Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy (Q37780690)

23 August 2017

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy (English)

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23 August 2017

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David I Broadhurst

2

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Warwick Dunn

object named as

Warwick B Dunn

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1

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Roy Goodacre

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4

object named as

Royston Goodacre

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23 August 2017

5

Julian L Griffin

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23 August 2017

3

Helen J Atherton

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23 August 2017

17 August 2010

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23 August 2017

Chemical Society Reviews

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23 August 2017

40

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23 August 2017

387-426

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23 August 2017

1

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Metabolomics – the link between genotypes and phenotypes

23 August 2017

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Metabolomics by numbers: acquiring and understanding global metabolite data

21 January 2018

1 reference

The Cinderella story of metabolic profiling: does metabolomics get to go to the functional genomics ball?

21 January 2018

1 reference

Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse

21 January 2018

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The nature of systems biology

21 January 2018

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Global metabolic profiling and its role in systems biology to advance personalized medicine in the 21st century

21 January 2018

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Systems biology: Metabonomics.

21 January 2018

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Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

21 January 2018

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Metallomics: the concept and methodology

21 January 2018

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HMDB: a knowledgebase for the human metabolome

21 January 2018

1 reference

Systematic functional analysis of the yeast genome

21 January 2018

1 reference

A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology

21 January 2018

1 reference

The Edinburgh human metabolic network reconstruction and its functional analysis

21 January 2018

1 reference

Global reconstruction of the human metabolic network based on genomic and bibliomic data

21 January 2018

1 reference

A genome-scale, constraint-based approach to systems biology of human metabolism

21 January 2018

1 reference

The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism

21 January 2018

1 reference

Shotgun lipidomics: electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

21 January 2018

1 reference

Database resources in metabolomics: an overview

21 January 2018

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SMPDB: The Small Molecule Pathway Database

21 January 2018

1 reference

The large-scale organization of metabolic networks

21 January 2018

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Hierarchical organization of modularity in metabolic networks

21 January 2018

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Ab initio prediction of metabolic networks using Fourier transform mass spectrometry data

21 January 2018

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Gut flora in health and disease

21 January 2018

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Gut microorganisms, mammalian metabolism and personalized health care

21 January 2018

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21 January 2018

1 reference

Multiple high-throughput analyses monitor the response of E. coli to perturbations

21 January 2018

1 reference

Expanding metabolic networks: scopes of compounds, robustness, and evolution

21 January 2018

1 reference

Mechanisms of disease:Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes

21 January 2018

1 reference

Riboswitch RNAs: using RNA to sense cellular metabolism

21 January 2018

1 reference

'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data

21 January 2018

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Measuring the metabolome: current analytical technologies

21 January 2018

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A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

21 January 2018

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The role of analytical sciences in medical systems biology

21 January 2018

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Quantitative Analysis of Urine Vapor and Breath by Gas-Liquid Partition Chromatography

21 January 2018

1 reference

An investigation of tumor 1H nuclear magnetic resonance spectra by the application of chemometric techniques

21 January 2018

1 reference

High-resolution 1H nuclear magnetic resonance study of cerebral hypoxia in vivo

21 January 2018

1 reference

Metabolomics, machine learning and modelling: towards an understanding of the language of cells.

21 January 2018

1 reference

A new chemical diagnostic method for inborn errors of metabolism by mass spectrometry-rapid, practical, and simultaneous urinary metabolites analysis

21 January 2018

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21 January 2018

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The Sequence of the Human Genome

21 January 2018

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Metabolite profiling for plant functional genomics

21 January 2018

1 reference

Genetics. Getting closer to the whole picture.

