer metastasis

27 August 2017

cites work

1 reference

Management of cutaneous melanoma

21 January 2018

1 reference

Factors associated with response to high-dose interleukin-2 in patients with metastatic melanoma

21 January 2018

1 reference

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

21 January 2018

1 reference

BRAF targeted therapy changes the treatment paradigm in melanoma

21 January 2018

1 reference

Targeted therapy for melanoma: a primer

21 January 2018

1 reference

Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics

21 January 2018

1 reference

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants

21 January 2018

1 reference

High frequency of BRAF mutations in nevi

21 January 2018

1 reference

BRAF and NRAS mutations in melanoma and melanocytic nevi

21 January 2018

1 reference

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

1 reference

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

21 January 2018

1 reference

Distinct sets of genetic alterations in melanoma

21 January 2018

1 reference

A comprehensive catalogue of somatic mutations from a human cancer genome

21 January 2018

1 reference

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

21 January 2018

1 reference

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

1 reference

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

21 January 2018

1 reference

Elevated CRAF as a potential mechanism of acquired resistance to BRAF inhibition in melanoma

21 January 2018

1 reference

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 January 2018

1 reference

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

21 January 2018

1 reference

Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy.

21 January 2018

1 reference

Combinatorial treatments that overcome PDGFRβ-driven resistance of melanoma cells to V600EB-RAF inhibition

21 January 2018

1 reference

NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing.

21 January 2018

1 reference

Genetic interaction between NRAS and BRAF mutations and PTEN/MMAC1 inactivation in melanoma

21 January 2018

1 reference

Frequencies of NRAS and BRAF mutations increase from the radial to the vertical growth phase in cutaneous melanoma

21 January 2018

1 reference

PI3-kinase subunits are infrequent somatic targets in melanoma.

21 January 2018

1 reference

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer

21 January 2018

1 reference

A novel AKT3 mutation in melanoma tumours and cell lines

21 January 2018

1 reference

PTEN signaling pathways in melanoma

21 January 2018

1 reference

Epigenetic PTEN silencing in malignant melanomas without PTEN mutation

21 January 2018

1 reference

The PI3K pathway as drug target in human cancer

21 January 2018

1 reference

Essential role for nuclear PTEN in maintaining chromosomal integrity

21 January 2018

1 reference

Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

21 January 2018

1 reference

PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells

21 January 2018

1 reference

RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF

21 January 2018

1 reference

Determinants of BRAF mutations in primary melanomas

21 January 2018

1 reference

Genetic aberrations in primary esophageal melanomas: molecular analysis of c-KIT, PDGFR, KRAS, NRAS and BRAF in a series of 10 cases.

21 January 2018

1 reference

BRAF and NRAS mutations are uncommon in melanomas arising in diverse internal organs

21 January 2018

1 reference

Lack of BRAF mutation in primary uveal melanoma.

21 January 2018

1 reference

Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site

21 January 2018

1 reference

Somatic activation of KIT in distinct subtypes of melanoma

21 January 2018

1 reference

KIT gene mutations and copy number in melanoma subtypes

21 January 2018

1 reference

Pathological activation of KIT in metastatic tumors of acral and mucosal melanomas

21 January 2018

1 reference

Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type

21 January 2018

1 reference

Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT

21 January 2018

1 reference

L576P KIT mutation in anal melanomas correlates with KIT protein expression and is sensitive to specific kinase inhibition

21 January 2018

1 reference

C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma

21 January 2018

1 reference

Analysis of c-KIT expression and KIT gene mutation in human mucosal melanomas

21 January 2018

1 reference

KIT mutations in ocular melanoma: frequency and anatomic distribution

21 January 2018

1 reference

Major response to imatinib mesylate in KIT-mutated melanoma.

21 January 2018

1 reference

Dose-dependent, complete response to imatinib of a metastatic mucosal melanoma with a K642E KIT mutation

21 January 2018

1 reference

Anal mucosal melanoma with KIT-activating mutation and response to imatinib therapy--case report and review of the literature

21 January 2018

1 reference

Response to imatinib mesylate depends on the presence of the V559A-mutated KIT oncogene

21 January 2018

1 reference

Melanoma from bench to bedside: meeting report from the 6th international melanoma congress.

21 January 2018

1 reference

c-KIT mutation analysis for diagnosis of gastrointestinal stromal tumors in fine needle aspiration specimens

21 January 2018

1 reference

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

21 January 2018

1 reference

c-Met is a potentially new therapeutic target for treatment of human melanoma

21 January 2018

1 reference

MicroRNA-34a inhibits uveal melanoma cell proliferation and migration through downregulation of c-Met.

21 January 2018

1 reference

Signaling networks in cutaneous melanoma metastasis identified by complementary DNA microarrays

21 January 2018

1 reference

Expression of the c-Met Proteins in Malignant Skin Cancers

21 January 2018

1 reference

PAX3 and SOX10 activate MET receptor expression in melanoma

21 January 2018

1 reference

MET oncogene inhibition as a potential target of therapy for uveal melanomas.

21 January 2018

1 reference

Phase I/II study of GSK2118436, a selective inhibitor of oncogenic mutant BRAF kinase, in patients with metastatic melanoma and other solid tumors

21 January 2018

1 reference

Outcome in 846 cutaneous melanoma patients from a single center after a negative sentinel node biopsy

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Mutations of PIK3CA are rare in cutaneous melanoma

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Epigenetic silencing of the PTEN gene in melanoma

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/DC.22810

1 reference

27 August 2017

1 reference