Curcumin and neurodegenerative diseases: a perspective (Q38016212)

27 August 2017

Curcumin and neurodegenerative diseases: a perspective (English)

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27 August 2017

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Altaf S Darvesh

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27 August 2017

Richard T Carroll

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27 August 2017

Anupam Bishayee

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27 August 2017

Nicholas A Novotny

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27 August 2017

Werner J Geldenhuys

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27 August 2017

Cornelis J Van der Schyf

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27 August 2017

language of work or name

English

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publication date

6 June 2012

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Expert Opinion on Investigational Drugs

27 August 2017

18

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based on heuristic

inferred from page(s)

published in

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27 August 2017

21

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27 August 2017

8

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27 August 2017

1123-1140

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Plant polyphenols: are they the new magic bullet?

27 August 2017

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Plant polyphenols as dietary antioxidants in human health and disease

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The role of polyphenolic antioxidants in health, disease, and aging

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

21 January 2018

Polyphenols and aging

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Cancer prevention and treatment with resveratrol: from rodent studies to clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin and liver cancer: a review

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

21 January 2018

The targets of curcumin.

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Molecular orbital basis for yellow curry spice curcumin's prevention of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin as a therapeutic agent: the evidence from in vitro, animal and human studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The effect of curcumin (turmeric) on Alzheimer's disease: An overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Botanical phenolics and brain health

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Naturally occurring phytochemicals for the prevention of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neuroprotective and neurotrophic curcuminoids to treat stroke: a translational perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

An overview of curcumin in neurological disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The effects of curcumin on depressive-like behaviors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Evaluation of antidepressant-like activity of novel water-soluble curcumin formulations and St. John's wort in behavioral paradigms of despair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

2009 Alzheimer's disease facts and figures

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Nutraceutical antioxidants as novel neuroprotective agents

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Inflammation in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Benefits from dietary polyphenols for brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Vitagenes, dietary antioxidants and neuroprotection in neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Natural antioxidants protect neurons in Alzheimer's disease and Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin: the Indian solid gold

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Lesson learned from nature for the development of novel anti-cancer agents: implication of isoflavone, curcumin, and their synthetic analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Natural products of dietary origin as lead compounds in virtual screening and drug design

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Bioavailability of curcumin: problems and promises

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin: a potential neuroprotective agent in Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Effect of curcumin-associated and lipid ligand-functionalized nanoliposomes on aggregation of the Alzheimer's Aβ peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Conundrum and therapeutic potential of curcumin in drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Safety and pharmacokinetics of a solid lipid curcumin particle formulation in osteosarcoma patients and healthy volunteers

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin nanoformulations: a future nanomedicine for cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Mechanisms of combined action of different chemopreventive dietary compounds: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Improving the oral bioavailability of beneficial polyphenols through designed synergies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Quantitation of chemopreventive synergism between (-)-epigallocatechin-3-gallate and curcumin in normal, premalignant and malignant human oral epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

How curcumin works preferentially with water soluble antioxidants

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin as "Curecumin": from kitchen to clinic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin in clinical practice: myth or reality?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin and Alzheimer disease: this marriage is not to be performed

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Antioxidant and radical scavenging properties of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Inflammation and cancer: how hot is the link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Anti-inflammatory activity of natural dietary flavonoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Effects of flavonoids and other polyphenols on inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Nuclear factor-kappaB activation: from bench to bedside

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The p60 tumor necrosis factor (TNF) receptor-associated kinase (TRAK) binds residues 344-397 within the cytoplasmic domain involved in TNF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Modulation of transcription factors by curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neuroprotective effects of curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Oxidative stress and neurodegeneration: where are we now?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The brain as a target of inflammation: common pathways link inflammatory and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Discovery of curcumin, a component of golden spice, and its miraculous biological activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

New therapeutic strategy for Parkinson's and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Anti-Parkinsonian drug discovery from herbal medicines: what have we got from neurotoxic models?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Revisiting dietary antioxidants, neurodegeneration and dementia