21 January 2018

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Bridging the gap between systems biology and medicine

21 January 2018

1 reference

Modeling the heart--from genes to cells to the whole organ

21 January 2018

1 reference

Bringing metabolomics data into the forefront of systems biology

21 January 2018

1 reference

Systems biology, metabolic modelling and metabolomics in drug discovery and development

21 January 2018

1 reference

A metabolome pipeline: from concept to data to knowledge

21 January 2018

1 reference

Global metabolic profiling analysis on human urine by UPLC-TOFMS: issues and method validation in nutritional metabolomics

21 January 2018

1 reference

A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols

21 January 2018

1 reference

Global metabolic profiling of Escherichia coli cultures: an evaluation of methods for quenching and extraction of intracellular metabolites.

21 January 2018

1 reference

Development of a robust and repeatable UPLC-MS method for the long-term metabolomic study of human serum

21 January 2018

1 reference

Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets

21 January 2018

1 reference

Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era

21 January 2018

1 reference

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

21 January 2018

1 reference

Analytical strategies for LC-MS-based targeted metabolomics

21 January 2018

1 reference

Metabolomic identification of novel biomarkers of myocardial ischemia.

21 January 2018

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Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

21 January 2018

1 reference

Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics

21 January 2018

1 reference

Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'.

21 January 2018

1 reference

Current trends and future requirements for the mass spectrometric investigation of microbial, mammalian and plant metabolomes

21 January 2018

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Statistical strategies for avoiding false discoveries in metabolomics and related experiments

21 January 2018

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A pragmatic and readily implemented quality control strategy for HPLC-MS and GC-MS-based metabonomic analysis.

21 January 2018

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Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping.

21 January 2018

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Bias as a threat to the validity of cancer molecular-marker research

21 January 2018

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Impact of analytical bias in metabonomic studies of human blood serum and plasma.

21 January 2018

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High-throughput tissue extraction protocol for NMR- and MS-based metabolomics

21 January 2018

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Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry.

21 January 2018

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Investigation of human blood plasma sample preparation for performing metabolomics using ultrahigh performance liquid chromatography/mass spectrometry

21 January 2018

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UPLC-MS-based analysis of human plasma for metabonomics using solvent precipitation or solid phase extraction

21 January 2018

1 reference

Phospholipid capture combined with non-linear chromatographic correction for improved serum metabolite profiling

21 January 2018

1 reference

High temperature-ultra performance liquid chromatography-mass spectrometry for the metabonomic analysis of Zucker rat urine

21 January 2018

1 reference

A comprehensive urinary metabolomic approach for identifying kidney cancerr

21 January 2018

1 reference

Metabolic fingerprinting in disease diagnosis: biomedical applications of infrared and Raman spectroscopy.

21 January 2018

1 reference

Metabolomic profiling to develop blood biomarkers for Parkinson's disease.

21 January 2018

1 reference

Mass spectrometry-based metabolomics

21 January 2018

1 reference

Mass spectrometry in metabolome analysis.

21 January 2018

1 reference

Flow-injection electrospray ionization mass spectrometry of crude cell extracts for high-throughput bacterial identification

21 January 2018

1 reference

Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the spectral stitching method.

21 January 2018

1 reference

Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum

21 January 2018

1 reference

GC-MS with ethyl chloroformate derivatization for comprehensive analysis of metabolites in serum and its application to human uremia

21 January 2018

1 reference

Closed-loop, multiobjective optimization of analytical instrumentation: gas chromatography/time-of-flight mass spectrometry of the metabolomes of human serum and of yeast fermentations.

21 January 2018

1 reference

Higher mass loadability in comprehensive two-dimensional gas chromatography-mass spectrometry for improved analytical performance in metabolomics analysis.

21 January 2018

1 reference

Recent advancements in comprehensive two-dimensional separations with chemometrics

21 January 2018

1 reference

An introduction to liquid chromatography-mass spectrometry instrumentation applied in plant metabolomic analyses

21 January 2018

1 reference

High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies.

