Mitotic failures in cancer: Aurora B kinase and its potential role in the development of aneuploidy. (Q38030445)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22843098%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Mitotic failures in cancer: Aurora B kinase and its potential role in the development of aneuploidy (English)

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9 February 2020

1

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9 February 2020

author name string

Gábor Méhes

series ordinal

2

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9 February 2020

language of work or name

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29 July 2012

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22843098%20AND%20SRC:MED&resulttype=core&format=json

Pathology Oncology Research

9 February 2020

published in

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9 February 2020

volume

18

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9 February 2020

issue

4

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9 February 2020

page(s)

761-769

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Mitotic kinases as regulators of cell division and its checkpoints

9 February 2020

cites work

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The Aurora kinases: role in cell transformation and tumorigenesis

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Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins

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Aurora kinases: new targets for cancer therapy

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The cellular geography of aurora kinases

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Aurora-A - a guardian of poles

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Aurora A, centrosome structure, and the centrosome cycle

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Aurora kinases as targets for cancer therapy

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Human TPX2 is required for targeting Aurora-A kinase to the spindle

21 January 2018

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Cell cycle kinases as therapeutic targets for cancer

21 January 2018

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Phosphorylation of CDC25B by Aurora-A at the centrosome contributes to the G2-M transition.

21 January 2018

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Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis

21 January 2018

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Characterization of the p53-dependent postmitotic checkpoint following spindle disruption

21 January 2018

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Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

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Genetic instabilities in human cancers

21 January 2018

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Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

21 January 2018

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Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.

21 January 2018

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The chromosome passenger complex is required for fidelity of chromosome transmission and cytokinesis in meiosis of mouse oocytes

21 January 2018

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Aurora-C kinase supports mitotic progression in the absence of Aurora-B

21 January 2018

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Cell cycle-dependent expression and centrosome localization of a third human aurora/Ipl1-related protein kinase, AIK3

21 January 2018

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Genomic organization, expression, and chromosome localization of a third aurora-related kinase gene, Aie1.

21 January 2018

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Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C

21 January 2018

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Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development.

21 January 2018

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Gene expression profiles of the aurora family kinases.

21 January 2018

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Expression of Aurora kinases in human thyroid carcinoma cell lines and tissues.

21 January 2018

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INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Shared and separate functions of polo-like kinases and aurora kinases in cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

21 January 2018

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Chromosomal passengers: conducting cell division

21 January 2018

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Decoding the links between mitosis, cancer, and chemotherapy: The mitotic checkpoint, adaptation, and cell death.

21 January 2018

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Aurora kinase inhibitors--rising stars in cancer therapeutics?

21 January 2018

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Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian Aurora kinases

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

H3 phosphorylation: dual role in mitosis and interphase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic histone H3 phosphorylation by vaccinia-related kinase 1 in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

High chromosome number in hematological cancer cell lines is a negative predictor of response to the inhibition of Aurora B and C by GSK1070916.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Molecular basis of drug resistance in aurora kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-B expression and its correlation with cell proliferation and metastasis in oral cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Expression of Aurora kinases A and B in normal, hyperplastic, and malignant human endometrium: Aurora B as a predictor for poor prognosis in endometrial carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora B kinase expression in laryngeal squamous cell carcinoma and its prognostic implications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Significance of Aurora B overexpression in hepatocellular carcinoma. Aurora B Overexpression in HCC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora kinase inhibitor PHA-739358 suppresses growth of hepatocellular carcinoma in vitro and in a xenograft mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Overexpression of Aurora-A in primary cells interferes with S-phase entry by diminishing Cyclin D1 dependent activities

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Dual degradation of aurora A and B kinases by the histone deacetylase inhibitor LBH589 induces G2-M arrest and apoptosis of renal cancer cells.

