The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans (Q38050514)

27 August 2017

The importance of experimental design and QC samples in large-scale and MS-driven untargeted metabolomic studies of humans (English)

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27 August 2017

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Warwick B Dunn

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27 August 2017

David Broadhurst

4

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author name string

Ian D Wilson

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2

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PubMed ID

23046267

27 August 2017

Andrew W Nicholls

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3

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PubMed ID

23046267

27 August 2017

language of work or name

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1 September 2012

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27 August 2017

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27 August 2017

4

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27 August 2017

2249-2264

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27 August 2017

18

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SNPs: impact on gene function and phenotype

27 August 2017

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Minireview: Epigenetics of obesity and diabetes in humans

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolic signatures of exercise in human plasma

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

HMDB: a knowledgebase for the human metabolome

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolomics by numbers: acquiring and understanding global metabolite data

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

(1)H NMR-based metabonomic investigation of the effect of two different exercise sessions on the metabolic fingerprint of human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolite profiles and the risk of developing diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Robust early pregnancy prediction of later preeclampsia using metabolomic biomarkers

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolic profiling uncovers a phenotypic signature of small for gestational age in early pregnancy.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

NMR metabolomics of MTLn3E breast cancer cells identifies a role for CXCR4 in lipid and choline regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolic profiling reveals key metabolic features of renal cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Cancer detection and biopsy classification using concurrent histopathological and metabolomic analysis of core biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics: the INTERMAP Study

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Reliability of serum metabolite concentrations over a 4-month period using a targeted metabolomic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolomic profiling of human urine in hepatocellular carcinoma patients using gas chromatography/mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.12.204

A pragmatic and readily implemented quality control strategy for HPLC-MS and GC-MS-based metabonomic analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Research issues and strategies for genomic and proteomic biomarker discovery and validation: a statistical perspective

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.12.204

Statistical strategies for avoiding false discoveries in metabolomics and related experiments

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.12.204

Impact of analytical bias in metabonomic studies of human blood serum and plasma.

21 January 2018

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https://api.crossref.org/works/10.4155%2FBIO.12.204

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Metabolic profiling of serum using Ultra Performance Liquid Chromatography and the LTQ-Orbitrap mass spectrometry system

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: application to human urine

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

The metabolome of human placental tissue: investigation of first trimester tissue and changes related to preeclampsia in late pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Global metabolic profiling procedures for urine using UPLC–MS

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.12.204

Optimizing the use of quality control samples for signal drift correction in large-scale urine metabolic profiling studies

21 January 2018

1 reference

5 May 2024

https://opencitations.net/index/api/v1/citations/10.1021/AC202733Q

Identifiers

DOI

10.4155/BIO.12.204

1 reference

27 August 2017

1 reference

PubMed ID

23046267