21 January 2018

1 reference

Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data analysis

21 January 2018

1 reference

Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis

21 January 2018

1 reference

Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules

21 January 2018

1 reference

Derivatisation for liquid chromatography/electrospray mass spectrometry: synthesis of pyridinium compounds and their amine and carboxylic acid derivatives

21 January 2018

1 reference

Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics

21 January 2018

1 reference

Capillary electrophoresis-fourier transform ion cyclotron resonance mass spectrometry for the identification of cationic metabolites via a pH-mediated stacking-transient isotachophoretic method

21 January 2018

1 reference

Quantitative Metabolome Analysis Using Capillary Electrophoresis Mass Spectrometry

21 January 2018

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MR-determined metabolic phenotype of breast cancer in prediction of lymphatic spread, grade, and hormone status

21 January 2018

1 reference

The biochemical profile of rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy.

21 January 2018

1 reference

High-resolution diffusion and relaxation-edited magic angle spinning 1H NMR spectroscopy of intact liver tissue

21 January 2018

1 reference

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one- and two-dimensional magic-angle spinning (1)H NMR spectroscopy

21 January 2018

1 reference

Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery

21 January 2018

1 reference

Evaluation of predicted network modules in yeast metabolism using NMR-based metabolite profiling

21 January 2018

1 reference

High-resolution capillary tube NMR. A miniaturized 5-microL high-sensitivity TXI probe for mass-limited samples, off-line LC NMR, and HT NMR.

21 January 2018

1 reference

The application of LC-NMR and LC-SPE-NMR to compositional studies of natural organic matter

21 January 2018

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Real-time metabolic imaging

21 January 2018

1 reference

Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy.

21 January 2018

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Targeted profiling: quantitative analysis of 1H NMR metabolomics data

21 January 2018

1 reference

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

21 January 2018

1 reference

Time-domain Bayesian detection and estimation of noisy damped sinusoidal signals applied to NMR spectroscopy.

21 January 2018

1 reference

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

21 January 2018

1 reference

A common open representation of mass spectrometry data and its application to proteomics research

21 January 2018

1 reference

Five years of progress in the Standardization of Proteomics Data 4th Annual Spring Workshop of the HUPO-Proteomics Standards Initiative April 23-25, 2007 Ecole Nationale Supérieure (ENS), Lyon, France

21 January 2018

1 reference

Metabolic profiling using direct infusion electrospray ionisation mass spectrometry for the characterisation of olive oils

21 January 2018

1 reference

Spectral relative standard deviation: a practical benchmark in metabolomics

21 January 2018

1 reference

Automated work-flow for processing high-resolution direct infusion electrospray ionization mass spectral fingerprints

21 January 2018

1 reference

Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum

21 January 2018

1 reference

MetAlign: interface-driven, versatile metabolomics tool for hyphenated full-scan mass spectrometry data preprocessing

21 January 2018

1 reference

Processing methods for differential analysis of LC/MS profile data

21 January 2018

1 reference

MathDAMP: a package for differential analysis of metabolite profiles

21 January 2018

1 reference

Data processing for mass spectrometry-based metabolomics

21 January 2018

1 reference

Centering, scaling, and transformations: improving the biological information content of metabolomics data

21 January 2018

1 reference

Metabonomics techniques and applications to pharmaceutical research & development

21 January 2018

1 reference

Automated principal component-based orthogonal signal correction applied to fused near infrared-mid-infrared spectra of French olive oils

21 January 2018

1 reference

Orthogonal projections to latent structures (O-PLS)

21 January 2018

1 reference

Classification of pyrolysis mass spectra by fuzzy multivariate rule induction-comparison with regression, K-nearest neighbour, neural and decision-tree methods

21 January 2018

1 reference

Warmr: a data mining tool for chemical data

21 January 2018

1 reference

Identifying Important Risk Factors for Survival in Kidney Graft Failure Patients Using Random Survival Forests

21 January 2018

1 reference

Multiobjective optimization in bioinformatics and computational biology

21 January 2018

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Making sense of the metabolome using evolutionary computation: seeing the wood with the trees