21 January 2018

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Aurora-A kinase phosphorylation of Aurora-A kinase interacting protein (AIP) and stabilization of the enzyme-substrate complex

21 January 2018

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ASAP is a novel substrate of the oncogenic mitotic kinase Aurora-A: phosphorylation on Ser625 is essential to spindle formation and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

CDC25B phosphorylation by Aurora-A occurs at the G2/M transition and is inhibited by DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

CENP-A phosphorylation by Aurora-A in prophase is required for enrichment of Aurora-B at inner centromeres and for kinetochore function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora kinases and protein phosphatase 1 mediate chromosome congression through regulation of CENP-E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

N-methyl-D-aspartate receptor signaling results in Aurora kinase-catalyzed CPEB phosphorylation and alpha CaMKII mRNA polyadenylation at synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation of CPE binding factor by Eg2 regulates translation of c-mos mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic regulation of the stability of microtubule plus-end tracking protein EB3 by ubiquitin ligase SIAH-1 and Aurora mitotic kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Negative feedback regulation of Aurora-A via phosphorylation of Fas-associated factor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

The aurora kinase A regulates GSK-3beta in gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation and stabilization of HURP by Aurora-A: implication of HURP as a transforming target of Aurora-A

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Plk1 and Aurora A regulate the depolymerase activity and the cellular localization of Kif2a

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

The centrosomal protein Lats2 is a phosphorylation target of Aurora-A kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

MBD3 and HDAC1, two components of the NuRD complex, are localized at Aurora-A-positive centrosomes in M phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

NDEL1 phosphorylation by Aurora-A kinase is essential for centrosomal maturation, separation, and TACC3 recruitment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation of the par polarity complex protein Par3 at serine 962 is mediated by aurora a and regulates its function in neuronal polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Bora and the kinase Aurora a cooperatively activate the kinase Plk1 and control mitotic entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic kinases regulate MT-polymerizing/MT-bundling activity of DDA3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Identification of V23RalA-Ser194 as a critical mediator for Aurora-A-induced cellular motility and transformation by small pool expression screening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Mitotic kinase Aurora-A phosphorylates RASSF1A and modulates RASSF1A-mediated microtubule interaction and M-phase cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

TRF1 mediates mitotic abnormalities induced by Aurora-A overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation-dependent binding of human transcription factor MOK2 to lamin A/C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Kinetochore microtubule dynamics and attachment stability are regulated by Hec1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation by Aurora B Converts MgcRacGAP to a RhoGAP during Cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-B regulates RNA methyltransferase NSUN2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Phosphorylation of mammalian Sgo2 by Aurora B recruits PP2A and MCAK to centromeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Targeting Aurora kinases for the treatment of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora B expression directly correlates with prostate cancer malignancy and influence prostate cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora B expression in normal testis and seminomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Deregulation of Aurora kinase gene expression in human testicular germ cell tumours.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

High expression of Aurora-B/Aurora and Ipll-like midbody-associated protein (AIM-1) in astrocytomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

A novel treatment strategy targeting Aurora kinases in acute myelogenous leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12253-012-9534-8

Aurora-C kinase supports mitotic progression in the absence of Aurora-B.

21 January 2018

1 reference

12 December 2020

Localization of human TACC3 to mitotic spindles is mediated by phosphorylation on Ser558 by Aurora A: a novel pharmacodynamic method for measuring Aurora A activity

1 reference

12 December 2020

Somatic mutations of the protein kinase gene family in human lung cancer

1 reference

12 December 2020

VX680/MK-0457, a potent and selective Aurora kinase inhibitor, targets both tumor and endothelial cells in clear cell renal cell carcinoma.

1 reference

12 December 2020

Mitotic kinase expression and colorectal cancer progression

1 reference

12 December 2020

A Ran signalling pathway mediated by the mitotic kinase Aurora A in spindle assembly

1 reference

12 December 2020

Aurora2/BTAK/STK15 is involved in cell cycle checkpoint and cell survival of aggressive non‐Hodgkin's lymphoma

1 reference

12 December 2020

Functional implication of human serine/threonine kinase, hAIK, in cell cycle progression

1 reference

12 December 2020

Cdk1, Plks, Auroras, and Neks: the mitotic bodyguards

1 reference

12 December 2020

Increased mitotic phosphorylation of histone H3 attributable to AIM-1/Aurora-B overexpression contributes to chromosome number instability.

1 reference

12 December 2020

10.1007/S12253-012-9534-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22843098%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference