Metabolism of arsenic and its toxicological relevance (Q38027433)

27 August 2017

title

Metabolism of arsenic and its toxicological relevance (English)

1 reference

27 August 2017

1 reference

2

Seishiro Hirano

1 reference

27 August 2017

Takayuki Watanabe

1

1 reference

27 August 2017

publication date

19 July 2012

1 reference

27 August 2017

published in

Archives of Toxicology

1 reference

27 August 2017

volume

87

1 reference

27 August 2017

issue

6

1 reference

27 August 2017

page(s)

969-979

1 reference

Dimethylarsine and trimethylarsine are potent genotoxins in vitro

27 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Enzymatic methylation of arsenic species and other new approaches to arsenic toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic toxicology: five questions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Generation of thioarsenicals is dependent on the enterohepatic circulation in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Characterization of the intestinal absorption of arsenate, monomethylarsonic acid, and dimethylarsinic acid using the Caco-2 cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Glutathione-S-transferase-omega [MMA(V) reductase] knockout mice: enzyme and arsenic species concentrations in tissues after arsenate administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic speciation in the environment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic metabolism in plants: an inside story.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Environmental distribution, analysis, and toxicity of organometal(loid) compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Metabolism and toxicity of arsenic in human urothelial cells expressing rat arsenic (+3 oxidation state)-methyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

shRNA silencing of AS3MT expression minimizes arsenic methylation capacity of HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Disruption of the arsenic (+3 oxidation state) methyltransferase gene in the mouse alters the phenotype for methylation of arsenic and affects distribution and retention of orally administered arsenate.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Metabolism of arsenic in human liver: the role of membrane transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenite and monomethylarsonous acid generate oxidative stress response in human bladder cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Genetic polymorphisms influencing arsenic metabolism: evidence from Argentina

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Spatial and temporal variations of groundwater arsenic in South and Southeast Asia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

A new role for sulfur in arsenic cycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

High-throughput identification of catalytic redox-active cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Chromatographic separation and identification of products from the reaction of dimethylarsinic acid with hydrogen sulfide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic-induced SUMO-dependent recruitment of RNF4 into PML nuclear bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Purine nucleoside phosphorylase as a cytosolic arsenate reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Determination of configuration of arsenite-glutathione complexes using ECSTM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Differential oxidation of thioredoxin-1, thioredoxin-2, and glutathione by metal ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

A new metabolic pathway of arsenite: arsenic-glutathione complexes are substrates for human arsenic methyltransferase Cyt19.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Diversity of inorganic arsenite biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Cytotoxic effects of S-(dimethylarsino)-glutathione: a putative intermediate metabolite of inorganic arsenicals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

The accumulation and toxicity of methylated arsenicals in endothelial cells: important roles of thiol compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

PML targeting eradicates quiescent leukaemia-initiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

The MRP2/cMOAT transporter and arsenic-glutathione complex formation are required for biliary excretion of arsenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Formation and urinary excretion of arsenic triglutathione and methylarsenic diglutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Active arsenic species produced by GSH-dependent reduction of dimethylarsinic acid cause micronuclei formation in peripheral reticulocytes of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenite binding to synthetic peptides based on the Zn finger region and the estrogen binding region of the human estrogen receptor-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenite binding to synthetic peptides: the effect of increasing length between two cysteines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Dissociation of arsenite-peptide complexes: triphasic nature, rate constants, half-lives, and biological importance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Effects of endogenous hydrogen peroxide and glutathione on the stability of arsenic metabolites in rat bile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Stability of arsenic metabolites, arsenic triglutathione [As(GS)3] and methylarsenic diglutathione [CH3As(GS)2], in rat bile

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Gene expression levels in normal human lymphoblasts with variable sensitivities to arsenite: identification of GGT1 and NFKBIE expression levels as possible biomarkers of susceptibility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic trioxide enhances the therapeutic efficacy of radiation treatment of oral squamous carcinoma while protecting bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic degrades PML or PML-RARalpha through a SUMO-triggered RNF4/ubiquitin-mediated pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