21 January 2018

1 reference

Metabolomic biomarkers: search, discovery and validation

21 January 2018

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Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

21 January 2018

1 reference

Variable selection using iterative reformulation of training set models for discrimination of samples: application to gas chromatography/mass spectrometry of mouse urinary metabolites

21 January 2018

1 reference

Genetic algorithms for simultaneous variable and sample selection in metabonomics

21 January 2018

1 reference

Genetic algorithms as a method for variable selection in multiple linear regression and partial least squares regression, with applications to pyrolysis mass spectrometry

21 January 2018

1 reference

Genetic algorithm optimization for pre-processing and variable selection of spectroscopic data

21 January 2018

1 reference

Pitfalls of supervised feature selection

21 January 2018

1 reference

Measuring diagnostic and predictive accuracy in disease management: an introduction to receiver operating characteristic (ROC) analysis

21 January 2018

1 reference

Basic principles of ROC analysis

21 January 2018

1 reference

Serum metabolomics reveals many novel metabolic markers of heart failure, including pseudouridine and 2-oxoglutarate

21 January 2018

1 reference

Data-driven modelling of signal-transduction networks

21 January 2018

1 reference

Theodor Bücher Lecture. Metabolomics, modelling and machine learning in systems biology - towards an understanding of the languages of cells. Delivered on 3 July 2005 at the 30th FEBS Congress and the 9th IUBMB conference in Budapest.

21 January 2018

1 reference

Metabolomics and systems biology: making sense of the soup

21 January 2018

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Contradicted and initially stronger effects in highly cited clinical research

21 January 2018

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Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials

21 January 2018

1 reference

Genetic associations in large versus small studies: an empirical assessment

21 January 2018

1 reference

Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease

21 January 2018

1 reference

A general framework for multiple testing dependence

21 January 2018

1 reference

Higher criticism thresholding: Optimal feature selection when useful features are rare and weak

21 January 2018

1 reference

Analysis of the metabolic footprint and tissue metabolome of placental villous explants cultured at different oxygen tensions reveals novel redox biomarkers

21 January 2018

1 reference

Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover

21 January 2018

1 reference

Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response

21 January 2018

1 reference

Within-day reproducibility of an HPLC-MS-based method for metabonomic analysis: application to human urine

21 January 2018

1 reference

Application of ultra performance liquid chromatography-mass spectrometry to profiling rat and dog bile

21 January 2018

1 reference

Metabolite profiling of fecal water extracts from human colorectal cancer

21 January 2018

1 reference

Understanding the human salivary metabolome

21 January 2018

1 reference

Metabolomics and its application for non-invasive embryo assessment in IVF.

21 January 2018

1 reference

Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver

21 January 2018

1 reference

Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1H NMR spectroscopy

21 January 2018

1 reference

Detection of metabolic alterations in non-tumor gastrointestinal tissue of the Apc(Min/+) mouse by (1)H MAS NMR spectroscopy.

21 January 2018

1 reference

Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magic-angle-spinning NMR spectroscopy

21 January 2018

1 reference

Multiparametric analysis of amino acids and organic acids in rat brain tissues using GC/MS.

21 January 2018

1 reference

Effective quenching processes for physiologically valid metabolite profiling of suspension cultured Mammalian cells

21 January 2018

1 reference

Effects of mainstream cigarette smoke on the global metabolome of human lung epithelial cells

21 January 2018

1 reference

Cross-platform Q-TOF validation of global exo-metabolomic analysis: application to human glioblastoma cells treated with the standard PI 3-Kinase inhibitor LY294002.

21 January 2018

1 reference

Live single-cell metabolomics of tryptophan and histidine metabolites in a rat basophil leukemia cell

21 January 2018

1 reference

Prospects for clinical cancer metabolomics using stable isotope tracers

21 January 2018

1 reference

Identification of small molecules from human embryonic stem cells using metabolomics

21 January 2018

1 reference

Changes in the metabolic footprint of placental explant-conditioned culture medium identifies metabolic disturbances related to hypoxia and pre-eclampsia.