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Natural substances and Alzheimer's disease: from preclinical studies to evidence based medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Apolipoprotein E polymorphism and Alzheimer disease: The Indo-US Cross-National Dementia Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Incidence of Alzheimer's disease in a rural community in India: the Indo-US study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curry consumption and cognitive function in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Current and future therapy in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Oxidative stress hypothesis in Alzheimer's disease: a reappraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neuroinflammation in Alzheimer's disease: different molecular targets and potential therapeutic agents including curcumin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

REVIEW: Curcumin and Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

A potential role of the curry spice curcumin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Why pleiotropic interventions are needed for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin protected PC12 cells against beta-amyloid-induced toxicity through the inhibition of oxidative damage and tau hyperphosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Optimized turmeric extracts have potent anti-amyloidogenic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

A new target for amyloid beta toxicity validated by standard and high-throughput electrophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

ApoE3 mediated poly(butyl) cyanoacrylate nanoparticles containing curcumin: study of enhanced activity of curcumin against beta amyloid induced cytotoxicity using in vitro cell culture model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Potential protection of curcumin against intracellular amyloid beta-induced toxicity in cultured rat prefrontal cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Increased expression of miRNA-146a in Alzheimer's disease transgenic mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin mediates presenilin-1 activity to reduce β-amyloid production in a model of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Phenolic anti-inflammatory antioxidant reversal of Abeta-induced cognitive deficits and neuropathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Consumption of grape seed extract prevents amyloid-beta deposition and attenuates inflammation in brain of an Alzheimer's disease mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Phenolic compounds prevent Alzheimer's pathology through different effects on the amyloid-beta aggregation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Modulation of anxiety behavior by intranasally administered vaccinia virus complement control protein and curcumin in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Evaluating potential of curcumin loaded solid lipid nanoparticles in aluminium induced behavioural, biochemical and histopathological alterations in mice brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Parkinson's disease: clinical features and diagnosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Oxidation chemistry of catecholamines and neuronal degeneration: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neuroinflammation in Parkinson's disease: its role in neuronal death and implications for therapeutic intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Role of inflammation in the pathogenesis of Parkinson's disease: models, mechanisms, and therapeutic interventions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

α-Synuclein in Parkinson disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin inhibits aggregation of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin attenuates 6-hydroxydopamine-induced cytotoxicity by anti-oxidation and nuclear factor-kappa B modulation in MES23.5 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin exposure induces expression of the Parkinson's disease-associated leucine-rich repeat kinase 2 (LRRK2) in rat mesencephalic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin prevents dopaminergic neuronal death through inhibition of the c-Jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Curcumin I protects the dopaminergic cell line SH-SY5Y from 6-hydroxydopamine-induced neurotoxicity through attenuation of p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Manganese complexes of curcumin and its derivatives: evaluation for the radical scavenging ability and neuroprotective activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Neuroprotective properties of the natural phenolic antioxidants curcumin and naringenin but not quercetin and fisetin in a 6-OHDA model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Inhibition of monoamine oxidase-B by the polyphenolic compound, curcumin and its metabolite tetrahydrocurcumin, in a model of Parkinson's disease induced by MPTP neurodegeneration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Chronic dietary supplementation with turmeric protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-mediated neurotoxicity in vivo: implications for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Challenges associated with curcumin therapy in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Six-month randomized, placebo-controlled, double-blind, pilot clinical trial of curcumin in patients with Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Turmeric: the intriguing yellow spice with medicinal properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

The pharmacology of curcumin: is it the degradation products?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Ferulic Acid: therapeutic potential through its antioxidant property.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Protection against beta-amyloid peptide toxicity in vivo with long-term administration of ferulic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Ferulic acid destabilizes preformed beta-amyloid fibrils in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Grape seed polyphenols and curcumin reduce genomic instability events in a transgenic mouse model for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

Bioavailability of Phenolic Antioxidants Associated with Dietary Fiber: Plasma Antioxidant Capacity After Acute and Long-Term Intake in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543784.2012.693479

10.1517/13543784.2012.693479

21 January 2018

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DOI

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27 August 2017

1 reference