Molecular recognition in the human immunodeficiency virus capsid and antiviral design (Q38021264)

27 August 2017

title

Molecular recognition in the human immunodeficiency virus capsid and antiviral design (English)

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27 August 2017

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Rebeca Bocanegra

1

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27 August 2017

Alicia Rodríguez-Huete

2

1 reference

27 August 2017

Miguel Ángel Fuertes

3

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27 August 2017

Marta Del Álamo

4

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27 August 2017

Mauricio G Mateu

5

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27 August 2017

publication date

21 June 2012

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27 August 2017

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27 August 2017

volume

169

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27 August 2017

issue

2

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27 August 2017

page(s)

388-410

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Activity of the small modified amino acid alpha-hydroxy glycineamide on in vitro and in vivo human immunodeficiency virus type 1 capsid assembly and infectivity.

27 August 2017

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The stoichiometry of Gag protein in HIV-1.

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Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

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Modulation of HIV-like particle assembly in vitro by inositol phosphates

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High-throughput human immunodeficiency virus type 1 (HIV-1) full replication assay that includes HIV-1 Vif as an antiviral target

7 January 2021

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Visualization of a missing link in retrovirus capsid assembly

7 January 2021

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Three-dimensional analysis of budding sites and released virus suggests a revised model for HIV-1 morphogenesis

7 January 2021

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Structural and dynamical characterization of tubular HIV-1 capsid protein assemblies by solid state nuclear magnetic resonance and electron microscopy

7 January 2021

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A hot spot of binding energy in a hormone-receptor interface

7 January 2021

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Colony filtration blot: a new screening method for soluble protein expression in Escherichia coli

7 January 2021

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A retroviral chimeric capsid protein reveals the role of the N-terminal β-hairpin in mature core assembly

7 January 2021

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High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

7 January 2021

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Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Conserved and variable features of Gag structure and arrangement in immature retrovirus particles

7 January 2021

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Structural analysis of HIV-1 maturation using cryo-electron tomography

7 January 2021

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7 January 2021

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Electrostatic repulsion, compensatory mutations, and long-range non-additive effects at the dimerization interface of the HIV capsid protein

7 January 2021

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Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly

7 January 2021

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Effect of macromolecular crowding agents on human immunodeficiency virus type 1 capsid protein assembly in vitro.

7 January 2021

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Dendrimers as potential inhibitors of the dimerization of the capsid protein of HIV-1.

7 January 2021

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Larger helical populations in peptides derived from the dimerization helix of the capsid protein of HIV-1 results in peptide binding toward regions other than the "hotspot" interface

7 January 2021

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The isolated major homology region of the HIV capsid protein is mainly unfolded in solution and binds to the intact protein

7 January 2021

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Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1 CA

7 January 2021

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Structure of the HIV-1 Full-Length Capsid Protein in a Conformationally Trapped Unassembled State Induced by Small-Molecule Binding

7 January 2021

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Helix-mediated protein--protein interactions as targets for intervention using foldamers

7 January 2021

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HIV-1 capsid protein forms spherical (immature-like) and tubular (mature-like) particles in vitro: structure switching by pH-induced conformational changes

7 January 2021

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Discovery of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly.

7 January 2021

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7 January 2021

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Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication

7 January 2021

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Cryo-electron microscopy reveals ordered domains in the immature HIV-1 particle

7 January 2021

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Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

7 January 2021

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Assembly and analysis of conical models for the HIV-1 core.

7 January 2021

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Structure of full-length HIV-1 CA: a model for the mature capsid lattice

7 January 2021

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Assembly properties of the human immunodeficiency virus type 1 CA protein

7 January 2021

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7 January 2021

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7 January 2021

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The distribution of ligand-binding pockets around protein-protein interfaces suggests a general mechanism for pocket formation

7 January 2021

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The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization

7 January 2021

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Recent advances in antiretroviral drugs

7 January 2021

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Calculation of protein extinction coefficients from amino acid sequence data

7 January 2021

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Structure of the amino-terminal core domain of the HIV-1 capsid protein

7 January 2021

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Structure and stoichiometry of template-directed recombinant HIV-1 Gag particles

7 January 2021

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Novel targets for HIV therapy

7 January 2021

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In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus

7 January 2021

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A conformational switch controlling HIV-1 morphogenesis

7 January 2021

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Interaction of the Capsid Protein p24 (HIV-1) with Sequence-Derived Peptides: Influence on p24 Dimerization

7 January 2021

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Tripeptide interference with human immunodeficiency virus type 1 morphogenesis

7 January 2021

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Assembly of human immunodeficiency virus precursor gag proteins

7 January 2021

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Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

7 January 2021

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Chemical modulators working at pharmacological interface of target proteins

7 January 2021

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New therapeutic approaches targeted at the late stages of the HIV-1 replication cycle

7 January 2021

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SAR and molecular mechanism study of novel acylhydrazone compounds targeting HIV-1 CA

7 January 2021

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Visualizing HIV-1 assembly

7 January 2021

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Peptide inhibition of HIV-1: current status and future potential

7 January 2021

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Generation of a phagemid mouse recombinant antibody fragment library by multisite-directed mutagenesis.