A novel S-adenosyl-L-methionine:arsenic(III) methyltransferase from rat liver cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Multidrug-resistance mdr1a/1b double knockout mice are more sensitive than wild type mice to acute arsenic toxicity, with higher arsenic accumulation in tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic trioxide uptake by human and rat aquaglyceroporins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Binding of dimethylarsinous acid to cys-13alpha of rat hemoglobin is responsible for the retention of arsenic in rat blood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Polymorphisms in the human monomethylarsonic acid (MMA V) reductase/hGSTO1 gene and changes in urinary arsenic profiles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Fifty-year study of lung and bladder cancer mortality in Chile related to arsenic in drinking water.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Identification of arsenite-and arsenic diglutathione-binding proteins in human hepatocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Microprobe XRF mapping and XAS investigations of the intracellular metabolism of arsenic for understanding arsenic-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Formation of dimethylthioarsenicals in red blood cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Comparative toxicity of arsenic metabolites in human bladder cancer EJ-1 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Glutathione plays different roles in the induction of the cytotoxic effects of inorganic and organic arsenic compounds in cultured BALB/c 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

21 January 2018

The ecology of arsenic

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for glutathione synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Preabsorptive metabolism of sodium arsenate by anaerobic microbiota of mouse cecum forms a variety of methylated and thiolated arsenicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Pentavalent arsenic can bind to biomolecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Thio-dimethylarsinate is a common metabolite in urine samples from arsenic-exposed women in Bangladesh

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

A major human arsenic metabolite, dimethylarsinic acid, requires reduced glutathione to induce apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Reactions of arsenic(III) and arsenic(V) species with glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Animal species difference in the uptake of dimethylarsinous acid (DMA(III)) by red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic speciation in the urine and hair of individuals exposed to airborne arsenic through coal-burning in Guizhou, PR China

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Thermodynamics of the As(III)-thiol interaction: arsenite and monomethylarsenite complexes with glutathione, dihydrolipoic acid, and other thiol ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Metabolic differences between two dimethylthioarsenicals in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Theoretical calculations and reaction analysis on the interaction of pentavalent thioarsenicals with biorelevant thiol compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Unraveling arsenic--glutathione connections

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Lack of Methylation of Inorganic Arsenic in the Chimpanzee

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic metabolism by human gut microbiota upon in vitro digestion of contaminated soils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenate transport by sodium/phosphate cotransporter type IIb

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Analysis of arsenic metabolites in HepG2 and AS3MT-transfected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxyl radical

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic speciation and identification of monomethylarsonous acid and monomethylthioarsonic acid in a complex matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Speciation, formation, stability and analytical challenges of human arsenic metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Extraction tool and matrix effects on arsenic speciation analysis in cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Volatile arsenic species released from Escherichia coli expressing the AsIII S-adenosylmethionine methyltransferase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenite methylation by methylvitamin B12 and glutathione does not require an enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Enzymatic methylation of arsenic compounds. III. The marmoset and tamarin, but not the rhesus, monkeys are deficient in methyltransferases that methylate inorganic arsenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Human monomethylarsonic acid (MMA(V)) reductase is a member of the glutathione-S-transferase superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Interactions of sodium selenite, glutathione, arsenic species, and omega class human glutathione transferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic trioxide controls the fate of the PML-RARalpha oncoprotein by directly binding PML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Sulfur-Containing Arsenical Mistaken for Dimethylarsinous Acid [DMA(III)] and Identified as a Natural Metabolite in Urine: Major Implications for Studies on Arsenic Metabolism and Toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Individual Variability in the Human Metabolism of an Arsenic-Containing Carbohydrate, 2′,3′-Dihydroxypropyl 5-deoxy-5-dimethylarsinoyl-β-d-riboside, a Naturally Occurring Arsenical in Seafood

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Human metabolism of arsenolipids present in cod liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

Arsenic methylation capacity, body retention, and null genotypes of glutathione S-transferase M1 and T1 among current arsenic-exposed residents in Taiwan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00204-012-0904-5

10.1007/S00204-012-0904-5

21 January 2018

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1034608192

0 references

1 reference