Affinity proteomics: the role of specific binding reagents in human proteome analysis (Q38042457)

27 August 2017

Affinity proteomics: the role of specific binding reagents in human proteome analysis (English)

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27 August 2017

Oda Stoevesandt

1

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PubMed ID

22967077

27 August 2017

Michael J Taussig

series ordinal

2

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PubMed ID

22967077

27 August 2017

language of work or name

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1 August 2012

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Expert Review of Proteomics

27 August 2017

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27 August 2017

9

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27 August 2017

4

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27 August 2017

401-414

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Affinity as a tool in life science

27 August 2017

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Affinity reagent resources for human proteome detection: initiatives and perspectives

21 January 2018

1 reference

Should the Human Proteome Project be gene- or protein-centric?

21 January 2018

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A genecentric Human Protein Atlas for expression profiles based on antibodies

21 January 2018

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Distinguishing protein-coding and noncoding genes in the human genome

21 January 2018

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Beyond natural antibodies: the power of in vitro display technologies

21 January 2018

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Towards a knowledge-based Human Protein Atlas

21 January 2018

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A whole-genome bioinformatics approach to selection of antigens for systematic antibody generation

21 January 2018

1 reference

A global view of protein expression in human cells, tissues, and organs

21 January 2018

1 reference

Antibodypedia, a portal for sharing antibody and antigen validation data

21 January 2018

1 reference

A human scFv antibody generation pipeline for proteome research

21 January 2018

1 reference

A roadmap to generate renewable protein binders to the human proteome

21 January 2018

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A human proteome detection and quantitation project

21 January 2018

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Protein production and purification

21 January 2018

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Human protein factory for converting the transcriptome into an in vitro-expressed proteome,.

21 January 2018

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Antibody specificity profiling on functional protein microarrays

21 January 2018

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Strategy for surveying the proteome using affinity proteomics and mass spectrometry

21 January 2018

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Proteome wide screening using peptide affinity capture

21 January 2018

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High-throughput antibody generation using multiplexed immunization and immunogen array analysis.

21 January 2018

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Comparison and critical analysis of robotized technology for monoclonal antibody high-throughput production.

21 January 2018

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Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells

21 January 2018

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Generating recombinant antibodies to the complete human proteome

21 January 2018

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Chaperone-assisted crystallography with DARPins

21 January 2018

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Application of phage display to high throughput antibody generation and characterization

21 January 2018

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Towards proteome scale antibody selections using phage display

21 January 2018

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Generating a panel of highly specific antibodies to 20 human SH2 domains by phage display

21 January 2018

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Using phage display to select antibodies recognizing post-translational modifications independently of sequence context

21 January 2018

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Two-state selection of conformation-specific antibodies

21 January 2018

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Camelid immunoglobulins and nanobody technology.

21 January 2018

1 reference

Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies

21 January 2018

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Modulation of protein properties in living cells using nanobodies

21 January 2018

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Targeting and tracing antigens in live cells with fluorescent nanobodies

21 January 2018

1 reference

A designed ankyrin repeat protein evolved to picomolar affinity to Her2

21 January 2018

1 reference

Selection and characterization of DARPins specific for the neurotensin receptor 1

21 January 2018

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Intracellular kinase inhibitors selected from combinatorial libraries of designed ankyrin repeat proteins

21 January 2018

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Isolation of intracellular proteinase inhibitors derived from designed ankyrin repeat proteins by genetic screening

21 January 2018

1 reference

Inhibition of caspase-2 by a designed ankyrin repeat protein: specificity, structure, and inhibition mechanism

21 January 2018

1 reference

Knowledge-based design of reagentless fluorescent biosensors from a designed ankyrin repeat protein

21 January 2018

1 reference

A novel fusion toxin derived from an EpCAM-specific designed ankyrin repeat protein has potent antitumor activity

21 January 2018

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Advances in human proteomics at high scale with the SOMAscan proteomics platform

21 January 2018

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Aptamer-based multiplexed proteomic technology for biomarker discovery

21 January 2018

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Unlocking biomarker discovery: large scale application of aptamer proteomic technology for early detection of lung cancer

21 January 2018

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Age-dependent changes in the cerebrospinal fluid proteome by slow off-rate modified aptamer array

21 January 2018

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The epitope space of the human proteome

21 January 2018

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EpiC: an open resource for exploring epitopes to aid antibody-based experiments

21 January 2018

1 reference

A community standard format for the representation of protein affinity reagents

21 January 2018

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The Human Protein Atlas--a tool for pathology

21 January 2018

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Overcoming the dynamic range problem in mass spectrometry-based shotgun proteomics

21 January 2018

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Coupling immunoaffinity techniques with MS for quantitative analysis of low-abundance protein biomarkers

21 January 2018

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Mapping protein interactions by combining antibody affinity maturation and mass spectrometry

21 January 2018

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Diagnostic and prognostic biomarker discovery strategies for autoimmune disorders

21 January 2018

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Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

21 January 2018

1 reference

An automated and multiplexed method for high throughput peptide immunoaffinity enrichment and multiple reaction monitoring mass spectrometry-based quantification of protein biomarkers

21 January 2018

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Automated screening of monoclonal antibodies for SISCAPA assays using a magnetic bead processor and liquid chromatography-selected reaction monitoring-mass spectrometry

21 January 2018

1 reference

Anti-peptide antibody screening: selection of high affinity monoclonal reagents by a refined surface plasmon resonance technique

21 January 2018

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MALDI immunoscreening (MiSCREEN): a method for selection of anti-peptide monoclonal antibodies for use in immunoproteomics

21 January 2018

1 reference

Design of high-density antibody microarrays for disease proteomics: key technological issues

21 January 2018

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Targeting peptide termini, a novel immunoaffinity approach to reduce complexity in mass spectrometric protein identification

21 January 2018

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Quantification of target proteins using hydrogel antibody arrays and MALDI time-of-flight mass spectrometry (A2M2S).