21 January 2018

1 reference

Analysis of the adult human plasma metabolome

21 January 2018

1 reference

A Functional Analysis of Mouse Models of Cardiac Disease through Metabolic Profiling

21 January 2018

1 reference

Integrative biological analysis of the APOE*3-leiden transgenic mouse

21 January 2018

1 reference

ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit

21 January 2018

1 reference

Proteomic and metabolomic analyses of atherosclerotic vessels from apolipoprotein E-deficient mice reveal alterations in inflammation, oxidative stress, and energy metabolism

21 January 2018

1 reference

Metabolic profiles of dystrophin and utrophin expression in mouse models of Duchenne muscular dystrophy

21 January 2018

1 reference

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models.

21 January 2018

1 reference

Peroxisome proliferator-activated receptor alpha (PPARalpha) influences substrate utilization for hepatic glucose production

21 January 2018

1 reference

A combined 1H-NMR spectroscopy- and mass spectrometry-based metabolomic study of the PPAR-alpha null mutant mouse defines profound systemic changes in metabolism linked to the metabolic syndrome.

21 January 2018

1 reference

PPAR gamma 2 prevents lipotoxicity by controlling adipose tissue expandability and peripheral lipid metabolism

21 January 2018

1 reference

Adaptation and failure of pancreatic beta cells in murine models with different degrees of metabolic syndrome

21 January 2018

1 reference

Adipose tissue inflammation and increased ceramide content characterize subjects with high liver fat content independent of obesity.

21 January 2018

1 reference

Global transcript profiles of fat in monozygotic twins discordant for BMI: pathways behind acquired obesity

21 January 2018

1 reference

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

21 January 2018

1 reference

Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics

21 January 2018

1 reference

Detection and identification of novel metabolomic biomarkers in preeclampsia

21 January 2018

1 reference

Novel biomarkers for pre-eclampsia detected using metabolomics and machine learning

21 January 2018

1 reference

Metabolomic profiling reveals distinct patterns of myocardial substrate use in humans with coronary artery disease or left ventricular dysfunction during surgical ischemia/reperfusion.

21 January 2018

1 reference

Defining a metabolic phenotype in the brain of a transgenic mouse model of spinocerebellar ataxia 3.

21 January 2018

1 reference

Metabolic profiles of cancer cells

21 January 2018

1 reference

Metabolic characterization of distinct neuroanatomical regions in rats by magic angle spinning 1H nuclear magnetic resonance spectroscopy

21 January 2018

1 reference

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

21 January 2018

1 reference

Automated classification of short echo time in in vivo 1H brain tumor spectra: a multicenter study.

21 January 2018

1 reference

Metabolic profiling of genetic disorders: a multitissue (1)H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue

21 January 2018

1 reference

Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection

21 January 2018

1 reference

Metabolomic analysis and signatures in motor neuron disease

21 January 2018

1 reference

Metabolic characterization of the R6/2 transgenic mouse model of Huntington's disease by high-resolution MAS 1H NMR spectroscopy

21 January 2018

1 reference

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

21 January 2018

1 reference

Proton MR CSF analysis and a new software as predictors for the differentiation of meningitis in children.

21 January 2018

1 reference

Metabolic profiling of patients with schizophrenia

21 January 2018

1 reference

Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress

21 January 2018

1 reference

Characteristic metabolic profiles revealed by 1H NMR spectroscopy for three types of human brain and nervous system tumours.

21 January 2018

1 reference

Metabolic profiles of human brain tumors using quantitative in vivo 1H magnetic resonance spectroscopy

21 January 2018

1 reference

Mass spectrometry-based metabolic profiling reveals different metabolite patterns in invasive ovarian carcinomas and ovarian borderline tumors.

