Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis (Q38039856)

27 August 2017

title

Nerve growth factor and Alzheimer's disease: new facts for an old hypothesis (English)

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27 August 2017

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Antonino Cattaneo

1

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27 August 2017

Pietro Calissano

series ordinal

2

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27 August 2017

publication date

1 September 2012

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27 August 2017

published in

Molecular Neurobiology

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27 August 2017

volume

46

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27 August 2017

issue

3

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27 August 2017

page(s)

588-604

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The cholinergic hypothesis of geriatric memory dysfunction

27 August 2017

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Alzheimer's disease is a synaptic failure

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21 January 2018

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The nerve growth factor 35 years later

21 January 2018

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Reduction of cortical TrkA but not p75(NTR) protein in early-stage Alzheimer's disease.

21 January 2018

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Loss of nucleus basalis neurons containing trkA immunoreactivity in individuals with mild cognitive impairment and early Alzheimer's disease

21 January 2018

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Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex.

21 January 2018

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Neurotrophic factors in Alzheimer’s disease: role of axonal transport

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Early days of the nerve growth factor proteins.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Intrinsic structural disorder of mouse proNGF.

21 January 2018

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Sortilin is essential for proNGF-induced neuronal cell death

21 January 2018

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The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease

21 January 2018

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Amyloid beta-induced nerve growth factor dysmetabolism in Alzheimer disease.

21 January 2018

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21 January 2018

p75NTR--live or let die.

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Dissecting the diverse actions of pro- and mature neurotrophins

21 January 2018

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Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

21 January 2018

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Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

21 January 2018

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Failure of nicotine-dependent enhancement of synaptic efficacy at Schaffer-collateral CA1 synapses of AD11 anti-nerve growth factor transgenic mice.

21 January 2018

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Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies

21 January 2018

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Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice.

21 January 2018

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On the molecular basis linking Nerve Growth Factor (NGF) to Alzheimer's disease

21 January 2018

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Dissecting NGF interactions with TrkA and p75 receptors by structural and functional studies of an anti-NGF neutralizing antibody

21 January 2018

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Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

21 January 2018

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In the adult hippocampus, chronic nerve growth factor deprivation shifts GABAergic signaling from the hyperpolarizing to the depolarizing direction

21 January 2018

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Early inflammation and immune response mRNAs in the brain of AD11 anti-NGF mice.

21 January 2018

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Inflammatory changes parallel the early stages of Alzheimer disease

21 January 2018

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The classical complement cascade mediates CNS synapse elimination

21 January 2018

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A dual mechanism linking NGF/proNGF imbalance and early inflammation to Alzheimer's disease neurodegeneration in the AD11 anti-NGF mouse model

21 January 2018

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The blood-brain barrier in health and chronic neurodegenerative disorders

21 January 2018

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21 January 2018

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A genomic approach to investigate neuronal apoptosis

21 January 2018

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Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Early release and subsequent caspase-mediated degradation of cytochrome c in apoptotic cerebellar granule cells

21 January 2018

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Cytochrome c, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria

21 January 2018

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Role of the autophagic-lysosomal system on low potassium-induced apoptosis in cultured cerebellar granule cells.

21 January 2018

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Transfer of the apoptotic message in sister cultures of cerebellar neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Selective vulnerability of corticocortical and hippocampal circuits in aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