21 January 2018

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Performance of combinatorial peptide libraries in capturing the low-abundance proteome of red blood cells. 1. Behavior of mono- to hexapeptides.

21 January 2018

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Equalizer technology--Equal rights for disparate beads

21 January 2018

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Protein microarrays: high-throughput tools for proteomics

21 January 2018

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Reverse-phase versus sandwich antibody microarray, technical comparison from a clinical perspective.

21 January 2018

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Validation and quality control of protein microarray-based analytical methods

21 January 2018

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Antibody-based protein multiplex platforms: technical and operational challenges

21 January 2018

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Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

21 January 2018

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Self-assembling protein microarrays

21 January 2018

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Printing protein arrays from DNA arrays

21 January 2018

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Assessment of antibody specificity using suspension bead arrays.

21 January 2018

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Proteome-wide analysis of the serological response to vaccinia and smallpox

21 January 2018

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Profiling humoral immune responses to P. falciparum infection with protein microarrays

21 January 2018

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Profiling the humoral immune response to infection by using proteome microarrays: high-throughput vaccine and diagnostic antigen discovery

21 January 2018

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Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer

21 January 2018

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Autoantigen discovery with a synthetic human peptidome

21 January 2018

1 reference

Design of recombinant antibody microarrays for complex proteome analysis: choice of sample labeling-tag and solid support

21 January 2018

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Oncoproteomic profiling with antibody microarrays

21 January 2018

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Single-step procedure for the isolation of proteins at near-native conditions from mammalian tissue for proteomic analysis on antibody microarrays.

21 January 2018

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Design of recombinant antibody microarrays for membrane protein profiling of cell lysates and tissue extracts

21 January 2018

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Producing reverse phase protein microarrays from formalin-fixed tissues

21 January 2018

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Discovery of new molecular subtypes in oesophageal adenocarcinoma

21 January 2018

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Functional proteomics can define prognosis and predict pathologic complete response in patients with breast cancer

21 January 2018

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Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML

21 January 2018

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Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells

21 January 2018

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Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling

21 January 2018

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Protein lysate microarray analysis to identify microRNAs regulating estrogen receptor signaling in breast cancer cell lines

21 January 2018

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Tracing pathway activities with kinase inhibitors and reverse phase protein arrays

21 January 2018

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Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis

21 January 2018

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Protein microarrays for multiplex analysis of signal transduction pathways

21 January 2018

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Systems analysis of EGF receptor signaling dynamics with microwestern arrays

21 January 2018

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A single fixation protocol for proteome-wide immunofluorescence localization studies

21 January 2018

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Defining the transcriptome and proteome in three functionally different human cell lines

21 January 2018

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Correlations between RNA and protein expression profiles in 23 human cell lines

21 January 2018

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Sensitive plasma protein analysis by microparticle-based proximity ligation assays

21 January 2018

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Characterizing proteins and their interactions in cells and tissues using the in situ proximity ligation assay

21 January 2018

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High content screening for inhibitors of protein interactions and post-translational modifications in primary cells by proximity ligation

21 January 2018

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Multiple recognition assay reveals prostasomes as promising plasma biomarkers for prostate cancer

21 January 2018

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One-step analysis of protein complexes in microliters of cell lysate

21 January 2018

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Multiplexed immuno-precipitation with 1725 commercially available antibodies to cellular proteins

21 January 2018

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Serum proteome profiling of metastatic breast cancer using recombinant antibody microarrays

21 January 2018

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Plasma proteome profiling reveals biomarker patterns associated with prognosis and therapy selection in glioblastoma multiforme patients.

21 January 2018

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Design of recombinant antibody microarrays for serum protein profiling: targeting of complement proteins

21 January 2018

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Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays

21 January 2018

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Profiling bladder cancer using targeted antibody arrays

21 January 2018

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Comparative application of antibody and gene array for expression profiling in human squamous cell lung carcinoma.

21 January 2018

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Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-related antibodies

21 January 2018

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A novel approach to protein expression profiling using antibody microarrays combined with surface plasmon resonance technology

21 January 2018

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Validation of serum protein profiles by a dual antibody array approach

21 January 2018

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Novel functional profiling approach combining reverse phase protein microarrays and human 3-Dex vivotissue cultures: Expression of apoptosis-related proteins in human colon cancer

21 January 2018

1 reference

Is a gene-centric human proteome project the best way for proteomics to serve biology?

21 January 2018

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Validation of affinity reagents using antigen microarrays

21 January 2018

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21 January 2018

Identifiers

DOI

10.1586/EPR.12.34

1 reference

27 August 2017

1 reference

PubMed ID

22967077