21 January 2018

1 reference

Non-destructive quantitation of spermine in human prostate tissue samples using HRMAS 1H NMR spectroscopy at 9.4 T.

21 January 2018

1 reference

Metabonomics in toxicology: a review

21 January 2018

1 reference

Metabonomic modeling of drug toxicity

21 January 2018

1 reference

NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology

21 January 2018

1 reference

NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition

21 January 2018

1 reference

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project.

21 January 2018

1 reference

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

21 January 2018

1 reference

Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach

21 January 2018

1 reference

Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns

21 January 2018

1 reference

Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation.

21 January 2018

1 reference

Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography

21 January 2018

1 reference

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria

21 January 2018

1 reference

Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity.

21 January 2018

1 reference

Analytical strategies in lipidomics and applications in disease biomarker discovery

21 January 2018

1 reference

Biomarker discovery using high-dimensional lipid analysis

21 January 2018

1 reference

Membrane lipids as signaling molecules

21 January 2018

1 reference

A matter of fat: an introduction to lipidomic profiling methods

21 January 2018

1 reference

The emerging field of lipidomics

21 January 2018

1 reference

Identification of double bond position in lipids: from GC to OzID.

21 January 2018

1 reference

Bioinformatics and computational approaches applicable to lipidomics

21 January 2018

1 reference

Accumulation of long-chain acylcarnitine and 3-hydroxy acylcarnitine molecular species in diabetic myocardium: identification of alterations in mitochondrial fatty acid processing in diabetic myocardium by shotgun lipidomics

21 January 2018

1 reference

New insights into cardiovascular and lipid metabolomics

21 January 2018

1 reference

Enhanced modification of cardiolipin during ischemia in the aged heart

21 January 2018

1 reference

Cardiolipin, the heart of mitochondrial metabolism.

21 January 2018

1 reference

Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making

21 January 2018

1 reference

Role of Lipids in Brain Injury and Diseases

21 January 2018

1 reference

Lipid mediators regulating pain sensitivity

21 January 2018

1 reference

Membrane lipids and cell death: an overview.

21 January 2018

1 reference

Biomarkers of dietary energy restriction in women at increased risk of breast cancer.

21 January 2018

1 reference

Measurement of dietary exposure: a challenging problem which may be overcome thanks to metabolomics?

21 January 2018

1 reference

Biomarkers in nutritional epidemiology: applications, needs and new horizons

21 January 2018

1 reference

(13)C-based metabolic flux analysis.

21 January 2018

1 reference

Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM)

21 January 2018

1 reference

Novel biological insights through metabolomics and 13C-flux analysis.

21 January 2018

1 reference

Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments.

21 January 2018

1 reference

Measurement of gluconeogenesis and pyruvate recycling in the rat liver: a simple analysis of glucose and glutamate isotopomers during metabolism of [1,2,3-(13)C3]propionate.

21 January 2018

1 reference

Reflections on the application of 13C-MRS to research on brain metabolism

21 January 2018

1 reference

In vivo 13C NMR measurements of cerebral glutamine synthesis as evidence for glutamate-glutamine cycling

21 January 2018

1 reference

Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy

21 January 2018

1 reference

Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics

21 January 2018

1 reference

Cellular imaging with secondary ion mass spectrometry

21 January 2018

1 reference

Cluster TOF-SIMS imaging: a new light for in situ metabolomics?

21 January 2018

1 reference

Mass spectrometry sampling under ambient conditions with desorption electrospray ionization

21 January 2018

1 reference

Clathrate nanostructures for mass spectrometry

21 January 2018

1 reference

Responsive MRI agents for sensing metabolism in vivo

21 January 2018

1 reference

Functional genomics and NMR spectroscopy

21 January 2018

1 reference

Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum

21 January 2018

1 reference

Predicting metabolic biomarkers of human inborn errors of metabolism

21 January 2018

1 reference

BioMagResBank (BMRB) as a partner in the Worldwide Protein Data Bank (wwPDB): new policies affecting biomolecular NMR depositions

21 January 2018

1 reference

Self-consistent metabolic mixture analysis by heteronuclear NMR. Application to a human cancer cell line

21 January 2018

1 reference

Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry

21 January 2018

1 reference

MetaFIND: a feature analysis tool for metabolomics data.