NGF and BDNF signaling control amyloidogenic route and Abeta production in hippocampal neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Endogenous Aβ causes cell death via early tau hyperphosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Tau and HMW tau phosphorylation and compartmentalization in apoptotic neuronal PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Antibodies against beta-amyloid reduce Abeta oligomers, glycogen synthase kinase-3beta activation and tau phosphorylation in vivo and in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Interaction of tau protein with the dynactin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Role of tau phosphorylation by glycogen synthase kinase-3beta in the regulation of organelle transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Cytoskeletal transport in the aging brain: focus on the cholinergic system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Altered cellular distribution of phospho-tau proteins coincides with impaired retrograde axonal transport in neurons of aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Neurotrophins and their receptors: a convergence point for many signalling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Trk receptors: roles in neuronal signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Tyrosine kinase nerve growth factor receptor switches from prosurvival to proapoptotic activity via Abeta-mediated phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Phosphorylation regulates tau interactions with Src homology 3 domains of phosphatidylinositol 3-kinase, phospholipase Cgamma1, Grb2, and Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Signal transduction through tyrosine-phosphorylated C-terminal fragments of amyloid precursor protein via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Cdk5 deregulation in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Cleavage of p75 neurotrophin receptor by alpha-secretase and gamma-secretase requires specific receptor domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Toward structural elucidation of the gamma-secretase complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

The role of the p75 neurotrophin receptor in cholinergic dysfunction in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Beta-amyloid(1-42) induces neuronal death through the p75 neurotrophin receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Neurotrophin receptor-based strategies for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

APP is phosphorylated by TrkA and regulates NGF/TrkA signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Amyloid beta mediates memory formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Amyloid beta as a regulator of lipid homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Neurotrophins: mediators and modulators of pain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Nerve growth factor for the treatment of diabetic neuropathy: what went wrong, what went right, and what does the future hold?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Delivery of NGF to the brain: intranasal versus ocular administration in anti-NGF transgenic mice.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Development of a non invasive NGF-based therapy for Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Mutations in the TRKA/NGF receptor gene in patients with congenital insensitivity to pain with anhidrosis

21 January 2018

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https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Molecular basis of congenital insensitivity to pain with anhidrosis (CIPA): mutations and polymorphisms in TRKA (NTRK1) gene encoding the receptor tyrosine kinase for nerve growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

In vitro receptor binding properties of a "painless" NGF mutein, linked to hereditary sensory autonomic neuropathy type V.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

A modular PIP2 binding site as a determinant of capsaicin receptor sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

Intranasal "painless" human Nerve Growth Factor [corrected] slows amyloid neurodegeneration and prevents memory deficits in App X PS1 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-012-8310-9

The production of amyloid beta peptide is a critical requirement for the viability of central neurons.

21 January 2018

1 reference

12 December 2020

Traffic at the intersection of neurotrophic factor signaling and neurodegeneration

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12 December 2020

The effects of nerve growth factor and its antiserum on the postnatal development and survival after injury of sensory neurons in rat dorsal root ganglia

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12 December 2020

Activation of the amyloidogenic route by NGF deprivation induces apoptotic death in PC12 cells

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12 December 2020

Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis

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12 December 2020

Nerve growth factor and Alzheimer's disease

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12 December 2020

Time window in cholinomimetic ability to rescue long-term potentiation in neurodegenerating anti-nerve growth factor mice

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12 December 2020

Effects of the extract of the mouse submaxillary salivary glands on the sympathetic system of mammals

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12 December 2020

Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis

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12 December 2020

Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.

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12 December 2020

The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology

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12 December 2020

Environmental enrichment delays the onset of memory deficits and reduces neuropathological hallmarks in a mouse model of Alzheimer-like neurodegeneration

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12 December 2020

Possible influence of a non-synonymous polymorphism located in the NGF precursor on susceptibility to late-onset Alzheimer's disease and mild cognitive impairment.

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12 December 2020

Rapid tyrosine phosphorylation of neuronal proteins including tau and focal adhesion kinase in response to amyloid-beta peptide exposure: involvement of Src family protein kinases.

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12 December 2020

Granule neuron DNA damage following deafferentation in adult rats cerebellar cortex: a lesion model

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12 December 2020

Towards non invasive nerve growth factor therapies for Alzheimer's disease

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12 December 2020

Proteasome involvement and accumulation of ubiquitinated proteins in cerebellar granule neurons undergoing apoptosis

1 reference

12 December 2020

10.1007/S12035-012-8310-9

Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1050821385

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