Influence of type 1 diabetes genes on disease progression: similarities and differences between countries (Q38034937)

27 August 2017

Influence of type 1 diabetes genes on disease progression: similarities and differences between countries (English)

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27 August 2017

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Jorma Ilonen

2

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author name string

Johanna Lempainen

series ordinal

1

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27 August 2017

1 October 2012

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27 August 2017

Current diabetes report

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27 August 2017

12

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27 August 2017

5

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27 August 2017

447-455

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https://scigraph.springernature.com/pub.10.1007/s11892-012-0310-7

27 August 2017

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Predictive characteristics of diabetes-associated autoantibodies among children with HLA-conferred disease susceptibility in the general population

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A comparison of the prevalence of islet autoantibodies in children from two countries with differing incidence of diabetes

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Signs of beta-cell autoimmunity in nondiabetic schoolchildren: a comparison between Russian Karelia with a low incidence of type 1 diabetes and Finland with a high incidence rate.

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The HLA class I A locus affects susceptibility to type 1 diabetes

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PTPN22: setting thresholds for autoimmunity

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Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant

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Genetic variation in PTPN22 corresponds to altered function of T and B lymphocytes

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Why is PTPN22 a good candidate susceptibility gene for autoimmune disease?

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Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype

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The PTPN22 C1858T gene variant is associated with proinsulin in new-onset type 1 diabetes

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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Rare variants of IFIH1, a gene implicated in antiviral responses, protect against type 1 diabetes

21 January 2018

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A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region

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Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

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IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells

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Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus.

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

21 January 2018

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21 January 2018

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CTLA-4 gene polymorphism at position 49 in exon 1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease

21 January 2018

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Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes--indication of an increased environmental pressure?

21 January 2018

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21 January 2018

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Shared and distinct genetic variants in type 1 diabetes and celiac disease

21 January 2018

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Association of Non-HLA Genes With Type 1 Diabetes Autoimmunity

21 January 2018

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

21 January 2018

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12 December 2020

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12 December 2020

The Karlsburg type 1 diabetes risk study of a normal schoolchild population: association of beta-cell autoantibodies and human leukocyte antigen-DQB1 alleles in antibody-positive individuals

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12 December 2020

HLA genes associated with autoimmunity and progression to disease in type 1 diabetes

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12 December 2020

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12 December 2020

HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients

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12 December 2020

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

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12 December 2020

Insulin-dependent diabetes mellitus (IDDM) is associated with CTLA4 polymorphisms in multiple ethnic groups

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12 December 2020

IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.

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12 December 2020

Autoimmune polyglandular syndromes

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12 December 2020

Dynamics of diabetes-associated autoantibodies in young children with human leukocyte antigen-conferred risk of type 1 diabetes recruited from the general population

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12 December 2020

Residual β-Cell Function and HLA-A24 in IDDM: Markers of Glycemic Control and Subsequent Development of Diabetic Retinopathy

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12 December 2020

The rising incidence of childhood type 1 diabetes and reduced contribution of high-risk HLA haplotypes

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12 December 2020

The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families

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12 December 2020

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

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12 December 2020

Association of non-HLA genes with type 1 diabetes autoimmunity

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12 December 2020

Effect of the PTPN22 and INS risk genotypes on the progression to clinical type 1 diabetes after the initiation of β-cell autoimmunity

1 reference

12 December 2020

Risk of Diabetic Nephropathy in Type 1 Diabetes Is Associated With Functional Polymorphisms in RANTES Receptor Gene (CCR5): A Sex-Specific Effect

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12 December 2020

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

1 reference

12 December 2020

Signs of beta-cell autoimmunity and HLA-defined diabetes susceptibility in the Finnish population: the sib cohort from the Type 1 Diabetes Prediction and Prevention Study

1 reference

12 December 2020

Association of HLA-A24 with complete beta-cell destruction in IDDM

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12 December 2020

Progression to diabetes in relatives with islet autoantibodies. Is it inevitable?

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12 December 2020

Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease.

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12 December 2020

Effect of HLA class I and class II alleles on progression from autoantibody positivity to overt type 1 diabetes in children with risk-associated class II genotypes

1 reference

12 December 2020

10.1007/S11892-012-0310-7

Identifiers

DOI

1 reference

PubMed ID

22895852

Dimensions Publication ID

27 August 2017

0 references

1 reference

PubMed ID

22895852