21 January 2018

1 reference

MetaboMiner--semi-automated identification of metabolites from 2D NMR spectra of complex biofluids

21 January 2018

1 reference

Towards de novo identification of metabolites by analyzing tandem mass spectra

21 January 2018

1 reference

Explanatory signal interpretation and metabolite identification strategies for nominal mass FIE-MS metabolite fingerprints

21 January 2018

1 reference

Probabilistic assignment of formulas to mass peaks in metabolomics experiments

21 January 2018

1 reference

Seven Golden Rules for heuristic filtering of molecular formulas obtained by accurate mass spectrometry

21 January 2018

1 reference

Proposed minimum reporting standards for chemical analysis

21 January 2018

1 reference

Natural product analysis over the last decades

21 January 2018

1 reference

GMD@CSB.DB: the Golm Metabolome Database

21 January 2018

1 reference

GC-MS libraries for the rapid identification of metabolites in complex biological samples

21 January 2018

1 reference

FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry

21 January 2018

1 reference

Evaluation of protocols for reproducible electrospray in-source collisionally induced dissociation on various liquid chromatography/mass spectrometry instruments and the development of spectral libraries

21 January 2018

1 reference

Reproducible product-ion tandem mass spectra on various liquid chromatography/mass spectrometry instruments for the development of spectral libraries

21 January 2018

1 reference

A proposed framework for the description of plant metabolomics experiments and their results

21 January 2018

1 reference

Standard reporting requirements for biological samples in metabolomics experiments: microbial and in vitro biology experiments.

21 January 2018

1 reference

Standard reporting requirements for biological samples in metabolomics experiments: environmental context

21 January 2018

1 reference

Proposed minimum reporting standards for data analysis in metabolomics

21 January 2018

1 reference

MeMo: a hybrid SQL/XML approach to metabolomic data management for functional genomics

21 January 2018

1 reference

Parallel analysis of transcript and metabolic profiles: a new approach in systems biology

21 January 2018

1 reference

Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae

21 January 2018

1 reference

Metabolomics: Current analytical platforms and methodologies

21 January 2018

1 reference

Metabolic Profile Biomarkers of Metal Contamination in a Sentinel Terrestrial Species Are Applicable Across Multiple Sites

21 January 2018

1 reference

Evaluation of automated electrospray-TOF mass spectrometryfor metabolic fingerprinting of the plant metabolome

21 January 2018

1 reference

Data Mining and Knowledge Discovery with Evolutionary Algorithms

21 January 2018

1 reference

Minimum reporting standards for plant biology context information in metabolomic studies

21 January 2018

1 reference

Proposed reporting requirements for the description of NMR-based metabolomics experiments

21 January 2018

1 reference

Metabolomics standards initiative: ontology working group work in progress

21 January 2018

1 reference

Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

21 January 2018

1 reference

Statistical Correlation and Projection Methods for Improved Information Recovery from Diffusion-Edited NMR Spectra of Biological Samples

21 January 2018

1 reference

Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

21 January 2018

1 reference

Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe

21 January 2018

1 reference

Comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry (GC × GC-TOF) for high resolution metabolomics: biomarker discovery on spleen tissue extracts of obese NZO compared to lean C57BL/6 mice

21 January 2018

1 reference

Metabolite identification via the Madison Metabolomics Consortium Database

21 January 2018

1 reference

Metabonomics, dietary influences and cultural differences: a 1H NMR-based study of urine samples obtained from healthy British and Swedish subjects

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1039/B906712B

1 reference

23 August 2017

1 reference

PubMed ID

20717559