7 January 2021

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Implications for viral capsid assembly from crystal structures of HIV-1 Gag(1-278) and CA(N)(133-278)

7 January 2021

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Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein

7 January 2021

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High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2

7 January 2021

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Identification of novel interactions in HIV-1 capsid protein assembly by high-resolution mass spectrometry.

7 January 2021

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Key interactions in HIV-1 maturation identified by hydrogen-deuterium exchange.

7 January 2021

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Kinetic analysis of the role of intersubunit interactions in human immunodeficiency virus type 1 capsid protein assembly in vitro

7 January 2021

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Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein

7 January 2021

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Image reconstructions of helical assemblies of the HIV-1 CA protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Discovery of dual inhibitors targeting both HIV-1 capsid and human cyclophilin A to inhibit the assembly and uncoating of the viral capsid

7 January 2021

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HIV-1 capsid protein and cyclophilin a as new targets for anti-AIDS therapeutic agents.

7 January 2021

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The capsid protein of human immunodeficiency virus: interactions of HIV-1 capsid with host protein factors

7 January 2021

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Antibody recognition of picornaviruses and escape from neutralization: a structural view

7 January 2021

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Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein

7 January 2021

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The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly

7 January 2021

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Implications of a quasispecies genome structure: effect of frequent, naturally occurring amino acid substitutions on the antigenicity of foot-and-mouth disease virus

7 January 2021

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Retrovirus capsid protein assembly arrangements

7 January 2021

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The expanding view of protein-protein interactions: complexes involving intrinsically disordered proteins

7 January 2021

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Macromolecular crowding and molecular recognition

7 January 2021

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Foreword to the virus research special issue on "retroviral RNA, protein co-factors and chaperones".

7 January 2021

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Features, processing states, and heterologous protein interactions in the modulation of the retroviral nucleocapsid protein function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Crystal structure of dimeric HIV-1 capsid protein

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Hydrogen/Deuterium Exchange Analysis of HIV-1 Capsid Assembly and Maturation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Hot spots--a review of the protein-protein interface determinant amino-acid residues

7 January 2021

1 reference

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Targeting protein-protein and protein-nucleic acid interactions for anti-HIV therapy

7 January 2021

1 reference

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High-resolution structure of a retroviral capsid hexameric amino-terminal domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Properties and functions of the nucleocapsid protein in virus assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Targeting the assembly of the human immunodeficiency virus type I.

7 January 2021

1 reference

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Antiviral activity of recombinant ankyrin targeted to the capsid domain of HIV-1 Gag polyprotein

7 January 2021

1 reference

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The capsid protein of human immunodeficiency virus: designing inhibitors of capsid assembly

7 January 2021

1 reference

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Biophysical and structural studies on the capsid protein of the human immunodeficiency virus type 1: a new drug target?

7 January 2021

1 reference

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Fullerene-like organization of HIV gag-protein shell in virus-like particles produced by recombinant baculovirus

7 January 2021

1 reference

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Inhibition of infectious human immunodeficiency virus type 1 particle formation by Gag protein-derived peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

X-ray structures of the hexameric building block of the HIV capsid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Atomic-level modelling of the HIV capsid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

New approaches for antiviral targeting of HIV assembly

7 January 2021

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Retroviral capsid assembly: a role for the CA dimer in initiation

7 January 2021

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Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid

7 January 2021

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Effects of macromolecular crowding on the inhibition of virus assembly and virus-cell receptor recognition.

7 January 2021

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Nuclear transport of trimeric assembly intermediates exerts a morphogenetic control on the icosahedral parvovirus capsid

7 January 2021

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Identification of human scFvs targeting atherosclerotic lesions: selection by single round in vivo phage display

7 January 2021

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A novel type of receptor protein, based on the lipocalin scaffold, with specificity for digoxigenin

7 January 2021

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Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization

7 January 2021

1 reference

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Structure of a Monomeric Mutant of the HIV-1 Capsid Protein

7 January 2021

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A peptide inhibitor of HIV-1 assembly in vitro

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Antiviral inhibition of the HIV-1 capsid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

The use of cell-penetrating peptides for drug delivery

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Synthesis and antiviral activities of novel acylhydrazone derivatives targeting HIV-1 capsid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

9 Study of protein subunit association equilibria by elution gel chromatography

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Targeting protein-protein interactions and fragment-based drug discovery.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Blocking HIV-1 virus assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Proteolytic refolding of the HIV-1 capsid protein amino-terminus facilitates viral core assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

HIV type 1 Gag as a target for antiviral therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Targeting Human Immunodeficiency Virus Type 1 Assembly, Maturation and Budding

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Organization of immature human immunodeficiency virus type 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Inhibition of protein-protein interactions using designed molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Design of in vitro symmetric complexes and analysis by hybrid methods reveal mechanisms of HIV capsid assembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

A cell-penetrating helical peptide as a potential HIV-1 inhibitor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Capsid (CA) protein as a novel drug target: recent progress in the research of HIV-1 CA inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

Self-assembly in vitro of purified CA-NC proteins from Rous sarcoma virus and human immunodeficiency virus type 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

inferred from DOI database lookup

7 January 2021

based on heuristic

Functional domains of the capsid protein of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

inferred from DOI database lookup

7 January 2021

based on heuristic

Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FJ.VIRUSRES.2012.06.016

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.VIRUSRES.2012.06.016

1 reference

27 August 2017

1 reference